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Results for “Advanced or Metastatic Hepatocellular Carcinoma”

174 trials

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Showing 20 of 174 results

Not applicableLooking for participantsNCT06887348
What this trial is testing

Assess the Long-term Safety Outcomes in Patients Previously Treated With RP1, RP2, or RP3

Who this might be right for
MelanomaMetastatic MelanomaAdvanced Solid Tumor+1 more
Replimune Inc. 50
Testing effectiveness (Phase 2)Looking for participantsNCT07227012
What this trial is testing

Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

Who this might be right for
Carcinoma, HepatocellularHepatocellular CancerHepatocellular Carcinoma+4 more
Pfizer 138
Testing effectiveness (Phase 2)Study completedNCT00940225
What this trial is testing

Study of Cabozantinib (XL184) in Adults With Advanced Malignancies

Who this might be right for
Solid TumorsCancer
Exelixis 730
Testing effectiveness (Phase 2)Ended earlyNCT02575339
What this trial is testing

MLN0128 Compared to Sorafenib in Advanced or Metastatic Hepatocellular Carcinoma

Who this might be right for
Hepatocellular CarcinomaLiver CancerHCC
Kathy Miller 11
Testing effectiveness (Phase 2)Study completedNCT00003557
What this trial is testing

Dolastatin 10 in Treating Patients With Metastatic Or Recurrent Liver, Bile Duct, or Gallbladder Cancer

Who this might be right for
Extrahepatic Bile Duct CancerGallbladder CancerLiver Cancer
University of Chicago 16
Not applicableUnknownNCT03340636
What this trial is testing

Residual Plasma Concentration of Sorafenib and Adverse Events in CHC

Who this might be right for
Advanced or Metastatic Hepatocellular Carcinoma
University Hospital, Caen 60
Testing effectiveness (Phase 2)Study completedNCT00003907
What this trial is testing

Chemoembolization in Treating Patients With Primary Liver Cancer or Metastases to the Liver

Who this might be right for
Liver CancerMetastatic Cancer
Eastern Cooperative Oncology Group 50
Early research (Phase 1)Study completedNCT02572687
What this trial is testing

Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies

Who this might be right for
Gastric CancerGastroesophageal Junction AdenocarcinomaNon-Small Cell Lung Cancer+1 more
Eli Lilly and Company 85
Early research (Phase 1)Looking for participantsNCT06427941
What this trial is testing

BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Metastatic Hepatocellular CarcinomaLocal Advanced Hepatocellular CarcinomaAlpha-fetoprotein (AFP)-Producing Gastric Cancer+2 more
BeOne Medicines 140
Early research (Phase 1)Temporarily pausedNCT06968195
What this trial is testing

Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma

Who this might be right for
Advanced Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaRecurrent Hepatocellular Carcinoma+3 more
Roswell Park Cancer Institute 24
Early research (Phase 1)Study completedNCT00005842
What this trial is testing

Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer

Who this might be right for
Cancer
National Cancer Institute (NCI) 24
Early research (Phase 1)Active Not RecruitingNCT03983954
What this trial is testing

Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumor, Including a Cohort Expansion in Esophageal Cancer.

Who this might be right for
ER+ Breast CancerOvarian CancerCervical Squamous Cell Carcinoma+17 more
NeoTX Therapeutics Ltd. 120
Early research (Phase 1)WithdrawnNCT03217253
What this trial is testing

Tazemetostat in Treating Patients With Metastatic or Unresectable Solid Tumors or B-Cell Lymphomas With Liver Dysfunction

Who this might be right for
Ann Arbor Stage III B-Cell Non-Hodgkin LymphomaAnn Arbor Stage IV B-Cell Non-Hodgkin LymphomaMetastatic Malignant Solid Neoplasm+8 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Looking for participantsNCT05733598
What this trial is testing

Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

Who this might be right for
Hepatocellular CarcinomaBiliary Tract Cancer
Replimune Inc. 60
Testing effectiveness (Phase 2)Looking for participantsNCT05440708
What this trial is testing

TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Tvardi Therapeutics, Incorporated 178
Testing effectiveness (Phase 2)Ended earlyNCT03422679
What this trial is testing

Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies

Who this might be right for
Breast CancerColorectal CancerAdenoid Cystic Carcinoma+5 more
Cellestia Biotech AG 79
Early research (Phase 1)Active Not RecruitingNCT03170960
What this trial is testing

Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Urothelial CarcinomaRenal Cell CarcinomaNon-Small Cell Lung Cancer+11 more
Exelixis 914
Very early researchUnknownNCT03965546
What this trial is testing

ET 140202 -T Cell Combined With TAE or Sorafenib in the Treatment of Liver Cancer

Who this might be right for
Hepatocellular CarcinomaLiver CancerLiver Neoplasms+1 more
First Affiliated Hospital Xi'an Jiaotong University 27
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07405086
What this trial is testing

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

Who this might be right for
Advanced Biliary Tract CarcinomaAdvanced Head and Neck Squamous Cell CarcinomaAdvanced Hepatocellular Carcinoma+18 more
OHSU Knight Cancer Institute 160
Testing effectiveness (Phase 2)WithdrawnNCT06690281
What this trial is testing

A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies

Who this might be right for
Gastrointestinal CarcinomaPancreatic CancerHepatocellular Cancer+5 more
National Cancer Institute (NCI)
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