Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Anal High Grade Squamous Intraepithelial Lesion”

39 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 39 results

Not applicableStudy completedNCT02007421
What this trial is testing

Study of the Prevention of Anal Cancer

Who this might be right for
Human PapillomavirusCancer
Kirby Institute 617
Testing effectiveness (Phase 2)UnknownNCT03113942
What this trial is testing

Study of Pomalidomide in Anal Cancer Precursors

Who this might be right for
High Grade Squamous Intra-epithelial Lesion (HSIL)
Kirby Institute 26
Early research (Phase 1)Looking for participantsNCT06626230
What this trial is testing

Safety of Anal Curcumin

Who this might be right for
Anal High Grade Squamous Intraepithelial Lesion
Lisa Flowers 48
Testing effectiveness (Phase 2)Study completedNCT03499795
What this trial is testing

VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2

Who this might be right for
Anal Neoplasm
Inovio Pharmaceuticals 23
Not applicableStudy completedNCT02836522
What this trial is testing

Validation of a Health-Related Symptom Index for Persons Diagnosed With and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions (HSIL)

Who this might be right for
Anal High-Grade Squamous Intraepithelial Lesions
Memorial Sloan Kettering Cancer Center 406
Not applicableStudy completedNCT01970787
What this trial is testing

A Trial of Radiofrequency Ablation for Anal Intraepithelial Neoplasia Using the HALO Ablation System

Who this might be right for
HIV-negative Subjects With Intra-anal Intraepithelial Neoplasia Containing High-Grade Squamous Intraepithelial Lesions
Medtronic - MITG 22
Not applicableLooking for participantsNCT07029152
What this trial is testing

Screening for Anal Cancer in Men Who Have Sex With Men Using Pre-Exposure Prophylaxis

Who this might be right for
Anal CancerSquamous Intraepithelial LesionsHSIL, High Grade Squamous Intraepithelial Lesions+3 more
Universitair Ziekenhuis Brussel 296
Not applicableUnknownNCT05858021
What this trial is testing

COrSIcA: Disease Measurement

Who this might be right for
Anal Intraepithelial NeoplasiaAnal High-grade Squamous Intraepithelial LesionAnal HSIL
David Finch 30
Testing effectiveness (Phase 2)Study completedNCT00550589
What this trial is testing

Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the Anus

Who this might be right for
Anal CancerPrecancerous Condition
AIDS Malignancy Consortium 33
Testing effectiveness (Phase 2)Study completedNCT02858310
What this trial is testing

E7 TCR T Cells for Human Papillomavirus-Associated Cancers

Who this might be right for
Papillomavirus InfectionsCervical Intraepithelial NeoplasiaCarcinoma In Situ+2 more
National Cancer Institute (NCI) 219
Not applicableStudy completedNCT02189161
What this trial is testing

A Safety and Tolerability of Circumferential Anal Canal Radiofrequency Ablation For Anal Intraepithelial Neoplasia

Who this might be right for
Anal Intraepithelial Neoplasia (AIN)High-grade Squamous Intraepithelial Lesions (HSIL)
Medtronic - MITG 10
Large-scale testing (Phase 3)Study completedNCT01164722
What this trial is testing

Infrared Coagulator Ablation or Observation in Preventing Anal Cancer in HIV-Positive Patients With Anal Neoplasia

Who this might be right for
Anal CancerNeoplasm of Uncertain Malignant PotentialNonneoplastic Condition+1 more
AIDS Malignancy Consortium 120
Testing effectiveness (Phase 2)Study completedNCT04563754
What this trial is testing

The Effectiveness of High Resolution Microendoscopy for People Living With HIV

Who this might be right for
Anal High Grade Squamous Intraepithelial Lesion
Baylor College of Medicine 163
Testing effectiveness (Phase 2)Study completedNCT03603808
What this trial is testing

VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions

Who this might be right for
Anal Intraepithelial NeoplasiaHigh Grade Squamous Intraepithelial NeoplasiaHIV Positivity+2 more
AIDS Malignancy Consortium 35
Not applicableEnded earlyNCT02503111
What this trial is testing

The HPV-SAVE Study Team: HPV Screening and Vaccine Evaluation in Men Who Have Sex With Men

Who this might be right for
Anal DysplasiaHuman PapillomavirusAnal Cancer
University Health Network, Toronto 71
Testing effectiveness (Phase 2)Study completedNCT00622440
What this trial is testing

Treatment of Anal High-grade Squamous Intraepithelial Lesions (HSIL) Through Use of a Chinese Herbal Topical Cream

Who this might be right for
Anus Neoplasms
University of California, San Francisco 70
Testing effectiveness (Phase 2)UnknownNCT03302858
What this trial is testing

A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand

Who this might be right for
HSIL, High Grade Squamous Intraepithelial LesionsAnal CancerHPV-Related Squamous Cell Carcinoma+3 more
Stephen E. Goldstone 70
Large-scale testing (Phase 3)Study completedNCT02059499
What this trial is testing

Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions

Who this might be right for
Anal Intraepithelial NeoplasiaHigh-grade Squamous Intraepithelial LesionHIV Infection
AIDS Malignancy Consortium 91
Early research (Phase 1)Not Yet RecruitingNCT06233331
What this trial is testing

Use of ACU-D1 in HPV Associated Vulvar and Perianal Lesions in People With HIV

Who this might be right for
Human Papilloma VirusHuman Immunodeficiency VirusAnal Intraepithelial Neoplasia+1 more
Emory University 9
Not applicableEnded earlyNCT02140021
What this trial is testing

Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer

Who this might be right for
Cervical AdenocarcinomaCervical Adenocarcinoma In SituCervical Intraepithelial Neoplasia+52 more
M.D. Anderson Cancer Center 409
Load More Results