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Results for “Alpha-Mannosidase Deficiency”

29 trials

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Showing 20 of 29 results

Large-scale testing (Phase 3)Study completedNCT01681953
What this trial is testing

A Placebo-Controlled Phase 3 Trial of Repeated Lamazym Treatment of Subjects With Alpha-Mannosidosis

Who this might be right for
Alpha-Mannosidosis
Zymenex A/S 25
Not applicableUnknownNCT00005900
What this trial is testing

Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Who this might be right for
I Cell DiseaseFucosidosisGloboid Cell Leukodystrophy+9 more
Fairview University Medical Center 10
Large-scale testing (Phase 3)Study completedNCT01908725
What this trial is testing

Lamazym Aftercare Study

Who this might be right for
Alpha-Mannosidosis
Chiesi Farmaceutici S.p.A. 8
Testing effectiveness (Phase 2)Ended earlyNCT00668564
What this trial is testing

Hematopoietic Stem Cell Transplantation (HCT) for Inborn Errors of Metabolism

Who this might be right for
Hurler's SyndromeMaroteaux-Lamy SyndromeSly Syndrome+8 more
Masonic Cancer Center, University of Minnesota 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT02171104
What this trial is testing

MT2013-31: Allo HCT for Metabolic Disorders and Severe Osteopetrosis

Who this might be right for
Mucopolysaccharidosis DisordersHurler SyndromeHunter Syndrome+26 more
Masonic Cancer Center, University of Minnesota 149
Not applicableStudy completedNCT01891422
What this trial is testing

Longitudinal Studies of the Glycoproteinoses

Who this might be right for
AspartylglucosaminuriaFucosidosisGalactosialidosis+6 more
Greenwood Genetic Center 100
Not applicableAvailableNCT04959240
What this trial is testing

Expanded Access to Velmanase Alfa

Who this might be right for
Alpha-Mannosidosis
Chiesi Farmaceutici S.p.A.
Testing effectiveness (Phase 2)Study completedNCT02998879
What this trial is testing

Trial on Safety and Efficacy of Velmanase Alfa Treatment in Pediatric Patients With Alpha-Mannosidosis

Who this might be right for
Alpha-Mannosidosis
Chiesi Farmaceutici S.p.A. 5
Testing effectiveness (Phase 2)Ended earlyNCT01372228
What this trial is testing

Phase I/II Pilot Study of Mixed Chimerism to Treat Inherited Metabolic Disorders

Who this might be right for
Hurler Syndrome (MPS I)Hurler-Scheie SyndromeHunter Syndrome (MPS II)+9 more
Talaris Therapeutics Inc. 3
Not applicableStudy completedNCT00498420
What this trial is testing

The Natural History of Alpha-Mannosidosis

Who this might be right for
Alpha Mannosidosis
Zymenex A/S 45
Early research (Phase 1)Study completedNCT01268358
What this trial is testing

Safety Study of Recombinant Human Alpha-mannosidase for the Treatment of Patients With Alpha-mannosidosis

Who this might be right for
Alpha Mannosidosis
Zymenex A/S 10
Large-scale testing (Phase 3)WithdrawnNCT04031066
What this trial is testing

Interventional Study to Assess Efficacy and Safety of Velmanase Alfa in Patients With Alpha Mannosidosis

Who this might be right for
Alpha-Mannosidosis
Chiesi Farmaceutici S.p.A.
Testing effectiveness (Phase 2)Study completedNCT01043640
What this trial is testing

Allogeneic Bone Marrow Transplant for Inherited Metabolic Disorders

Who this might be right for
MucopolysaccharidosisHurler SyndromeHunter Syndrome+10 more
Masonic Cancer Center, University of Minnesota 46
Not applicableEnded earlyNCT03651245
What this trial is testing

European Alpha-Mannosidosis Participant

Who this might be right for
ImmunodeficiencySkeletal AbnormalitiesDeafness+3 more
CENTOGENE GmbH Rostock 667
Not applicableWithdrawnNCT03264040
What this trial is testing

Biomarker for Mannosidosis Disease (BioMannosidosis)

Who this might be right for
Alpha-Mannosidase B DeficiencyLysosomal Alpha B MannosidosisAlpha-Mannosidase Deficiency
CENTOGENE GmbH Rostock
Large-scale testing (Phase 3)Study completedNCT02478840
What this trial is testing

Evaluation of Long-term Efficacy of Treatment With Lamazym

Who this might be right for
Alpha-Mannosidosis
Zymenex A/S 18
Testing effectiveness (Phase 2)Looking for participantsNCT01962415
What this trial is testing

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more
Paul Szabolcs 100
Not applicableLooking for participantsNCT04528355
What this trial is testing

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+2 more
Paul Szabolcs 50
Not applicableLooking for participantsNCT03333200
What this trial is testing

Longitudinal Study of Neurodegenerative Disorders

Who this might be right for
MLDKrabbe DiseaseALD+24 more
University of Pittsburgh 1,500
Early research (Phase 1)Looking for participantsNCT02254863
What this trial is testing

UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells

Who this might be right for
AdrenoleukodystrophyBatten DiseaseMucopolysaccharidosis II+9 more
Joanne Kurtzberg, MD 40
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