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Results for “Advanced or Metastatic Gastric or Gastroesophageal Cancer”

179 trials

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Showing 20 of 179 results

Testing effectiveness (Phase 2)UnknownNCT05019794
What this trial is testing

Infigratinib in Subjects With GC or GEJ With FGFR2 Amplification or Other Solid Tumors With Other FGFR Alterations

Who this might be right for
Gastric CancerGastroesophageal Junction AdenocarcinomaSolid Tumor
LianBio LLC 80
Testing effectiveness (Phase 2)Study completedNCT01443065
What this trial is testing

MEGA (Met or EGFR Inhibition in Gastroesophageal Adenocarcinoma): FOLFOX Alone or in Combination With AMG 102 or Panitumumab as First-line Treatment in Patients With Advanced Gastroesophageal Adenocarcinoma

Who this might be right for
Malignant Neoplasm of EsophagusMalignant Neoplasm of Stomach
UNICANCER 162
Large-scale testing (Phase 3)Study completedNCT00020787
What this trial is testing

Vaccine Therapy Plus Chemotherapy in Treating Patients With Metastatic or Locally Recurrent Stomach Cancer or Esophageal Cancer

Who this might be right for
Esophageal CancerGastric Cancer
Jonsson Comprehensive Cancer Center 8
Testing effectiveness (Phase 2)Looking for participantsNCT06650332
What this trial is testing

Cadonilimab Combination Regimen as First-line Treatment for HER2-expressing GC/GEJ Patients

Who this might be right for
Metastatic HER2 Positive Gastroesophageal Junction Cancer
Zhejiang Cancer Hospital 90
Testing effectiveness (Phase 2)Looking for participantsNCT06776770
What this trial is testing

A Phase Ib/II Study of Adebrelimab in Combination with Capecitabine and Oxaliplatin in Cancer

Who this might be right for
Gastric Cancer
Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center 52
Early research (Phase 1)Ended earlyNCT05233436
What this trial is testing

PF-07265028 As Single Agent And In Combination With Sasanlimab in Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorsGastric CancerGastroesophageal Junction Cancer+3 more
Pfizer 21
Testing effectiveness (Phase 2)Looking for participantsNCT06415669
What this trial is testing

Paclitaxel Combined With Apatinib and Adebrelimab in Gastric/Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric/Gastroesophageal Junction Adenocarcinoma
The First Affiliated Hospital of Xiamen University 30
Large-scale testing (Phase 3)Looking for participantsNCT05427383
What this trial is testing

KN026 in Combination With Chemotherapy in HER2 Positive Gastric Cancer Subjects Who Have Failed First-line Therapy

Who this might be right for
Stomach Cancer
Shanghai JMT-Bio Inc. 286
Testing effectiveness (Phase 2)Active Not RecruitingNCT04225117
What this trial is testing

Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)

Who this might be right for
Locally Advanced or Metastatic Malignant Solid Tumors
Astellas Pharma Global Development, Inc. 329
Large-scale testing (Phase 3)Active Not RecruitingNCT05568095
What this trial is testing

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Who this might be right for
Advanced Upper Gastrointestinal Tract Adenocarcinoma
Arcus Biosciences, Inc. 1,040
Large-scale testing (Phase 3)Ended earlyNCT01641939
What this trial is testing

Trastuzumab Emtansine Versus Taxane in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Gastric Cancer

Who this might be right for
Gastric Cancer
Hoffmann-La Roche 415
Testing effectiveness (Phase 2)Study completedNCT02689284
What this trial is testing

Combination Margetuximab and Pembrolizumab for Advanced, Metastatic HER2(+) Gastric or Gastroesophageal Junction Cancer

Who this might be right for
Gastric CancerStomach CancerEsophageal Cancer
MacroGenics 95
Early research (Phase 1)Enrolling By InvitationNCT07218003
What this trial is testing

A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4

Who this might be right for
Non Small Cell Lung CancerCervical CancerHead and Neck Squamous Cell Cancer+7 more
Rondo Therapeutics 149
Large-scale testing (Phase 3)Study completedNCT00680901
What this trial is testing

LOGiC - Lapatinib Optimization Study in ErbB2 (HER2) Positive Gastric Cancer: A Phase III Global, Blinded Study Designed to Evaluate Clinical Endpoints and Safety of Chemotherapy Plus Lapatinib

Who this might be right for
Neoplasms, Gastrointestinal Tract
Novartis Pharmaceuticals 545
Testing effectiveness (Phase 2)Looking for participantsNCT05702229
What this trial is testing

Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric Cancer
AstraZeneca 163
Testing effectiveness (Phase 2)UnknownNCT05216237
What this trial is testing

Evaluate the Efficacy and Safety of Sintilimab Plus Apatinib and Chemotherapy in Patients With HER-2 Negative Microsatellite Stability (MSS) Advanced or Metastatic Gastric (GC) or Gastroesophageal Junction (GEJ) Cancer

Who this might be right for
Gastric CancerChemotherapyImmunotherapy
Jiuda Zhao 31
Early research (Phase 1)Study completedNCT04805307
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy, Phase 1 Study of CMG901

Who this might be right for
Advanced Solid TumorGastric Cancer(Including Gastroesophageal Junction Adenocarcinoma)Pancreatic Cancer
Keymed Biosciences Co.Ltd 176
Testing effectiveness (Phase 2)Ended earlyNCT04363801
What this trial is testing

DKN-01 in Combination With Tislelizumab ± Chemotherapy in Patients With Gastric or Gastroesophageal Cancer

Who this might be right for
Gastric CancerGastric AdenocarcinomaGastroEsophageal Cancer
Leap Therapeutics, Inc. 247
Large-scale testing (Phase 3)Looking for participantsNCT06123494
What this trial is testing

SHR-A1811 for Subjects With Her2-positive Gastric Cancer and Gastroesophageal Junction Adenocarcinoma After Progression on or After First-line Anti-HER2 Therapy-containing Regimen

Who this might be right for
HER2-positive Advanced Gastric Cancer or Gastroesophageal Junction Adenocarcinoma
Jiangsu HengRui Medicine Co., Ltd. 360
Early research (Phase 1)Study completedNCT03849469
What this trial is testing

XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors

Who this might be right for
MelanomaCervical CarcinomaPancreatic Carcinoma+20 more
Xencor, Inc. 78
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