Post-approval studies (Phase 4)UnknownNCT04521452What this trial is testingRandomized, Open-label Trial of Inhibitory Effect of Evogliptin on Progression of CAVDWho this might be right forCAVD Asan Medical Center 218
Not applicableStudy completedNCT01755806What this trial is testingComparison of Aortic Root Dimension Changes During Cardiac Cycle Between the Patients With and Without Aortic Valve Calcification Using ECG-gated 64-slice and Dual-source 256-slice Computed Tomography Scanners: Results of a Multicenter StudyWho this might be right forAortic Valve Calcification Modarres Hospital 104
Large-scale testing (Phase 3)Study completedNCT00785109What this trial is testingVitamin K Supplement for Inhibition of the Progress in Aortic Valve CalcificationWho this might be right forAortic Valve Calcification RWTH Aachen University 99
Large-scale testing (Phase 3)Ended earlyNCT05143177What this trial is testingEvaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease With Mild to Moderate Aortic Stenosis (EVOID-AS)Who this might be right forCalcific Aortic Valve Disease REDNVIA Co., Ltd. 486
Not applicableUnknownNCT03088787What this trial is testingFeasibility of Continuous Noninvasive Finger Arterial Blood Pressure Measurement for Detection and Staging of Aortic StenosisWho this might be right forAortic Stenosis, Calcific Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 100
Not applicableStudy completedNCT03858413What this trial is testingA-Klotho in Relation to Calcification in the Coronary Arteries and Aortic Valve in Patients With Chronic Kidney DiseaseWho this might be right forVascular CalcificationChronic Kidney Diseases Royal Brompton & Harefield NHS Foundation Trust 60
Early research (Phase 1)Study completedNCT02049203What this trial is testingSafety of Ataciguat in Patients With Moderate Calcific Aortic Valve StenosisWho this might be right forAortic Valve Stenosis Jordan D. Miller, Ph.D. 44
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07715279What this trial is testingVericiguat for the Inhibition of Calcific Aortic Valve Stenosis ProgressionWho this might be right forCalcific Aortic Valve DiseaseAORTIC VALVE DISEASESAortic Valve Stenosis West China Hospital 238
Not applicableStudy completedNCT03343314What this trial is testingEffective Management of Calcific Aortic Stenosis in the ElderlyWho this might be right forCalcific Aortic Stenosis French Cardiology Society 1,101
Not applicableStudy completedNCT04359030What this trial is testingFreestyle-Perimount Calcification ComparisonWho this might be right forAortic Valve DiseaseValve Heart Disease Ziekenhuis Oost-Limburg 90
Not applicableStudy completedNCT06079008What this trial is testingThe Association of Cardiac Valve Calcification and 1-year Mortality After Lower-extremity Amputation in Diabetic PatientsWho this might be right forAmputationDiabetic FootValve Disease, Aortic+1 more Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 96
Not applicableStudy completedNCT02193035What this trial is testingMicroparticles in Severe Aortic StenosisWho this might be right forAortic Valve Stenosis InCor Heart Institute 15
Not applicableStudy completedNCT02935491What this trial is testing4 Cities for Assessing CAlcification PRognostic Impact After TAVIWho this might be right forHeart Disease Hospices Civils de Lyon 1,600
Not applicableStudy completedNCT02255851What this trial is testingSentinel(TM) Post-Market RegistryWho this might be right forTranscatheter Aortic Valve ReplacementSevere Symptomatic Calcified Native Aortic Valve Stenosis Claret Medical 300
Very early researchNot Yet RecruitingNCT06996223What this trial is testingA Multicenter, Prospective, Randomized Controlled Trial to Evaluate the Efficacy of PCSK-9 Inhibitors in Delaying the Progression of Calcified Aortic Valve DiseaseWho this might be right forAortic StenosisPCSK9 InhibitorCalcified Aortic Valve Disease Nanfang Hospital, Southern Medical University 316
Not applicableLooking for participantsNCT06688448What this trial is testingValvular Assessment of New Generation Aortic Replacement DevicesWho this might be right forAortic Regurgitation DiseaseAortic Valve CalcificationBicuspid Aortic Valve Disease Instituto Dante Pazzanese de Cardiologia 200
Not applicableActive Not RecruitingNCT05182307What this trial is testingDurAVR™ THV System: EMBARK StudyWho this might be right forSymptomatic Aortic StenosisSevere Aortic Valve StenosisAortic Valve Calcification Anteris Technologies Ltd. 150
Not applicableActive Not RecruitingNCT05712161What this trial is testingUse of DurAVR™ THV System in Subjects With Severe Aortic Stenosis: Early Feasibility StudyWho this might be right forAortic StenosisSymptomatic Aortic StenosisSevere Aortic Valve Stenosis+1 more Anteris Technologies Ltd. 15
Not applicableStudy completedNCT02184442What this trial is testingThe PARTNER II Trial: Placement of AoRTic TraNscathetER Valves - PII BWho this might be right forSevereSymptomaticCalcific Aortic Stenosis Edwards Lifesciences 560
Not applicableActive Not RecruitingNCT03613246What this trial is testingNVT ALLEGRA TAVI System TF in Failing Calcified Aortic Heart Valves in a Real-world Patient PopulationWho this might be right forTranscatheter Aortic Valve Implantation NVT GmbH 346