Early research (Phase 1)Study completedNCT04208152What this trial is testingA First-in-Human Study of Single and Multiple Doses of anle138b in Healthy SubjectsWho this might be right forHealthy Volunteers MODAG GmbH 68
Not applicableUnknownNCT03133611What this trial is testingDetecting Parkinson's Disease Through Speech AnalysisWho this might be right forParkinson DiseaseREM Sleep Behavior Disorder Czech Technical University in Prague 350
Not applicableLooking for participantsNCT07533799What this trial is testingThe Swedish BioFINDER Sleep StudyWho this might be right forParkinson´s DiseaseREM Sleep Behavior Disorder (iRBD)Lewy Body Disease+2 more Skane University Hospital 650
Not applicableStudy completedNCT05638815What this trial is testingAn Observational Study of Parkinson's Disease and Other Synucleinopathies (EASE-PD)Who this might be right forParkinson's DiseaseMultiple System Atrophy SciNeuro 89
Not applicableEnded earlyNCT04020198What this trial is testingA Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With SynucleinopathiesWho this might be right forParkinson DiseaseMultiple System AtrophyRapid Eye Movement Sleep Behavior Disorder+1 more Stony Brook University 8
Not applicableStudy completedNCT04700722What this trial is testingSynuclein-One StudyWho this might be right forParkinson DiseaseMultiple System AtrophyDementia With Lewy Bodies+1 more CND Life Sciences 428
Not applicableLooking for participantsNCT05353959What this trial is testingProgression Follow up of the First-degree Relatives of Patients With REM Sleep Behavior DisorderWho this might be right forParkinson Disease Chinese University of Hong Kong 400
Not applicableStudy completedNCT03156647What this trial is testingAlpha-synuclein Level in Saliva to Differentiate Between Idiopathic Parkinson Disease and Iatrogenic Parkinsonian SyndromeWho this might be right forParkinson DiseaseParkinsonian Disorders Centre Hospitalier Universitaire de Nīmes 80
Very early researchStudy completedNCT06445465What this trial is testingStudy to Evaluate a Potential PET Radioligand for Imaging Alpha-synuclein Deposits in the BrainWho this might be right forAlpha-SynucleinopathyParkinson's DiseaseDementia With Lewy Bodies+1 more Invicro 12
Not applicableNot Yet RecruitingNCT07474779What this trial is testingUnderstanding Alpha-Synuclein Spread in Parkinson's Disease Through Blood Biomarkers and NeuroimagingWho this might be right forParkinson's Disease (PD)GBA1 Parkinson DiseaseREM Sleep Behavior Disorder (iRBD) University of Pavia 160
Not applicableLooking for participantsNCT07324330What this trial is testingSlowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical ActivityWho this might be right forParkinson DiseaseProdromal StageNeurodegenerative Diseases+7 more University Hospital, Bonn 130
Not applicableLooking for participantsNCT06528964What this trial is testingProteinopathies Expression in Skin of Neurodegenerative DisordersWho this might be right forAlzheimer DiseaseFrontotemporal DementiaParkinson Disease+3 more Universidad Autonoma de San Luis Potosí 40
Not applicableLooking for participantsNCT05986643What this trial is testingBrain Training to Improve Balance in Parkinson's DiseaseWho this might be right forParkinson Disease University of Leicester 100
Early research (Phase 1)Study completedNCT04685265What this trial is testingAssess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of anle138b in Parkinson's DiseaseWho this might be right forParkinson Disease MODAG GmbH 70
Not applicableUnknownNCT02114242What this trial is testingBiomarkers in Parkinsonian SyndromesWho this might be right forParkinsonian SyndromesParkinson's DiseaseMultiple System Atrophy+1 more University Hospital, Bordeaux 100
Not applicableStudy completedNCT06738862What this trial is testing[18F] - FD17 PET Imaging of α-synuclein: A Clinical Study in α-synucleinopathy PatientsWho this might be right forα-synucleinopathyParkinson's Disease (PD)Multiple System Atrophy+2 more Ruijin Hospital 55
Not applicableUnknownNCT04264273What this trial is testingDiagnosis of Parkinson´s Disease by Means of Submandibular Gland Needle BiopsyWho this might be right forParkinson Disease Universität des Saarlandes 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06996652What this trial is testingAn Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)Who this might be right forREM Sleep Behavior Disorder Yale University 108
Not applicableUnknownNCT04062279What this trial is testingPredictors of Parkinson's Disease ProgressionWho this might be right forParkinson DiseaseCognitive DysfunctionBiomarkers Ain Shams University 100
Early research (Phase 1)Study completedNCT05532358What this trial is testingA Drug-Drug Interaction Study to Assess the CYP1A2 and CYP3A4 Interaction Potential of TEV-56286 (anle138b)Who this might be right forHealthy Volunteers MODAG GmbH 54