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Results for “Alagille Syndrome”

31 trials

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Showing 20 of 31 results

Large-scale testing (Phase 3)Looking for participantsNCT05035030
What this trial is testing

Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome

Who this might be right for
Alagille Syndrome
Albireo, an Ipsen Company 70
Testing effectiveness (Phase 2)Study completedNCT02047318
What this trial is testing

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Subjects With Alagille Syndrome (ALGS)

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 19
Not applicableStudy completedNCT02131623
What this trial is testing

Validation of the Itch Reported Outcome (ItchRO) Diaries in Pediatric Cholestatic Liver Disease

Who this might be right for
Alagille SyndromeProgressive Familial Intrahepatic Cholestasis
Mirum Pharmaceuticals, Inc. 23
Early research (Phase 1)WithdrawnNCT01236586
What this trial is testing

RO4929097 in Children With Relapsed/Refractory Solid or CNS Tumors, Lymphoma, or T-Cell Leukemia

Who this might be right for
LymphomaBrain NeoplasmsSarcoma+2 more
National Cancer Institute (NCI)
Not applicableStudy completedNCT01515631
What this trial is testing

Characterization of Pulmonary Artery Stenoses in Alagille Syndrome - a Medical Record Review

Who this might be right for
Alagille Syndrome
Stanford University 25
Post-approval studies (Phase 4)Study completedNCT05488067
What this trial is testing

Atorvastatin Therapy on Xanthoma in Alagille Syndrome

Who this might be right for
Alagille SyndromeAtorvastatinXanthoma
Children's Hospital of Fudan University 15
Testing effectiveness (Phase 2)Study completedNCT04729751
What this trial is testing

Evaluate the Safety and Tolerability of Maralixibat in Infant Participants With Cholestatic Liver Diseases Including Progressive Familial Intrahepatic Cholestasis (PFIC) and Alagille Syndrome (ALGS).

Who this might be right for
Progressive Familial Intrahepatic CholestasisAlagille SyndromeCholestatic Liver Disease
Mirum Pharmaceuticals, Inc. 27
Not applicableLooking for participantsNCT06767605
What this trial is testing

Spanish Registry of Autoimmune and Cholestatic Liver Diseases (ColHai)

Who this might be right for
Hepatitis Autoimmune DiseasePrimary Biliary Cholangitis (PBC)Primary Sclerosing Cholangitis (PSC)+1 more
Asociación Española para el Estudio del Hígado 5,000
Not applicableApproved For MarketingNCT04530994
What this trial is testing

A Maralixibat Expanded Access Program for Patients With Cholestatic Pruritus Associated With Alagille Syndrome (ALGS)

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc.
Not applicableStudy completedNCT04666311
What this trial is testing

Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis

Who this might be right for
Pulmonary TuberculosisTuberculosis DiagnosisCovid-19+1 more
Klaus Reither 1,400
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07335523
What this trial is testing

Management of Steatorrhea in Children and Young Adults With Alagille Syndrome After Liver Transplantation

Who this might be right for
Steatorrhea
Digestive Care, Inc. 30
Not applicableUnknownNCT05846854
What this trial is testing

Decreasing Hemorrhage Risk in Children With Alagille Syndrome

Who this might be right for
Alagille SyndromePulmonary Artery StenosesAcquired Von Willebrand Disease
Stanford University 40
Not applicableStudy completedNCT00001642
What this trial is testing

Positional Cloning of the Gene(s) Responsible for Alagille Syndrome

Who this might be right for
Alagille Syndrome
National Human Genome Research Institute (NHGRI) 225
Not applicableLooking for participantsNCT06850038
What this trial is testing

A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment

Who this might be right for
Alagille Syndrome
Ipsen 30
Testing effectiveness (Phase 2)Study completedNCT02057692
What this trial is testing

Evaluation of LUM001 in the Reduction of Pruritus in Alagille Syndrome

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 37
Testing effectiveness (Phase 2)Study completedNCT02160782
What this trial is testing

Safety and Efficacy Study of LUM001 (Maralixibat) With a Drug Withdrawal Period in Participants With Alagille Syndrome (ALGS)

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 31
Early research (Phase 1)Study completedNCT02963077
What this trial is testing

A Safety and Pharmakokinetic Study of A4250 Alone or in Combination With A3384

Who this might be right for
Orphan Cholestatic Liver DiseasesPrimary Biliary CirrhosisProgressive Familial Intrahepatic Cholestasis+1 more
Albireo 94
Testing effectiveness (Phase 2)Study completedNCT02117713
What this trial is testing

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Pediatric Subjects With Alagille Syndrome

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 34
Post-approval studies (Phase 4)Looking for participantsNCT07290257
What this trial is testing

Long-Term Low-Intervention SafEty and Clinical Outcomes Clinical Study of LivmArli® in Patients With Alagille Syndrome in the European Union (LEAP-EU)

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 100
Early research (Phase 1)Study completedNCT03082937
What this trial is testing

An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects

Who this might be right for
Orphan Cholestatic Liver DiseasesProgressive Familial Intrahepatic CholestasisAlagille Syndrome+1 more
Albireo 6
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