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Results for “Amaurosis of Leber”

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Showing 11 of 0 results

Testing effectiveness (Phase 2)Study completedNCT03140969
What this trial is testing

Study to Evaluate QR-110 in Leber's Congenital Amaurosis (LCA) Due to the c.2991+1655A>G Mutation (p.Cys998X) in the CEP290 Gene

Who this might be right for
Leber's Congenital Amaurosis
Laboratoires Thea 11
Early research (Phase 1)Study completedNCT01014052
What this trial is testing

Safety/Proof of Concept Study of Oral QLT091001 in Subjects With Leber Congenital Amaurosis (LCA) or Retinitis Pigmentosa (RP) Due to Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT) Mutations

Who this might be right for
LCA (Leber Congenital Amaurosis)RP (Retinitis Pigmentosa)
QLT Inc. 32
Not applicableStudy completedNCT02575430
What this trial is testing

Natural History Study in Inherited Retinal Disease Subjects Caused by Mutations in RPE65 or LRAT

Who this might be right for
Leber Congenital Amaurosis (LCA)Retinitis Pigmentosa (RP)
QLT Inc. 59
Not applicableStudy completedNCT02714816
What this trial is testing

Natural History Study of Patients With Leber Congenital Amaurosis Associated With Mutations in RPE65

Who this might be right for
Leber Congenital Amaurosis
MeiraGTx UK II Ltd 37
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07681778
What this trial is testing

Safety and Tolerability of Subretinal OPGx-RDH12-1001 for LCA-Associated Inherited Retinal Degeneration (LCA-IRD)

Who this might be right for
Leber Congenital AmaurosisLeber Congenital Amaurosis (LCA)
Opus Genetics, Inc 10
Testing effectiveness (Phase 2)Study completedNCT00643747
What this trial is testing

Safety Study of RPE65 Gene Therapy to Treat Leber Congenital Amaurosis

Who this might be right for
Retinal Degeneration
University College, London 12
Testing effectiveness (Phase 2)Ended earlyNCT03913130
What this trial is testing

Extension Study to Study PQ-110-001 (NCT03140969)

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more
Laboratoires Thea 9
Not applicableStudy completedNCT03396042
What this trial is testing

Natural History Study of CEP290-Related Retinal Degeneration

Who this might be right for
BlindnessLeber Congenital Amaurosis 10Vision Disorders+5 more
Editas Medicine, Inc. 26
Large-scale testing (Phase 3)Active Not RecruitingNCT03913143
What this trial is testing

Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE)

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more
ProQR Therapeutics 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT01208389
What this trial is testing

Phase 1 Follow-on Study of AAV2-hRPE65v2 Vector in Subjects With Leber Congenital Amaurosis (LCA) 2

Who this might be right for
Leber Congenital Amaurosis
Spark Therapeutics, Inc. 12
Not applicableStudy completedNCT00422721
What this trial is testing

Genetic Study of Patients Suffering From Congenital Amaurosis of Leber or From an Early Severe Retinal Dystrophy

Who this might be right for
AmaurosisRetinal Diseases
Nantes University Hospital 360