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Results for “Advanced Unresectable Melanoma”

189 trials

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Showing 20 of 189 results

Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Early research (Phase 1)Study completedNCT02020707
What this trial is testing

Nab-Paclitaxel and Bevacizumab in Treating Patients With Unresectable Stage IV Melanoma or Gynecological Cancers

Who this might be right for
Cervical AdenocarcinomaCervical AdenosarcomaCervical Adenosquamous Carcinoma+45 more
Mayo Clinic 43
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Testing effectiveness (Phase 2)Looking for participantsNCT07237100
What this trial is testing

Mirdametinib in Patients With Advanced NF1-mutant Melanoma

Who this might be right for
Advanced Unresectable MelanomaMetastatic Melanoma
Kevin Kim, MD 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT04639219
What this trial is testing

T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations

Who this might be right for
Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast
AstraZeneca 102
Large-scale testing (Phase 3)Looking for participantsNCT05727904
What this trial is testing

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

Who this might be right for
Metastatic MelanomaUnresectable MelanomaMelanoma
Iovance Biotherapeutics, Inc. 670
Testing effectiveness (Phase 2)Study completedNCT00003989
What this trial is testing

ISIS 3521 in Treating Patients With Advanced, Unresectable, or Metastatic Non-small Cell Lung Cancer or Unresectable or Metastatic Melanoma

Who this might be right for
Lung CancerMelanoma (Skin)
European Organisation for Research and Treatment of Cancer - EORTC 50
Early research (Phase 1)Ended earlyNCT02419495
What this trial is testing

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Who this might be right for
Advanced Malignant Solid NeoplasmClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+26 more
M.D. Anderson Cancer Center 221
Early research (Phase 1)Active Not RecruitingNCT04572451
What this trial is testing

Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanoma

Who this might be right for
MelanomaUnresectable Solid TumorsNeoplasms+7 more
Yana Najjar 50
Testing effectiveness (Phase 2)Looking for participantsNCT05267626
What this trial is testing

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Who this might be right for
Advanced Solid TumorMetastatic CancerCutaneous Melanoma+1 more
Aulos Bioscience, Inc. 159
Large-scale testing (Phase 3)Study completedNCT01689519
What this trial is testing

A Study Comparing Vemurafenib Versus Vemurafenib Plus Cobimetinib in Participants With Metastatic Melanoma

Who this might be right for
Malignant Melanoma
Hoffmann-La Roche 495
Testing effectiveness (Phase 2)Active Not RecruitingNCT05061134
What this trial is testing

Ceralasertib Monotherapy and Ceralasertib Plus Durvalumab in Patients With Melanoma and Resistance to PD-(L)1 Inhibition

Who this might be right for
Melanoma
AstraZeneca 194
Testing effectiveness (Phase 2)Study completedNCT02645149
What this trial is testing

Molecular Profiling and Matched Targeted Therapy for Patients With Unresectable Advanced or Metastatic Melanoma

Who this might be right for
Melanoma
Melanoma Institute Australia 216
Testing effectiveness (Phase 2)Looking for participantsNCT06594991
What this trial is testing

Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma

Who this might be right for
Advanced Melanoma
Memorial Sloan Kettering Cancer Center 88
Testing effectiveness (Phase 2)WithdrawnNCT05561491
What this trial is testing

ONCOS-102 in Combination With Other Novel Immune-therapies in Advanced Treatment-resistant Melanoma Patients

Who this might be right for
Melanoma
Targovax Oy
Testing effectiveness (Phase 2)Study completedNCT00096083
What this trial is testing

Hepatic Arterial Infusion of Melphalan With Hepatic Perfusion in Treating Patients With Unresectable Liver Cancer

Who this might be right for
Cancer
Delcath Systems Inc. 56
Testing effectiveness (Phase 2)Ended earlyNCT02410863
What this trial is testing

Biopsy- and Biology-driven Optimization of Targeted Therapy in Subjects With Advanced Melanoma

Who this might be right for
Malignant Melanoma
Prof. Dr. med. Dirk Schadendorf 10
Testing effectiveness (Phase 2)Ended earlyNCT04387071
What this trial is testing

CMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma

Who this might be right for
Locally Advanced Malignant Solid NeoplasmMetastatic Pancreatic AdenocarcinomaStage IV Pancreatic Cancer AJCC v8+1 more
University of Southern California 2
Early research (Phase 1)Ended earlyNCT03978611
What this trial is testing

Assess Safety of Relatlimab With Ipilimumab in Participants With Advanced Melanoma Who Progressed on Anti-Programmed Cell Death Protein 1 (Anti-PD-1) Treatment

Who this might be right for
Melanoma
Bristol-Myers Squibb 11
Testing effectiveness (Phase 2)Study completedNCT01990859
What this trial is testing

Phase 2 Study of Ipilimumab in Japanese Advanced Melanoma Patients

Who this might be right for
Melanoma
Bristol-Myers Squibb 20
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