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Results for “Antibodies, Donor-Specific”

69 trials

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Showing 20 of 69 results

Post-approval studies (Phase 4)Active Not RecruitingNCT07274462
What this trial is testing

DARA-MVI Study (Daratumumab for Microvascular Inflammation in Kidney Transplantation)

Who this might be right for
Microvascular Inflammation - MVI in Kindey Transplant Recipients
University Hospital, Martin 20
Not applicableStudy completedNCT04888286
What this trial is testing

DSAs in Patients Undergoing Allo-HSCT From Mismatched Donors

Who this might be right for
Hematologic DiseasesStem Cell Transplant Complications
Gruppo Italiano Trapianto di Midollo Osseo 912
Large-scale testing (Phase 3)Study completedNCT04302805
What this trial is testing

RATG Versus rATG Combined With Intravenous Immunoglobulin (IVIG) Induction Immunosuppression in HLA Incompatible Transplantation (INHIBIT)

Who this might be right for
Kidney Transplantation
Institute for Clinical and Experimental Medicine 17
Not applicableNot Yet RecruitingNCT05459181
What this trial is testing

HeartCare Immuno-optimization in Cardiac Allografts (MOSAIC)

Who this might be right for
Heart TransplantImmunosuppressionAllograft
CareDx 930
Large-scale testing (Phase 3)Study completedNCT02374736
What this trial is testing

Effect of Privigen Against Graft Loss

Who this might be right for
Kidney Transplantation
Assistance Publique - Hôpitaux de Paris 18
Large-scale testing (Phase 3)Looking for participantsNCT04877288
What this trial is testing

Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

Who this might be right for
Renal Allograft Recipients
Bristol-Myers Squibb 102
Not applicableUnknownNCT03815864
What this trial is testing

Antibodies and Liver Retransplantation

Who this might be right for
Liver Transplant FailureAntibody-mediated Rejection
London Health Sciences Centre 200
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07451236
What this trial is testing

CD19-BCMA Dual Nanobody Based CAR-T Cells for Patients With DSA

Who this might be right for
Transplantation Candidates With Hematological Diseases
Chang Yingjun 18
Not applicableUnknownNCT03702257
What this trial is testing

DSA Intragraft in Lung Transplantation: Diagnostic and Prognostic Value in Antibody Mediated Rejection

Who this might be right for
Lung Transplant RecipientDonor Specific AntibodiesAntibody Mediated Rejection
University Hospital, Strasbourg, France 80
Early research (Phase 1)Not Yet RecruitingNCT06948097
What this trial is testing

Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific Antibodies

Who this might be right for
Lung Transplantation
National Heart, Lung, and Blood Institute (NHLBI) 30
Not applicableLooking for participantsNCT06025240
What this trial is testing

Expanding the Scope of Post-transplant HLA-specific Antibody Detection and Monitoring in Renal Transplant Recipients

Who this might be right for
Kidney TransplantRenal Transplant FailureKidney Transplant Rejection+5 more
Liverpool University Hospitals NHS Foundation Trust 282
Very early researchEnded earlyNCT03380936
What this trial is testing

Pilot Study of Treatment for Subclinical AMR (Antibody-mediated Rejection) in Kidney Transplant Recipients

Who this might be right for
Kidney Transplant Rejection
University of Colorado, Denver 4
Not applicableUnknownNCT06177561
What this trial is testing

Safety and Efficacy of LPE in Clearing DSA in Patients Who Received Allo-HSCT

Who this might be right for
Leukemia
Ruijin Hospital 38
Not applicableUnknownNCT02556879
What this trial is testing

Immunization Anti HLA in the Liver Transplant Recipients (DSATH)

Who this might be right for
Liver TransplantationGraft Failure
Assistance Publique - Hôpitaux de Paris 100
Early research (Phase 1)Looking for participantsNCT06990711
What this trial is testing

Clinical Trial of Siltuximab for the Treatment of Antibody-Mediated Rejection After Lung Transplantation

Who this might be right for
Antibody Mediated Rejection of Lung Transplant
Washington University School of Medicine 30
Very early researchLooking for participantsNCT06398457
What this trial is testing

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Who this might be right for
Hematologic MalignancyBone Marrow Transplant RejectionAcute Myeloid Leukemia (AML)+9 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 8
Post-approval studies (Phase 4)Active Not RecruitingNCT04665310
What this trial is testing

Evaluation of Anti-rejection Drug, Tacrolimus, in African-Americans With Kidney Transplant

Who this might be right for
Kidney Disease, End-StageDonor Specific AntibodiesAcute Rejection of Renal Transplant
The Methodist Hospital Research Institute 46
Not applicableActive Not RecruitingNCT02784080
What this trial is testing

Donor Specific HLA Alloantibodies in Liver Transplantation

Who this might be right for
Complication of Transplanted Liver
Rigshospitalet, Denmark 858
Testing effectiveness (Phase 2)Study completedNCT03388008
What this trial is testing

Belatacept Pilot Study in Lung Transplantation Immunosuppression in Lung Transplantation

Who this might be right for
Lung Transplant RejectionAntibody-mediated Rejection
Washington University School of Medicine 27
Not applicableStudy completedNCT03238443
What this trial is testing

Interest of the Donor-specific Antibodies After Liver Transplantation

Who this might be right for
Liver Transplant
University Hospital, Lille 120
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