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Results for “Autosomal”

798 trials

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Showing 20 of 798 results

Post-approval studies (Phase 4)Study completedNCT04489888
What this trial is testing

Pembrolizumab (MK-3475) Plus Carboplatin and Paclitaxel as First-line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (MK-3475-B10/KEYNOTE B10)

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
Merck Sharp & Dohme LLC 101
Testing effectiveness (Phase 2)Study completedNCT00841568
What this trial is testing

A Long-term Administration Study of OPC-41061 in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Extension of Study 156-04-001]

Who this might be right for
Autosomal Dominant Polycystic Kidney Disease
Otsuka Pharmaceutical Co., Ltd. 17
Large-scale testing (Phase 3)Study completedNCT02819518
What this trial is testing

Study of Pembrolizumab (MK-3475) Plus Chemotherapy vs. Placebo Plus Chemotherapy for Previously Untreated Locally Recurrent Inoperable or Metastatic Triple Negative Breast Cancer (MK-3475-355/KEYNOTE-355)

Who this might be right for
Triple Negative Breast Cancer (TNBC)
Merck Sharp & Dohme LLC 882
Not applicableStudy completedNCT02572713
What this trial is testing

Systemic Synuclein Sampling Study (S4)

Who this might be right for
Parkinson's Disease
Michael J. Fox Foundation for Parkinson's Research 80
Not applicableStudy completedNCT04363554
What this trial is testing

The Kidneys Ability to Concentrate and Dilute Urine in Patients With Autosomal Dominant Polycystic Kidney Disease

Who this might be right for
Polycystic Kidney, Autosomal DominantChronic Kidney Diseases
Regional Hospital Holstebro 51
Not applicableNot Yet RecruitingNCT07477769
What this trial is testing

Lymphocyte Phenotype of Autosomal Recessive Congenital Ichthyoses Mutated NIPAL4 (Nipal4-nEDD)

Who this might be right for
Sezary SyndromeIchthyosis, Lamellar
Assistance Publique - Hôpitaux de Paris 10
Large-scale testing (Phase 3)Study completedNCT00991146
What this trial is testing

Efficacy and Safety Study of Canakinumab Administered for 6 Months (24 Weeks) in Japanese Patients With Cryopyrin-associated Periodic Syndromes Followed by an Extension Phase

Who this might be right for
Cryopyrin-associated Periodic SyndromesFamilial Cold Autoinflammatory SyndromeMuckle-Wells Syndrome+1 more
Novartis Pharmaceuticals 19
Not applicableLooking for participantsNCT06967831
What this trial is testing

Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells

Who this might be right for
Leigh Syndrome (Maternally Inherited, MILS)Leigh Syndrome (AR, AD, XR)
Charite University, Berlin, Germany 80
Large-scale testing (Phase 3)Study completedNCT04246177
What this trial is testing

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

Who this might be right for
Carcinoma, Hepatocellular
Merck Sharp & Dohme LLC 479
Not applicableLooking for participantsNCT04724941
What this trial is testing

Prodromal Alpha-Synuclein Screening in Parkinson's Disease Study

Who this might be right for
Parkinson Disease
University Hospital Schleswig-Holstein 2,000
Large-scale testing (Phase 3)Study completedNCT01377246
What this trial is testing

Somatostatin In Patients With Autosomal Dominant Polycystic Kidney Disease And Moderate To Severe Renal Insufficiency

Who this might be right for
Autosomal Dominant Polycystic Kidney Disease
Mario Negri Institute for Pharmacological Research 100
Large-scale testing (Phase 3)Study completedNCT04934722
What this trial is testing

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)-China Extension

Who this might be right for
Metastatic Hormone-Sensitive Prostate Cancer
Merck Sharp & Dohme LLC 186
Not applicableLooking for participantsNCT01109368
What this trial is testing

The Rogosin Institute Homozygous Familial Hypercholesterolemia Repository

Who this might be right for
Homozygous Familial Hypercholesterolemia
The Rogosin Institute 60
Testing effectiveness (Phase 2)UnknownNCT01561599
What this trial is testing

Study on Delayed Graft Function Using Paired Kidneys

Who this might be right for
Delayed Graft Function
Angion Biomedica Corp 12
Not applicableActive Not RecruitingNCT05227287
What this trial is testing

ADH1 and ADH2 Disease Monitoring Study (DMS)

Who this might be right for
Autosomal Dominant Hypocalcemia
Calcilytix Therapeutics, Inc., a BridgeBio company 95
Testing effectiveness (Phase 2)Study completedNCT03181399
What this trial is testing

Diet Treatment Glucose Transporter Type 1 Deficiency (G1D)

Who this might be right for
GLUT1DS1EpilepsyGlut1 Deficiency Syndrome 1, Autosomal Recessive+4 more
University of Texas Southwestern Medical Center 45
Not applicableActive Not RecruitingNCT04098211
What this trial is testing

Longitudinal Assessment of Atypical Tripeptidyl Peptidase 1 Enzyme Deficiency Patients

Who this might be right for
Neuronal Ceroid-LipofuscinosesNeuronal Ceroid Lipofuscinosis CLN2Spinocerebellar Ataxia, Autosomal Recessive 7
Children's Hospital of Orange County 5
Not applicableActive Not RecruitingNCT07497412
What this trial is testing

The Effect of Continuous Positive Airway Therapy on the Blood Pressure in Sleepy vs Non-sleepy Patients With Obstructive Sleep Apnea

Who this might be right for
Obstructive Sleep Apnea
King's College London 10,000
Not applicableStudy completedNCT02977923
What this trial is testing

Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: a Pilot Study

Who this might be right for
PainAnxietyBurns+2 more
St. Justine's Hospital 20
Large-scale testing (Phase 3)WithdrawnNCT02053883
What this trial is testing

Cethrin in Acute Cervical Spinal Cord Injury

Who this might be right for
Spinal Cord Injury
BioAxone BioSciences, Inc.
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