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Results for “Amyloid”

1,303 trials

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Showing 20 of 1,303 results

Early research (Phase 1)Active Not RecruitingNCT03283917
What this trial is testing

Daratumumab, Ixazomib, and Dexamethasone in AL Amyloidosis

Who this might be right for
Newly Diagnosed Primary AmyloidosisRecurrent Primary AmyloidosisRefractory Primary Amyloidosis
M.D. Anderson Cancer Center 21
Testing effectiveness (Phase 2)Ended earlyNCT02590588
What this trial is testing

Idelalisib for Immunoglobulin M (IgM)-Associated Primary (AL) Amyloidosis

Who this might be right for
Amyloidosis
John Mark Sloan 1
Early research (Phase 1)Looking for participantsNCT05652335
What this trial is testing

JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

Who this might be right for
Relapsed or Refractory Multiple MyelomaPreviously Treated Amyloid Light-chain (AL) Amyloidosis
Janssen Research & Development, LLC 180
Testing effectiveness (Phase 2)Study completedNCT00722046
What this trial is testing

Multiple IV Dose Study Of PF-04360365 In Patients With Mild To Moderate Alzheimer's Disease

Who this might be right for
Alzheimer's Disease
Pfizer 198
Large-scale testing (Phase 3)Active Not RecruitingNCT06194825
What this trial is testing

EPIC-ATTR: A Study to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-term Safety in Chinese Subjects With Transthyretin Amyloid Cardiomyopathy

Who this might be right for
Transthyretin Amyloid Cardiomyopathy
AstraZeneca 64
Testing effectiveness (Phase 2)Ended earlyNCT02201524
What this trial is testing

Study to Evaluate PF-04965842 in Patients With Moderate to Severe Psoriasis

Who this might be right for
Plaque Psoriasis
Pfizer 59
Testing effectiveness (Phase 2)Study completedNCT01097096
What this trial is testing

Safety, Tolerability and Abeta-specific Antibody Response of Repeated i.m. Injections of Adjuvanted CAD106 in Mild Alzheimer Patients

Who this might be right for
Alzheimer's Disease
Novartis Pharmaceuticals 177
Not applicableLooking for participantsNCT07402356
What this trial is testing

VR Pupillometry in Cognitive Impairment

Who this might be right for
Alzheimer s DiseaseMajor Depressive Disorder (MDD)Mild Cognitive Impairment+1 more
Max-Planck-Institute of Psychiatry 140
Not applicableStudy completedNCT01425957
What this trial is testing

Identification of Biomarkers Sensitive to Disease Progression in Patients With Mild Cognitive Impairment

Who this might be right for
MILD COGNITIVE IMPAIRMENT
Qualissima 229
Not applicableLooking for participantsNCT03507257
What this trial is testing

Longitudinal Early-onset Alzheimer's Disease Study Protocol

Who this might be right for
Early Onset Alzheimer DiseaseAlzheimer DiseaseMild Cognitive Impairment
Indiana University 850
Large-scale testing (Phase 3)Study completedNCT01994889
What this trial is testing

Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
Pfizer 441
Not applicableUnknownNCT05701397
What this trial is testing

Prevalence of Cardiac Amyloidosis in Patients Undergoing Surgery for Lumbar Spinal Stenosis.

Who this might be right for
Cardiac AmyloidosisSpinal Stenosis
Steen Hvitfeldt Poulsen 200
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06470061
What this trial is testing

RQC for the Prevention of Alzheimer's Disease and Retinal Amyloid-β

Who this might be right for
Alzheimer DiseaseMild Cognitive ImpairmentCognitive Decline
Zaparackas and Knepper LTD 200
Not applicableStudy completedNCT02770872
What this trial is testing

The Association of SAA With Apolipoprotein B Affects Cardiovascular Risk

Who this might be right for
Cardiovascular Disease
Lisa Tannock 19
Not applicableLooking for participantsNCT06539169
What this trial is testing

FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases

Who this might be right for
Alpha-ThalassemiaBeta-ThalassemiaAmyloidosis+14 more
xCures 1,000
Not applicableNot Yet RecruitingNCT07544953
What this trial is testing

Amyloid Monoclonal Antibody Treatment in PD Patients With Coexistent AD Pathology

Who this might be right for
Parkinson Disease
Yonsei University 60
Not applicableStudy completedNCT05795400
What this trial is testing

Administration of the SGLT-2 Inhibitor Dapagliflozin in the Patients With Amyloid Cardiomyopathy

Who this might be right for
Heart Failure With Reduced Ejection FractionHeart Failure With Preserved Ejection FractionHeart Failure With Mid Range Ejection Fraction+1 more
National Medical Research Center for Cardiology, Ministry of Health of Russian Federation 50
Not applicableLooking for participantsNCT06866912
What this trial is testing

Observational Epidemiological Study of Patients Suffering From Systemic Amyloidosis

Who this might be right for
Cardiomyopathy
IRCCS Azienda Ospedaliero-Universitaria di Bologna 750
Early research (Phase 1)Study completedNCT01814839
What this trial is testing

A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC (Revusiran) in Healthy Volunteers

Who this might be right for
TTR-mediated Amyloidosis
Alnylam Pharmaceuticals 85
Large-scale testing (Phase 3)Study completedNCT03542656
What this trial is testing

Application of Amyloid PET in Cerebral Amyloid Angiopathy

Who this might be right for
Cerebral Amyloid AngiopathyIntracranial HemorrhagesAlzheimer Disease
National Taiwan University Hospital 160
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