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Results for “Amyloidosis, Hereditary, Transthyretin-Related”

133 trials

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Showing 20 of 133 results

Not applicableLooking for participantsNCT07196839
What this trial is testing

Determining the Association of TTR Stabilizing Therapy With Circulating TTR Amyloid Aggregates Over Time in Patients With ATTR-CM: Longitudinal Biomarker Study

Who this might be right for
Transthyretin (TTR) Amyloid Cardiomyopathy
University of Texas Southwestern Medical Center 50
Not applicableLooking for participantsNCT04850105
What this trial is testing

A Non-interventional Cohort Safety Study of Patients With hATTR-PN

Who this might be right for
Hereditary Transthyretin Amyloidosis With Polyneuropthy
Akcea Therapeutics 240
Not applicableLooking for participantsNCT07644325
What this trial is testing

Concordance for Transthyretin Amyloidosis Between Synovial Biopsy and Anterior Carpal Ligament Biopsy

Who this might be right for
Carpal TunnelTransthyretin Amyloidosis
Clinique Saint Jean, France 500
Not applicableLooking for participantsNCT05697861
What this trial is testing

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid PolyneuropathyTransthyretin-Related (ATTR) Familial Amyloid CardiomyopathyWild-Type Transthyretin Cardiac Amyloidosis
Intellia Therapeutics 72
Not applicableUnknownNCT05196594
What this trial is testing

Analysis of the Instestinal Microbiome of Patients With Transthyretin Amyloidosis

Who this might be right for
Amyloidosis, Hereditary, Transthyretin-RelatedMicrobial Colonization
University of Sao Paulo General Hospital 60
Testing effectiveness (Phase 2)Study completedNCT01171859
What this trial is testing

Safety, Efficacy and Pharmacokinetics of Doxycycline Plus Tauroursodeoxycholic Acid in Transthyretin Amyloidosis

Who this might be right for
Transthyretin Amyloidosis
Fondazione IRCCS Policlinico San Matteo di Pavia 40
Not applicableLooking for participantsNCT04561518
What this trial is testing

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

Who this might be right for
Transthyretin-Mediated AmyloidosisATTR Amyloidosis
Alnylam Pharmaceuticals 1,500
Testing effectiveness (Phase 2)Ended earlyNCT03702829
What this trial is testing

24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy Patients

Who this might be right for
Amyloidosis
Brigham and Women's Hospital 31
Not applicableEnded earlyNCT03328338
What this trial is testing

Mitochondrial Function in Transthyretin Amyloidosis

Who this might be right for
Cardiac Amyloidosis
University Hospital Center of Martinique 12
Not applicableStudy completedNCT05075798
What this trial is testing

Study of Cerebral MRI Anomalies in Mutated Transthyretin Amyloidosis Patients

Who this might be right for
Transthyretin Amyloidosis
Centre Hospitalier Universitaire de Nīmes 36
Not applicableStudy completedNCT03842163
What this trial is testing

Prevalence and Characteristics of Transthyretin Amyloidosis in Patients With Left Ventricular Hypertrophy of Unknown Etiology

Who this might be right for
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)
Pfizer 812
Large-scale testing (Phase 3)Study completedNCT02175004
What this trial is testing

Extension Study Assessing Long Term Safety and Efficacy of IONIS-TTR Rx in Familial Amyloid Polyneuropathy (FAP)

Who this might be right for
FAPFamilial Amyloid PolyneuropathyTTR+2 more
Ionis Pharmaceuticals, Inc. 135
Not applicableStudy completedNCT01432587
What this trial is testing

The Effect of Diflunisal on Familial Transthyretin Amyloidosis

Who this might be right for
Amyloidosis
Umeå University 55
Not applicableUnknownNCT04986826
What this trial is testing

Exercise Effect on Transthyretin Stability

Who this might be right for
Amyloidosis TransthyretinAthlete Heart
Oregon Health and Science University 24
Large-scale testing (Phase 3)Looking for participantsNCT06563895
What this trial is testing

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

Who this might be right for
AmyloidosisAmyloid CardiomyopathyTransthyretin Amyloidosis+3 more
Eidos Therapeutics, a BridgeBio company 587
Not applicableLooking for participantsNCT05489549
What this trial is testing

Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

Who this might be right for
Amyloidosis, HereditaryAmyloidosis CardiacAmyloidosis, Familial+2 more
University of Texas Southwestern Medical Center 500
Early research (Phase 1)Study completedNCT05374564
What this trial is testing

Parametric Cardiac 18F-flutemetamol PET Imaging in ATTR Cardiomyopathy

Who this might be right for
Cardiomyopathies, Primary
Yale University 12
Not applicableStudy completedNCT03431896
What this trial is testing

Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis

Who this might be right for
AmyloidosisAmyloidAmyloid Neuropathies, Familial+4 more
The Cleveland Clinic 37
Very early researchStudy completedNCT05023889
What this trial is testing

Spectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran Therapy

Who this might be right for
PolyneuropathiesWild Type ATTR AmyloidosisWild-Type Transthyretin-Related (ATTR)Amyloidosis+2 more
Austin Neuromuscular Center 10
Not applicableLooking for participantsNCT06845644
What this trial is testing

Longitudinal Quantitative Neuromuscular MRI in Neuropathic Patients

Who this might be right for
Charcot-Marie-Tooth Neuropathy Type 1AHereditary Transthyretin Amyloid NeuropathyAcquired Demyelinating Neuropathy
Assistance Publique Hopitaux De Marseille 120
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