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Results for “Advanced or Metastatic Esophageal Squamous Cell Carcinoma”

118 trials

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Showing 20 of 118 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07128693
What this trial is testing

A Single-center, Multicohort, Phase II Clinical Study Evaluating the Combination Therapy of Sacituzumab Tirumotecan in Patients With Unresectable, Locally Advanced, Recurrent, or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University 60
Large-scale testing (Phase 3)Study completedNCT03829969
What this trial is testing

Toripalimab or Placebo With Paclitaxel and Cisplatin in Esophageal Squamous Cell Carcinoma

Who this might be right for
Advanced or Metastatic Esophageal Squamous Cell Cancer Without Previous Systemic Chemotherapy
Shanghai Junshi Bioscience Co., Ltd. 514
Testing effectiveness (Phase 2)UnknownNCT03603756
What this trial is testing

SHR-1210 in Combination With Apatinib and Chemotherapy in Patients With Advanced Esophageal Squamous Cell Cancer

Who this might be right for
Esophageal Squamous Cell Carcinoma
Chinese Academy of Medical Sciences 45
Large-scale testing (Phase 3)Study completedNCT03783442
What this trial is testing

Tislelizumab (BGB-A317) in Combination With Chemotherapy as First Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
BeiGene 649
Large-scale testing (Phase 3)Study completedNCT03143153
What this trial is testing

Evaluate Efficacy in Subjects With Esophageal Cancer Treated With Nivolumab and Ipilimumab or Nivolumab Combined With Fluorouracil Plus Cisplatin Versus Fluorouracil Plus Cisplatin

Who this might be right for
Various Advanced Cancer
Bristol-Myers Squibb 970
Testing effectiveness (Phase 2)UnknownNCT05990231
What this trial is testing

Cadonilimab/Anlotinib in Locally Advanced or Relapsed/Metastatic ESCC Patients After Failure of PD-1 Combined With Platinum-containing Chemotherapy

Who this might be right for
Esophageal Squamous Cell Carcinoma
Second Affiliated Hospital, School of Medicine, Zhejiang University 35
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Testing effectiveness (Phase 2)UnknownNCT06055153
What this trial is testing

DV Combined With PD-1 and Platinum-based First-line Treatment in Patients With HER2 IHC2+/3+ ESCC

Who this might be right for
Esophageal Squamous CarcinomaHER-2 Protein Overexpression
Changhai Hospital 20
Testing effectiveness (Phase 2)Study completedNCT04785820
What this trial is testing

Lomvastomig (RO7121661) and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus

Who this might be right for
Advanced or Metastatic Esophageal Squamous Cell Carcinoma
Hoffmann-La Roche 206
Testing effectiveness (Phase 2)Looking for participantsNCT05910827
What this trial is testing

Study of an Anti-HER3 Antibody, HMBD-001, With Docetaxel +/- Cetuximab in Advanced Squamous Non-small Cell Lung Cancers, and HMBD-001 + Cetuximab in Advanced Squamous Cell Cancers

Who this might be right for
Advanced or Metastatic Squamous Non-Small Cell Lung CancerAdvanced Head and Neck Squamous Cell CarcinomaAdvanced Esophageal Squamous Cell Carcinoma+2 more
Hummingbird Bioscience
Testing effectiveness (Phase 2)Looking for participantsNCT06780111
What this trial is testing

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

Who this might be right for
Esophageal Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 298
Early research (Phase 1)Study completedNCT03708328
What this trial is testing

A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid Tumors

Who this might be right for
Solid TumorsMetastatic MelanomaNon-small Cell Lung Cancer (NSCLC)+2 more
Hoffmann-La Roche 134
Not applicableUnknownNCT04654403
What this trial is testing

Study of First-line Camrelizumab With or Without Chemotherapy for Advanced Esophageal Squamous Cell Cancer

Who this might be right for
Esophageal Cancer
The First Affiliated Hospital of Zhengzhou University 337
Testing effectiveness (Phase 2)Study completedNCT04732494
What this trial is testing

Anti-PD-1 Monoclonal Antibody Tislelizumab (BGB-A317) Combined With or Without Anti-TIGIT Monoclonal Antibody Ociperlimab (BGB-A1217) in Participants With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
BeiGene 125
Large-scale testing (Phase 3)Study completedNCT03748134
What this trial is testing

Sintilimab or Placebo With Chemotherapy in Esophageal Squamous Cell Carcinoma ( ORIENT-15 )

Who this might be right for
Esophageal Squamous Cell Carcinoma
Innovent Biologics (Suzhou) Co. Ltd. 746
Large-scale testing (Phase 3)Study completedNCT04187352
What this trial is testing

CS1001 in Subjects With Esophageal Squamous Cell Carcinoma

Who this might be right for
Unresectable Locally Advanced, Recurrent or Metastatic Esophageal Squamous Cell Carcinoma
CStone Pharmaceuticals 540
Early research (Phase 1)Active Not RecruitingNCT05311618
What this trial is testing

Study of NGM438 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors

Who this might be right for
Pancreatic CancerBreast CancerGastric Cancer+13 more
NGM Biopharmaceuticals, Inc 71
Testing effectiveness (Phase 2)Study completedNCT03126110
What this trial is testing

Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic Malignancies

Who this might be right for
Advanced MalignanciesMetastatic Cancer
Incyte Biosciences International Sàrl 145
Early research (Phase 1)Study completedNCT00019110
What this trial is testing

Vaccine Therapy in Treating Patients With Advanced or Recurrent Cancer

Who this might be right for
Anal CancerCervical CancerEsophageal Cancer+3 more
National Cancer Institute (NCI)
Early research (Phase 1)Looking for participantsNCT06238479
What this trial is testing

LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors

Who this might be right for
Metastatic Solid TumorRecurrent Solid TumorAdvanced Solid Tumor+11 more
Eli Lilly and Company 490
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