Large-scale testing (Phase 3)Enrolling By InvitationNCT06415344What this trial is testingLong-term Extension of GTX-102 in Angelman SyndromeWho this might be right forAngelman Syndrome Ultragenyx Pharmaceutical Inc 255
Early research (Phase 1)Study completedNCT00829439What this trial is testingStudy on Tolerability of Levodopa/Carbidopa in Children With Angelman SyndromeWho this might be right forAngelman Syndrome Boston Children's Hospital 16
Not applicableStudy completedNCT00773825What this trial is testingGenomic Imprinting and Assisted Reproductive TechnologiesWho this might be right forNatural PregnancyPregnancy, Ovarian Assistance Publique - Hôpitaux de Paris 542
Testing effectiveness (Phase 2)Looking for participantsNCT05127226What this trial is testingHALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman SyndromeWho this might be right forAngelman Syndrome Ionis Pharmaceuticals, Inc. 70
Not applicableLooking for participantsNCT06353620What this trial is testingStructural-functional Connectome in Drug-resistant Epilepsies and Neurodevelopmental Syndromes With EpilepsyWho this might be right forEpilepsyAngelman SyndromeDup15q Syndrome IRCCS Eugenio Medea 120
Not applicableLooking for participantsNCT05293184What this trial is testingThe Global Angelman Syndrome RegistryWho this might be right forAngelman Syndrome Foundation for Angelman Syndrome Therapeutics, Australia 5,000
Not applicableAvailableNCT07136454What this trial is testingExpanded Access/Compassionate Use of Rugonersen in Patients With Angelman SyndromeWho this might be right forAngelman Syndrome Oak Hill Bio Ltd
Large-scale testing (Phase 3)Study completedNCT01906866What this trial is testingEfficacy and Safety of Circadin® in the Treatment of Sleep Disturbances in Children With Neurodevelopment DisabilitiesWho this might be right forSleep Disorders Neurim Pharmaceuticals Ltd. 125
Not applicableLooking for participantsNCT06737718What this trial is testingUse of Eye Tracking to Study Social Perception Abnormalities in Children With Angelman SyndromeWho this might be right forAngelman Syndrome Assistance Publique - Hôpitaux de Paris 60
Testing effectiveness (Phase 2)Study completedNCT05630066What this trial is testingInvestigate the Pharmacokinetics (PK) and Safety and to Provide Proof of Mechanism of Alogabat in Children and Adolescents Aged 5-17 Years With Angelman Syndrome (AS) With Deletion Genotype.Who this might be right forAngelman Syndrome Hoffmann-La Roche 48
Not applicableLooking for participantsNCT04507997What this trial is testingAngelman Syndrome Natural History StudyWho this might be right forAngelman Syndrome Boston Children's Hospital 300
Not applicableStudy completedNCT01531582What this trial is testingMinocycline in the Treatment of Angelman SyndromeWho this might be right forAngelman Syndrome University of South Florida 25
Not applicableStudy completedNCT02381457What this trial is testingSNP-based Microdeletion and Aneuploidy RegisTry (SMART)Who this might be right for22q11 Deletion SyndromeDiGeorge SyndromeTrisomy 21+8 more Natera, Inc. 20,960
Testing effectiveness (Phase 2)WithdrawnNCT02226458What this trial is testingAn Exploratory Open Label Study of EPI-743 (Vincerinone TM) in Children With Autism Spectrum DisorderWho this might be right forAutism Spectrum Disorder Edison Pharmaceuticals Inc
Early research (Phase 1)Study completedNCT01903681What this trial is testingAssessment of the Pharmacokinetics of Circadin® in Children With Neurodevelopmental Disorders and Sleep DisturbancesWho this might be right forSleep Problems Neurim Pharmaceuticals Ltd. 16
Not applicableUnknownNCT05100810What this trial is testingAngelman Syndrome Natural History Study-FAST UKWho this might be right forAngelman Syndrome University of Oxford 40
Not applicableStudy completedNCT05783791What this trial is testingDevelopment of a Newborn Screening Assay for Angelman Syndrome and Prader-Willi SyndromeWho this might be right forAngelman SyndromePrader-Willi Syndrome University of Wisconsin, Madison 11
Not applicableUnknownNCT04768803What this trial is testingGhrelin in Patients With a Rare Disease Associated With Intellectual Disability, and Hyperphagia, and/or Overweight, and/or ObesityWho this might be right forAngelman SyndromeSmith-Magenis SyndromeX Fragile Syndrome+2 more University Hospital, Toulouse 300
Early research (Phase 1)Study completedNCT04863794What this trial is testingAssess Distribution Of RO7248824 In The Central Nervous System Following Single Intrathecal Doses Of [89zr] Labeled RO7248824 In Healthy Male ParticipantsWho this might be right forAngelman Syndrome Hoffmann-La Roche 21
Large-scale testing (Phase 3)Ended earlyNCT03882918What this trial is testingAn Open-Label Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of OV101 in Individuals With Angelman SyndromeWho this might be right forAngelman Syndrome Healx AI 141