Post-approval studies (Phase 4)Study completedNCT01343381What this trial is testingComparison of Heparin Types; Efficacy and SafetyWho this might be right forCoronary Artery Disease McMaster University 21
Not applicableStudy completedNCT01795781What this trial is testingAssays for and Reversal of New AnticoagulantsWho this might be right forAtrial FibrillationOsteoarthritis of the KneeOsteoarthritis of the Hip R.P.Herrmann 30
Large-scale testing (Phase 3)Study completedNCT00618098What this trial is testingStudy of Octaplex (Human Prothrombin Complex Concentrate) and Fresh Frozen Plasma in Patients Under Vitamin K Therapy Antagonist Needing Urgent Surgery or Invasive ProceduresWho this might be right forReversal of Anticoagulant Treatment Octapharma 200
Large-scale testing (Phase 3)Study completedNCT00708435What this trial is testingEfficacy and Safety Study of BERIPLEX® P/N (Kcentra) Compared With Plasma in Patients With Acute Major Bleeding Caused by Anticoagulant TherapyWho this might be right forBlood Coagulation DisordersAcute Major Bleeding CSL Behring 216
Not applicableUnknownNCT02745054What this trial is testingSafety of Oral Anticoagulants RegistryWho this might be right forBlood Coagulation Hospital Quality Foundation 1,500
Large-scale testing (Phase 3)Study completedNCT02207725What this trial is testingA Study in Older Subjects to Evaluate the Safety and Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of ApixabanWho this might be right forBleeding Portola Pharmaceuticals 68
Large-scale testing (Phase 3)Study completedNCT02220725What this trial is testingA Study in Older Subject to Evaluate the Safety and Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of RivaroxabanWho this might be right forBleeding Portola Pharmaceuticals 80
Large-scale testing (Phase 3)Looking for participantsNCT05156983What this trial is testingTAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent SurgeryWho this might be right forCoagulation Disorder Takeda 328
Not applicableStudy completedNCT04614090What this trial is testingFast Reversal of Warfarin and Early Surgery in Patients With Trochanteric Hip Fracture A Case-control StudyWho this might be right forTrochanteric Hip FracturesWarfarin MedicationEarly Surgery Karolinska Institutet 198
Post-approval studies (Phase 4)Study completedNCT03064035What this trial is testingFixed Versus Variable Dosing of 4-factor Prothrombin Complex Concentrate for Emergent Warfarin ReversalWho this might be right forAcute Bleeding on Long-Term Anticoagulation TherapyHemorrhageSignificant Bleeding in Patients With a Coagulopathy (Prolonged Thrombin Time)+1 more HealthPartners Institute 79
Not applicableLooking for participantsNCT06429787What this trial is testingPost Marketing Observational Study on Safety of BALFAXAR vs. KCENTRA for Reversal of Vitamin K Antagonist Induced Anticoagulation in Adults Undergoing Urgent Surgery or Invasive ProcedureWho this might be right forVitamin K-Dependent Coagulation DefectSignificant Bleeding Risk Octapharma 3,574
Early research (Phase 1)Study completedNCT01826266What this trial is testingEffects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of EdoxabanWho this might be right forAnticoagulant ReversalReversal of Edoxaban Induced Anticoagulation Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc. 83
Post-approval studies (Phase 4)UnknownNCT03473132What this trial is testingAssessment of Coagulation Factor Levels in Left Ventricular Device (LVAD )Patients Following Temporary Warfarin Reversal With Four Factor Prothrombin Complex Concentrate (4F-PCC)Who this might be right forAnticoagulationAnticoagulation Reversal Brigham and Women's Hospital 50
Large-scale testing (Phase 3)Study completedNCT02740335What this trial is testingStudy of Octaplex, a Four-factor Prothrombin Complex Concentrate (4F-PCC) and Beriplex® P/N (Kcentra) for the Reversal of Vitamin K Antagonist (VKA) Induced Anticoagulation in Patients Needing Urgent Surgery With Significant Bleeding Risk.Who this might be right forSignificant Bleeding Risk Octapharma 208
Post-approval studies (Phase 4)Study completedNCT03140631What this trial is testingUse of Protamine for Heparin Reversal After Catheter Ablation of Atrial FibrillationWho this might be right forAtrial FibrillationCatheter Ablation University of Michigan 153
Large-scale testing (Phase 3)Study completedNCT02329327What this trial is testingA Study in Participants With Acute Major Bleeding to Evaluate the Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Direct and Indirect Oral Anticoagulants (Extension Study)Who this might be right forBleeding Alexion Pharmaceuticals, Inc. 479
Large-scale testing (Phase 3)Study completedNCT00168077What this trial is testingProthrombin Complex Concentrate for Anticoagulant ReversalWho this might be right forAcquired Coagulation Factor Deficiency CSL Behring 40
Testing effectiveness (Phase 2)Study completedNCT02206100What this trial is testingPK and PD of Single, Escalating Doses of PER977 Following EnoxaparinWho this might be right forHealthy Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc. 40
Testing effectiveness (Phase 2)Study completedNCT02206087What this trial is testingEvaluation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of PER977 Following HeparinWho this might be right forHealthy Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc. 60
Testing effectiveness (Phase 2)WithdrawnNCT04794348What this trial is testingClinical Trial Assessing Non-Inferiority of Freeze Dried Plasma to Fresh Frozen Plasma in Reversing WarfarinWho this might be right forAnticoagulant Reversal Teleflex