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Results for “Advanced Urothelial Carcinoma”

488 trials

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Showing 20 of 488 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03854474
What this trial is testing

Testing the Addition of Tazemetostat to the Immunotherapy Drug, Pembrolizumab (MK-3475), in Advanced Urothelial Carcinoma

Who this might be right for
Locally Advanced Urothelial CarcinomaMetastatic Urothelial CarcinomaStage III Bladder Cancer AJCC v8+1 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)WithdrawnNCT05234606
What this trial is testing

A Safety and Preliminary Efficacy Study of SBT6290 Alone and in Combination With PD-(L)1 Inhibitors in Select Advanced Solid Tumors

Who this might be right for
Urothelial CarcinomaTriple Negative Breast CancerNon-small Cell Lung Cancer+2 more
Silverback Therapeutics
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07185945
What this trial is testing

Zanzalintinib for Advanced Urothelial Carcinoma Progressing After Prior Therapy

Who this might be right for
Advanced Urothelial Carcinoma
Guru Sonpavde 44
Testing effectiveness (Phase 2)Ended earlyNCT06171789
What this trial is testing

PRO1107 in Patients With Advanced Solid Tumors

Who this might be right for
Endometrial CancerOvarian CancerTriple Negative Breast Cancer+3 more
Genmab 33
Testing effectiveness (Phase 2)Study completedNCT03421652
What this trial is testing

Nivolumab and RT in Treating Patients With Localized/Locally Advanced Urothelial Bladder Cancer Ineligible for Chemo

Who this might be right for
Stage II Bladder Urothelial Carcinoma AJCC v6 and v7Stage III Bladder Urothelial Carcinoma AJCC v6 and v7Stage IV Bladder Urothelial Carcinoma AJCC v7
Barbara Ann Karmanos Cancer Institute 20
Large-scale testing (Phase 3)Looking for participantsNCT06738251
What this trial is testing

A Phase III Study of SHR-A2102 Versus Investigator-selected Therapy in Advanced Urothelial Carcinoma

Who this might be right for
Advanced Urothelial Carcinoma
Shanghai Hengrui Pharmaceutical Co., Ltd. 402
Not applicableNot Yet RecruitingNCT06798246
What this trial is testing

HEFTME System for Adjuvant Therapeutic Selection of Locally Advanced UTUC Postoperatively:A Perspective Cohort Study

Who this might be right for
Upper Tract Urothelial Carcinoma
Peking University First Hospital 200
Testing effectiveness (Phase 2)Study completedNCT01090466
What this trial is testing

Gemcitabine Hydrochloride, Cisplatin, and Temsirolimus as First-Line Therapy in Treating Patients With Locally Advanced and/or Metastatic Transitional Cell Cancer of the Urothelium

Who this might be right for
Bladder CancerTransitional Cell Cancer of the Renal Pelvis and UreterUrethral Cancer
Cardiff University 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT04152499
What this trial is testing

Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)

Who this might be right for
Epithelial Ovarian CancerGastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma+7 more
Klus Pharma Inc. 1,410
Testing effectiveness (Phase 2)Active Not RecruitingNCT05845814
What this trial is testing

Efficacy and Safety of Pembrolizumab Plus Enfortumab Vedotin (EV) +/- Investigational Agents in First-Line Metastatic Urothelial Carcinoma (mUC) (MK-3475-04B/KEYMAKER-U04)

Who this might be right for
Metastatic Urothelial CarcinomaUrothelial Neoplasms
Merck Sharp & Dohme LLC 390
Testing effectiveness (Phase 2)Study completedNCT00151034
What this trial is testing

Trastuzumab (Herceptin), Paclitaxel, Carboplatin and Gemcitabine in Advanced Urothelial Cancer

Who this might be right for
Urologic Neoplasms
University of Michigan Rogel Cancer Center 33
Testing effectiveness (Phase 2)Looking for participantsNCT04895709
What this trial is testing

BMS-986340 as Monotherapy and in Combination With Nivolumab or Docetaxel in Participants With Advanced Solid Tumors

Who this might be right for
Cervical CancerGastric/Gastroesophageal Junction AdenocarcinomaMicrosatellite Stable Colorectal Cancer+8 more
Bristol-Myers Squibb 949
Early research (Phase 1)Looking for participantsNCT06293898
What this trial is testing

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

Who this might be right for
Endometrial CancerCervical CancerOvarian Cancer+7 more
SystImmune Inc. 280
Testing effectiveness (Phase 2)Study completedNCT00002914
What this trial is testing

Piritrexim in Treating Patients With Advanced Cancer of the Urinary Tract

Who this might be right for
Bladder CancerTransitional Cell Cancer of the Renal Pelvis and UreterUrethral Cancer
Eastern Cooperative Oncology Group 40
Testing effectiveness (Phase 2)Looking for participantsNCT07043972
What this trial is testing

Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
Fox Chase Cancer Center 55
Testing effectiveness (Phase 2)Looking for participantsNCT05335941
What this trial is testing

Evaluate the Triplet Combination of Pemetrexed Plus AB928 (Etrumadenant) + AB122 (Zimberelimab) in Patients With Previously Treated Advanced or Metastatic MTAP Deficient Urothelial Carcinoma

Who this might be right for
Urothelial CarcinomaMetastatic Cancer
M.D. Anderson Cancer Center 20
Early research (Phase 1)Ended earlyNCT03915405
What this trial is testing

KHK2455 (IDO Inhibitor) Plus Avelumab in Adult Subjects With Advanced Bladder Cancer

Who this might be right for
Urothelial Carcinoma
Kyowa Kirin, Inc. 16
Testing effectiveness (Phase 2)Active Not RecruitingNCT04140526
What this trial is testing

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC

Who this might be right for
Non Small Cell Lung CancerAdvanced Solid TumorMetastatic Melanoma+16 more
OncoC4, Inc. 733
Early research (Phase 1)Ended earlyNCT05121948
What this trial is testing

HC-7366 to Establish the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D)

Who this might be right for
Squamous Cell Carcinoma of Head and NeckColo-rectal CancerNon Small Cell Lung Cancer+3 more
HiberCell, Inc. 35
Not applicableActive Not RecruitingNCT07063758
What this trial is testing

A Biomarker Study to Predict Treatment Outcomes of Enfortumab Vedotin in Advanced Urothelial Carcinoma

Who this might be right for
Advanced Urothelial Carcinoma
National Taiwan University Clinical Trial Center 200
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