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Results for “Apoptosis Regulatory Proteins”

68 trials

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Showing 20 of 68 results

Testing effectiveness (Phase 2)UnknownNCT04014101
What this trial is testing

SHR-1210 Plus Apatinib in Patients With Advanced-Stage Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Shanghai Zhongshan Hospital 40
Testing effectiveness (Phase 2)WithdrawnNCT03167177
What this trial is testing

QUILT-3.046: NANT Melanoma Vaccine: Combination Immunotherapy in Subjects With Melanoma Who Have Progressed On or After Chemotherapy and PD-1/PD-L1 Therapy

Who this might be right for
Melanoma
ImmunityBio, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT07209189
What this trial is testing

Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

Who this might be right for
Head and Neck CancerSquamous Cell CarcinomaOral Cavity Cancer+6 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 75
Very early researchActive Not RecruitingNCT04134325
What this trial is testing

Study of PD-1 Inhibitors After CD30.CAR T Cell Therapy in Relapsed/Refractory Hodgkin Lymphoma

Who this might be right for
Relapsed Hodgkin LymphomaRefractory Hodgkin Lymphoma
UNC Lineberger Comprehensive Cancer Center 10
Early research (Phase 1)Not Yet RecruitingNCT07481175
What this trial is testing

Inhibiting the Anti-apoptotic Factor, BCL-2, at the Time of ART Initiation to Promote Apoptosis of HIV-infected Cells and Restrict the Seeding of the HIV Reservoir: An Investigator-initiated Randomised, Controlled, Open-label Clinical Trial (The INITIATE Study)

Who this might be right for
HIV-1
Thomas Aagaard Rasmussen 38
Testing effectiveness (Phase 2)UnknownNCT04926532
What this trial is testing

Toripalimab Plus Sorafenib in Patients With Advanced-Stage Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Shanghai Zhongshan Hospital 30
Testing effectiveness (Phase 2)Study completedNCT02968940
What this trial is testing

Avelumab With Hypofractionated Radiation Therapy in Adults With Isocitrate Dehydrogenase (IDH) Mutant Glioblastoma

Who this might be right for
Glioblastoma
NYU Langone Health 6
Not applicableUnknownNCT04922541
What this trial is testing

Multi-center Observational Study on the Progression of Atherosclerotic Plaques in Anti-PD-1 mAb Treated Tumor Patients by Artery Ultrasound Follow-up

Who this might be right for
Plaque, AtheroscleroticProgrammed Cell Death Protein 1 Inhibitor
Second Affiliated Hospital, School of Medicine, Zhejiang University 50
Testing effectiveness (Phase 2)Looking for participantsNCT05668026
What this trial is testing

Administration of Venetoclax to Promote Apoptosis of HIV-infected Cells and Reduce the Size of the HIV Reservoir Among People Living With HIV on ART

Who this might be right for
HIV-1-infection
University of Aarhus 18
Early research (Phase 1)Not Yet RecruitingNCT07476326
What this trial is testing

Pharmacokinetics, Safety, and Immunogenicity Comparison of Bmab1700 and Opdivo® as Adjuvant Monotherapy in Participants With Melanoma

Who this might be right for
Melanoma
Biocon Biologics UK PLC 120
Early research (Phase 1)Looking for participantsNCT05142189
What this trial is testing

Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung Cancer
BioNTech SE 320
Testing effectiveness (Phase 2)Study completedNCT03317327
What this trial is testing

REirradiation and Programmed Cell Death Protein 1 (PD-1) Blockade On Recurrent Squamous Cell Head and Neck Tumors

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Oslo University Hospital 20
Early research (Phase 1)Looking for participantsNCT07391670
What this trial is testing

A Phase I Dose Escalation and Dose Expansion Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Durvalumab

Who this might be right for
Solid Tumours
AstraZeneca 40
Testing effectiveness (Phase 2)Looking for participantsNCT03753243
What this trial is testing

Neoadjuvant Pembrolizumab Plus Androgen Axis Blockade Prior to Prostatectomy for High Risk Localized Prostate Cancer

Who this might be right for
Prostate Cancer
Mark Garzotto, MD 32
Not applicableStudy completedNCT06865976
What this trial is testing

Genomic and Proteomic Analyses of Apoptosis Mechanisms in Diseased Peri-implant Tissue

Who this might be right for
ApoptosisApoptosis Regulatory ProteinsProteases+1 more
Sakarya University 72
Large-scale testing (Phase 3)Study completedNCT02603432
What this trial is testing

Avelumab In Patients With Locally Advanced Or Metastatic Urothelial Cancer (JAVELIN Bladder 100)

Who this might be right for
Urothelial Cancer
Pfizer 700
Testing effectiveness (Phase 2)Looking for participantsNCT06529523
What this trial is testing

Tislelizumab in People With Colorectal Cancer

Who this might be right for
Colorectal Cancer
Memorial Sloan Kettering Cancer Center 40
Not applicableLooking for participantsNCT05328024
What this trial is testing

Identification of Predictive Factors for the Response to Anti-Programmed Cell Death Protein 1 (PD1) Immunotherapy in Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Cancer
Institut de cancérologie Strasbourg Europe 60
Testing effectiveness (Phase 2)Study completedNCT04361331
What this trial is testing

Two-cohort Study of Toripalimab(PD1)+Lenvatnib, or Gemox+Lenvatinib in Advanced Intrahepatic Cholangiocarcinoma

Who this might be right for
Cholangiocarcinoma, Intrahepatic
Shanghai Zhongshan Hospital 61
Testing effectiveness (Phase 2)WithdrawnNCT03169738
What this trial is testing

QUILT-3.044: NANT Non-small Cell Lung Cancer (NSCLC) Vaccine: Combination Immunotherapy in Subjects With NSCLC Who Have Progressed After Treatment With PD-1/PD-L1 Inhibitors

Who this might be right for
Non-small Cell Lung Cancer
ImmunityBio, Inc.
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