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Results for “Amyloid Neuropathies, Familial”

180 trials

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Showing 20 of 180 results

Large-scale testing (Phase 3)Study completedNCT01994889
What this trial is testing

Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
Pfizer 441
Not applicableUnknownNCT05701397
What this trial is testing

Prevalence of Cardiac Amyloidosis in Patients Undergoing Surgery for Lumbar Spinal Stenosis.

Who this might be right for
Cardiac AmyloidosisSpinal Stenosis
Steen Hvitfeldt Poulsen 200
Not applicableStudy completedNCT05795400
What this trial is testing

Administration of the SGLT-2 Inhibitor Dapagliflozin in the Patients With Amyloid Cardiomyopathy

Who this might be right for
Heart Failure With Reduced Ejection FractionHeart Failure With Preserved Ejection FractionHeart Failure With Mid Range Ejection Fraction+1 more
National Medical Research Center for Cardiology, Ministry of Health of Russian Federation 50
Not applicableLooking for participantsNCT06866912
What this trial is testing

Observational Epidemiological Study of Patients Suffering From Systemic Amyloidosis

Who this might be right for
Cardiomyopathy
IRCCS Azienda Ospedaliero-Universitaria di Bologna 750
Not applicableLooking for participantsNCT07196839
What this trial is testing

Determining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker Study

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
University of Texas Southwestern Medical Center 50
Not applicableStudy completedNCT04862273
What this trial is testing

CMR T1 Mapping for Diagnosis of Cardiac Amyloidosis

Who this might be right for
Heart Failure NYHA Class IIHeart Failure NYHA Class IIIHeart Failure NYHA Class IV+4 more
University of Leipzig 112
Testing effectiveness (Phase 2)Study completedNCT02595983
What this trial is testing

The Study of an Investigational Drug, Revusiran (ALN-TTRSC), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Whose Disease Has Continued to Worsen Following Liver Transplant

Who this might be right for
Transthyretin (TTR)-Mediated AmyloidosisFamilial Amyloidotic Polyneuropathy (FAP)ATTR Amyloidosis+1 more
Alnylam Pharmaceuticals 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT03536767
What this trial is testing

Open-Label Study of AG10 in Patients with Cardiomyopathy

Who this might be right for
Amyloid Cardiomyopathy
Eidos Therapeutics, a BridgeBio company 55
Not applicableLooking for participantsNCT07382128
What this trial is testing

Myocardial Perfusion CMR for Differentiating and Characterizing Hypertrophic Cardiomyopathy Phenotypes

Who this might be right for
HCM - Hypertrophic CardiomyopathyAnderson Fabry DiseaseCardiac Magnetic Resonance Imaging+1 more
IRCCS Azienda Ospedaliero-Universitaria di Bologna 250
Not applicableUnknownNCT03984877
What this trial is testing

Impact of Amyloidosis on TAVI Patients

Who this might be right for
Valve Stenoses, AorticAmyloidosis Cardiac
Javier López Pais 320
Not applicableLooking for participantsNCT06096675
What this trial is testing

CAPACITY (Cardiac Amyloidosis and Physical ACtivITY) Study

Who this might be right for
Cardiac Amyloidosis
Wake Forest University Health Sciences 50
Not applicableLooking for participantsNCT05697861
What this trial is testing

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
Post-approval studies (Phase 4)Ended earlyNCT03040427
What this trial is testing

The Role of F-18 Florbetapir in the Early Detection of Cardiac Amyloidosis

Who this might be right for
Cardiac Amyloidosis
The Cleveland Clinic 12
Not applicableUnknownNCT05701410
What this trial is testing

Prevalence of Cardiac Amyloidosis Among Patients With a History of Lumbar Spinal Stenosis.

Who this might be right for
Cardiac AmyloidosisSpinal Stenosis
Steen Hvitfeldt Poulsen 200
Large-scale testing (Phase 3)Study completedNCT05184088
What this trial is testing

Efficacy of [18F]Florbetaben PET for Diagnosis of Cardiac AL Amyloidosis

Who this might be right for
Cardiac AmyloidosisAL AmyloidosisATTR Amyloidosis
Lantheus Germany GmbH 244
Not applicableLooking for participantsNCT04561518
What this trial is testing

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

Who this might be right for
Transthyretin-Mediated AmyloidosisATTR Amyloidosis
Alnylam Pharmaceuticals 1,500
Large-scale testing (Phase 3)Study completedNCT02791230
What this trial is testing

Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
Pfizer 1,733
Not applicableEnded earlyNCT03328338
What this trial is testing

Mitochondrial Function in Transthyretin Amyloidosis

Who this might be right for
Cardiac Amyloidosis
University Hospital Center of Martinique 12
Not applicableActive Not RecruitingNCT05103943
What this trial is testing

Amyloidosis TTR Flow Reserve Evaluation

Who this might be right for
Amyloid Cardiomyopathy
Centre Hospitalier Régional d'Orléans 50
Not applicableLooking for participantsNCT07232459
What this trial is testing

[18F]FT8 PET Imaging in Immunoglobulin Light Chain Amyloidosis

Who this might be right for
AmyloidCardiac AmyloidosisAmyloidosis+1 more
Tianjin Medical University 25
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