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Results for “Advanced Unresectable Melanoma”

186 trials

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Showing 20 of 186 results

Early research (Phase 1)Study completedNCT03864042
What this trial is testing

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsMetastatic Melanoma
Pfizer 56
Testing effectiveness (Phase 2)Looking for participantsNCT05136196
What this trial is testing

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+22 more
National Cancer Institute (NCI)
Early research (Phase 1)Active Not RecruitingNCT05907304
What this trial is testing

Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations

Who this might be right for
Advanced or Metastatic Solid Tumors
Erasca, Inc. 86
Testing effectiveness (Phase 2)Active Not RecruitingNCT04462406
What this trial is testing

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

Who this might be right for
Advanced MelanomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+8 more
ECOG-ACRIN Cancer Research Group 150
Testing effectiveness (Phase 2)Looking for participantsNCT07237100
What this trial is testing

Mirdametinib in Patients With Advanced NF1-mutant Melanoma

Who this might be right for
Advanced Unresectable MelanomaMetastatic Melanoma
Kevin Kim, MD 10
Testing effectiveness (Phase 2)Study completedNCT04493203
What this trial is testing

Nivolumab Plus Axitinib in Patients With Anti-PD1 Refractory Advanced Melanoma

Who this might be right for
Advanced MelanomaUnresectable Melanoma
Yana Najjar 31
Testing effectiveness (Phase 2)Study completedNCT03484923
What this trial is testing

Study of Efficacy and Safety of Novel Spartalizumab Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma

Who this might be right for
Melanoma
Novartis Pharmaceuticals 196
Testing effectiveness (Phase 2)Study completedNCT04091217
What this trial is testing

Atezolizumab in Combination With Bevacizumab in Patients With Unresectable Locally Advanced or Metastatic Mucosal Melanoma

Who this might be right for
Melanoma
Hoffmann-La Roche 43
Testing effectiveness (Phase 2)Study completedNCT00602576
What this trial is testing

Temozolomide and Sorafenib in Treating Patients With Metastatic or Unresectable Melanoma

Who this might be right for
Melanoma (Skin)
Abramson Cancer Center at Penn Medicine 169
Testing effectiveness (Phase 2)Study completedNCT03033576
What this trial is testing

Testing Treatment With Ipilimumab and Nivolumab Compared to Treatment With Ipilimumab Alone in Advanced Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Melanoma of Unknown Primary+3 more
National Cancer Institute (NCI) 94
Testing effectiveness (Phase 2)Study completedNCT00700882
What this trial is testing

Dasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By Surgery

Who this might be right for
Melanoma (Skin)
Eastern Cooperative Oncology Group 81
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Testing effectiveness (Phase 2)Study completedNCT03679767
What this trial is testing

INCMGA00012 in Participants With Selected Solid Tumors (POD1UM-203)

Who this might be right for
Metastatic Non-small Cell Lung CancerLocally Advanced Urothelial CancerMetastatic Urothelial Cancer+4 more
Incyte Corporation 121
Early research (Phase 1)Ended earlyNCT00791271
What this trial is testing

Parallel Phase I/II Trial of Decitabine and Peg-Interferon in Melanoma: Phase I Portion

Who this might be right for
Melanoma
M.D. Anderson Cancer Center 17
Very early researchEnded earlyNCT00499733
What this trial is testing

Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer

Who this might be right for
Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 19
Early research (Phase 1)Active Not RecruitingNCT05867303
What this trial is testing

A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
MelanomaUrothelial CarcinomaRenal Cell Carcinoma+3 more
RemeGen Co., Ltd. 48
Early research (Phase 1)Study completedNCT01673737
What this trial is testing

A Phase I/Ib Trial for the Evaluation of SAR260301 in Monotherapy or in Combination With Vemurafenib in Patients With Various Advanced Cancer

Who this might be right for
Neoplasm Malignant
Sanofi 75
Testing effectiveness (Phase 2)Looking for participantsNCT04598009
What this trial is testing

Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma

Who this might be right for
Melanoma Stage IIIMelanoma Stage IV
University of California, San Francisco 25
Testing effectiveness (Phase 2)Looking for participantsNCT07627698
What this trial is testing

Dual-Target CSPG4/GD2 CAR-NK Cells for Advanced Melanoma

Who this might be right for
Unresectable MelanomaMetastatic Cutaneous MelanomaMetastatic Uveal Melanoma
Beijing Biotech 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05539118
What this trial is testing

Interferon-α1b Combined With Toripalimab and Anlotinib Hydrochloride in Advanced Unresectable Melanoma

Who this might be right for
Melanoma
Xijing Hospital 48
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