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Results for “Alpha-Mannosidosis”

29 trials

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Showing 20 of 29 results

Not applicableLooking for participantsNCT06184503
What this trial is testing

Analysis of Velmanase Alfa (Lamzede®)'s Effects in the Body of Children With Alpha-Mannosidosis Under the Age 3

Who this might be right for
Alpha-Mannosidosis
Chiesi Farmaceutici S.p.A. 5
Not applicableEnded earlyNCT03651245
What this trial is testing

European Alpha-Mannosidosis Participant

Who this might be right for
ImmunodeficiencySkeletal AbnormalitiesDeafness+3 more
CENTOGENE GmbH Rostock 667
Testing effectiveness (Phase 2)Study completedNCT03513328
What this trial is testing

Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation

Who this might be right for
Bone Marrow Failure SyndromeThalassemiaSickle Cell Disease+13 more
University of Florida 6
Testing effectiveness (Phase 2)UnknownNCT01285700
What this trial is testing

Dose Finding Study of Recombinant Human Alpha-mannosidase for the Treatment of Patients With Alpha-mannosidosis

Who this might be right for
Alpha Mannosidosis
Zymenex A/S 10
Not applicableLooking for participantsNCT03333200
What this trial is testing

Longitudinal Study of Neurodegenerative Disorders

Who this might be right for
MLDKrabbe DiseaseALD+24 more
University of Pittsburgh 1,500
Testing effectiveness (Phase 2)Study completedNCT00176917
What this trial is testing

Stem Cell Transplantation for Hurler

Who this might be right for
Mucopolysaccharidosis IMucopolysaccharidosis VIMannosidosis+1 more
Masonic Cancer Center, University of Minnesota 41
Testing effectiveness (Phase 2)Ended earlyNCT01372228
What this trial is testing

Phase I/II Pilot Study of Mixed Chimerism to Treat Inherited Metabolic Disorders

Who this might be right for
Hurler Syndrome (MPS I)Hurler-Scheie SyndromeHunter Syndrome (MPS II)+9 more
Talaris Therapeutics Inc. 3
Early research (Phase 1)Study completedNCT01268358
What this trial is testing

Safety Study of Recombinant Human Alpha-mannosidase for the Treatment of Patients With Alpha-mannosidosis

Who this might be right for
Alpha Mannosidosis
Zymenex A/S 10
Testing effectiveness (Phase 2)Study completedNCT01681940
What this trial is testing

Long-term Efficacy and Safety of Lamazym for the Treatment of Patients With Alpha-Mannosidosis

Who this might be right for
Alpha-Mannosidosis
Zymenex A/S 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT02171104
What this trial is testing

MT2013-31: Allo HCT for Metabolic Disorders and Severe Osteopetrosis

Who this might be right for
Mucopolysaccharidosis DisordersHurler SyndromeHunter Syndrome+26 more
Masonic Cancer Center, University of Minnesota 149
Large-scale testing (Phase 3)Ended earlyNCT00654433
What this trial is testing

ALD-101 Adjuvant Therapy of Unrelated Umbilical Cord Blood Transfusion (UCBT) in Patients With Inherited Metabolic Diseases

Who this might be right for
Inherited Metabolic DiseasesLysosomal Storage DisordersPeroxisomal Storage Diseases+2 more
Aldagen 40
Large-scale testing (Phase 3)Study completedNCT02478840
What this trial is testing

Evaluation of Long-term Efficacy of Treatment With Lamazym

Who this might be right for
Alpha-Mannosidosis
Zymenex A/S 18
Testing effectiveness (Phase 2)Looking for participantsNCT01962415
What this trial is testing

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more
Paul Szabolcs 100
Large-scale testing (Phase 3)WithdrawnNCT04031066
What this trial is testing

Interventional Study to Assess Efficacy and Safety of Velmanase Alfa in Patients With Alpha Mannosidosis

Who this might be right for
Alpha-Mannosidosis
Chiesi Farmaceutici S.p.A.
Large-scale testing (Phase 3)Study completedNCT01681953
What this trial is testing

A Placebo-Controlled Phase 3 Trial of Repeated Lamazym Treatment of Subjects With Alpha-Mannosidosis

Who this might be right for
Alpha-Mannosidosis
Zymenex A/S 25
Not applicableAvailableNCT04959240
What this trial is testing

Expanded Access to Velmanase Alfa

Who this might be right for
Alpha-Mannosidosis
Chiesi Farmaceutici S.p.A.
Large-scale testing (Phase 3)Study completedNCT01908712
What this trial is testing

Lamazym Aftercare Study FR Designed to Provide Treatment for French Patients

Who this might be right for
Alpha-Mannosidosis
Chiesi Farmaceutici S.p.A. 13
Not applicableLooking for participantsNCT04528355
What this trial is testing

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+2 more
Paul Szabolcs 50
Not applicableStudy completedNCT02141503
What this trial is testing

Clinical Biomarkers in Alpha-mannosidosis

Who this might be right for
Alpha-Mannosidosis
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 11
Not applicableStudy completedNCT01891422
What this trial is testing

Longitudinal Studies of the Glycoproteinoses

Who this might be right for
AspartylglucosaminuriaFucosidosisGalactosialidosis+6 more
Greenwood Genetic Center 100
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