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Results for “Advanced Urothelial Carcinoma”

505 trials

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Showing 20 of 505 results

Early research (Phase 1)Looking for participantsNCT05176483
What this trial is testing

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

Who this might be right for
Renal Cell Carcinoma (RCC)Metastatic Castration-Resistant Prostate Cancer (mCRPC)Urothelial Carcinoma (UC)+7 more
Exelixis 1,314
Testing effectiveness (Phase 2)Study completedNCT03665285
What this trial is testing

A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsLung CancerBreast Cancer+6 more
NextCure, Inc. 109
Early research (Phase 1)WithdrawnNCT07217496
What this trial is testing

N-803 in Combination With Pembrolizumab and Enfortumab Vedotin for Treatment of Urothelial Cancer

Who this might be right for
Metastatic Urothelial CarcinomaUrothelial CarcinomaLocally Advanced Urothelial Carcinoma+1 more
Vadim S Koshkin
Testing effectiveness (Phase 2)Active Not RecruitingNCT05923190
What this trial is testing

Enfortumab Vedotin Schedule De-escalation in Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial CarcinomaMetastatic Urothelial CarcinomaLocally Advanced Urothelial Carcinoma
Fox Chase Cancer Center 60
Testing effectiveness (Phase 2)Looking for participantsNCT06923761
What this trial is testing

EMITT-1 (ERAP Mediated Immunopeptidome Targeting Trial - 1)

Who this might be right for
Advanced Solid Malignancy
Grey Wolf Therapeutics 300
Early research (Phase 1)Study completedNCT03739931
What this trial is testing

Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies

Who this might be right for
Dose Escalation: Relapsed/Refractory Solid Tumor Malignancies or LymphomaDose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC Lymphoma
ModernaTX, Inc. 134
Early research (Phase 1)Study completedNCT04242199
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMSI-H/dMMR TumorsCutaneous Squamous Cell Carcinoma+9 more
Incyte Corporation 182
Early research (Phase 1)Active Not RecruitingNCT04432857
What this trial is testing

AN0025 and Pembrolizumab Combination in Advanced Solid Tumors

Who this might be right for
Triple-negative Breast CancerNSCLC, Squamous or Non-SquamousUrothelial Carcinoma of the Bladder+2 more
Adlai Nortye Biopharma Co., Ltd. 63
Testing effectiveness (Phase 2)Active Not RecruitingNCT04953104
What this trial is testing

ARID1A and/or KDM6A Mutation and CXCL13 Expression

Who this might be right for
Locally Advanced Bladder Urothelial CarcinomaLocally Advanced Renal Pelvis Urothelial CarcinomaLocally Advanced Ureter Urothelial Carcinoma+29 more
M.D. Anderson Cancer Center 6
Early research (Phase 1)Looking for participantsNCT05614739
What this trial is testing

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

Who this might be right for
Urinary Bladder NeoplasmsNeoplasm MetastasisUreteral Neoplasms
Eli Lilly and Company 535
Early research (Phase 1)Ended earlyNCT05233436
What this trial is testing

PF-07265028 As Single Agent And In Combination With Sasanlimab in Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorsGastric CancerGastroesophageal Junction Cancer+3 more
Pfizer 21
Not applicableStudy completedNCT05366725
What this trial is testing

Learn About the Study Medicine (Called Avelumab) in People With Advanced Urothelial Cancer After Chemotherapy

Who this might be right for
Urothelial Cancer
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 106
Early research (Phase 1)Active Not RecruitingNCT03252938
What this trial is testing

Feasibility and Safety of IMP321 (Eftilagimod Alpha) for Advanced Stage Solid Tumors

Who this might be right for
Solid TumorsPeritoneal CarcinomatosisNSCLC Adenocarcinoma+1 more
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 83
Testing effectiveness (Phase 2)Study completedNCT01828736
What this trial is testing

Efficacy of Combination of Trastuzumab to Gemcitabine - Platinum Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Recurrent Bladder CancerStage IV Bladder CancerTransitional Cell Carcinoma of the Bladder
Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie 61
Large-scale testing (Phase 3)Not Yet RecruitingNCT07526792
What this trial is testing

SYS6002 vs Chemotherapy in Patients With Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
CSPC Megalith Biopharmaceutical Co.,Ltd. 406
Testing effectiveness (Phase 2)Looking for participantsNCT04895709
What this trial is testing

BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

Who this might be right for
Cervical CancerGastric/Gastroesophageal Junction AdenocarcinomaMicrosatellite Stable Colorectal Cancer+8 more
Bristol-Myers Squibb 1,109
Large-scale testing (Phase 3)Active Not RecruitingNCT03967977
What this trial is testing

Study of Tislelizumab in Combination With Chemotherapy Compared to Chemotherapy Alone for Participants With Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
BeiGene 420
Testing effectiveness (Phase 2)Looking for participantsNCT07287995
What this trial is testing

ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Malignant Solid Tumors
Astellas Pharma Global Development, Inc. 428
Early research (Phase 1)Ended earlyNCT04628780
What this trial is testing

Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid Tumors

Who this might be right for
Non-small-cell Lung CancerSquamous Cell Carcinoma of the Head and NeckRenal Cell Carcinoma+3 more
Pfizer 37
Testing effectiveness (Phase 2)WithdrawnNCT05687721
What this trial is testing

Copanlisib and Avelumab as a Maintenance Therapy for Advanced Bladder Cancer

Who this might be right for
Advanced Urothelial Carcinoma
VA Office of Research and Development
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