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Results for “Alagille Syndrome”

30 trials

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Showing 20 of 30 results

Testing effectiveness (Phase 2)Study completedNCT04729751
What this trial is testing

Evaluate the Safety and Tolerability of Maralixibat in Infant Participants With Cholestatic Liver Diseases Including Progressive Familial Intrahepatic Cholestasis (PFIC) and Alagille Syndrome (ALGS).

Who this might be right for
Progressive Familial Intrahepatic CholestasisAlagille SyndromeCholestatic Liver Disease
Mirum Pharmaceuticals, Inc. 27
Testing effectiveness (Phase 2)Study completedNCT02047318
What this trial is testing

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Subjects With Alagille Syndrome (ALGS)

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 19
Post-approval studies (Phase 4)Looking for participantsNCT07290257
What this trial is testing

Long-Term Low-Intervention SafEty and Clinical Outcomes Clinical Study of LivmArli® in Patients With Alagille Syndrome in the European Union (LEAP-EU)

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 100
Not applicableLooking for participantsNCT06767605
What this trial is testing

Spanish Registry of Autoimmune and Cholestatic Liver Diseases (ColHai)

Who this might be right for
Hepatitis Autoimmune DiseasePrimary Biliary Cholangitis (PBC)Primary Sclerosing Cholangitis (PSC)+1 more
Asociación Española para el Estudio del Hígado 5,000
Not applicableUnknownNCT05846854
What this trial is testing

Decreasing Hemorrhage Risk in Children With Alagille Syndrome

Who this might be right for
Alagille SyndromePulmonary Artery StenosesAcquired Von Willebrand Disease
Stanford University 40
Not applicableStudy completedNCT00001642
What this trial is testing

Positional Cloning of the Gene(s) Responsible for Alagille Syndrome

Who this might be right for
Alagille Syndrome
National Human Genome Research Institute (NHGRI) 225
Large-scale testing (Phase 3)Looking for participantsNCT05035030
What this trial is testing

Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome

Who this might be right for
Alagille Syndrome
Albireo, an Ipsen Company 70
Testing effectiveness (Phase 2)Study completedNCT01903460
What this trial is testing

Safety and Efficacy Study of LUM001 in the Treatment of Cholestatic Liver Disease in Patients With Alagille Syndrome

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 20
Testing effectiveness (Phase 2)Study completedNCT02057692
What this trial is testing

Evaluation of LUM001 in the Reduction of Pruritus in Alagille Syndrome

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 37
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07335523
What this trial is testing

Management of Steatorrhea in Children and Young Adults With Alagille Syndrome After Liver Transplantation

Who this might be right for
Steatorrhea
Digestive Care, Inc. 30
Not applicableStudy completedNCT01515631
What this trial is testing

Characterization of Pulmonary Artery Stenoses in Alagille Syndrome - a Medical Record Review

Who this might be right for
Alagille Syndrome
Stanford University 25
Not applicableLooking for participantsNCT06850038
What this trial is testing

A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment

Who this might be right for
Alagille Syndrome
Ipsen 30
Not applicableTemporarily pausedNCT00571272
What this trial is testing

Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC)

Who this might be right for
Liver DiseasesAlagille SyndromeAlpha 1-Antitrypsin Deficiency
Arbor Research Collaborative for Health 1,675
Large-scale testing (Phase 3)Study completedNCT05543174
What this trial is testing

TAK-625 for the Treatment of Alagille Syndrome (ALGS)

Who this might be right for
Alagille Syndrome (ALGS)
Takeda 7
Not applicableNot Yet RecruitingNCT07293897
What this trial is testing

A Database Study of Maralixibat (TAK-625) in Participants With Alagille Syndrome (ALGS) and Progressive Familial Intrahepatic Cholestasis (PFIC)

Who this might be right for
Alagille Syndrome (ALGS)Progressive Familial Intrahepatic Cholestasis (PFIC)
Takeda 50
Early research (Phase 1)Study completedNCT02963077
What this trial is testing

A Safety and Pharmakokinetic Study of A4250 Alone or in Combination With A3384

Who this might be right for
Orphan Cholestatic Liver DiseasesPrimary Biliary CirrhosisProgressive Familial Intrahepatic Cholestasis+1 more
Albireo 94
Testing effectiveness (Phase 2)Study completedNCT02160782
What this trial is testing

Safety and Efficacy Study of LUM001 (Maralixibat) With a Drug Withdrawal Period in Participants With Alagille Syndrome (ALGS)

Who this might be right for
Alagille Syndrome
Mirum Pharmaceuticals, Inc. 31
Early research (Phase 1)WithdrawnNCT01236586
What this trial is testing

RO4929097 in Children With Relapsed/Refractory Solid or CNS Tumors, Lymphoma, or T-Cell Leukemia

Who this might be right for
LymphomaBrain NeoplasmsSarcoma+2 more
National Cancer Institute (NCI)
Not applicableNot Yet RecruitingNCT06506734
What this trial is testing

Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia

Who this might be right for
Dental Diseases
University Hospital, Toulouse 120
Not applicableStudy completedNCT02131623
What this trial is testing

Validation of the Itch Reported Outcome (ItchRO) Diaries in Pediatric Cholestatic Liver Disease

Who this might be right for
Alagille SyndromeProgressive Familial Intrahepatic Cholestasis
Mirum Pharmaceuticals, Inc. 23
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