Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Autosomal Dominant”

586 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 586 results

Large-scale testing (Phase 3)Study completedNCT01866319
What this trial is testing

Study to Evaluate the Safety and Efficacy of Two Different Dosing Schedules of Pembrolizumab (MK-3475) Compared to Ipilimumab in Participants With Advanced Melanoma (MK-3475-006/KEYNOTE-006)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 834
Large-scale testing (Phase 3)Study completedNCT00426153
What this trial is testing

Octreotide in Severe Polycystic Liver Disease

Who this might be right for
Polycystic Kidney, Autosomal DominantPolycystic Liver DiseaseHepatomegaly+3 more
Mayo Clinic 42
Large-scale testing (Phase 3)Active Not RecruitingNCT05680818
What this trial is testing

Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1

Who this might be right for
Autosomal Dominant Hypocalcemia (ADH)
Calcilytix Therapeutics, Inc., a BridgeBio company 67
Not applicableStudy completedNCT02250287
What this trial is testing

New Quantitive MRI Parameters in Assessing Kidneys of Autosomal Dominant Polycystic Kidney Disease

Who this might be right for
Autosomal Dominant Polycystic Kidney DiseaseKidney Disease
Mayo Clinic 20
Large-scale testing (Phase 3)Study completedNCT04776148
What this trial is testing

Study of Lenvatinib (MK-7902/E7080) in Combination With Pembrolizumab (MK-3475) Versus Standard of Care in Participants With Metastatic Colorectal Cancer (MK-7902-017/E7080-G000-325/LEAP-017)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 563
Not applicableEnded earlyNCT00934791
What this trial is testing

Polycystic Liver Disease in Kidney Transplant

Who this might be right for
Polycystic Liver Disease
Mayo Clinic 2
Testing effectiveness (Phase 2)Study completedNCT03797326
What this trial is testing

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)

Who this might be right for
Advanced Solid TumorsTriple Negative Breast CancerOvarian Cancer+5 more
Merck Sharp & Dohme LLC 611
Not applicableUnknownNCT02843997
What this trial is testing

Endophenotype Characterization of a Family Psychiatric Disorder

Who this might be right for
Healthy Volunteer
University Hospital, Grenoble 29
Testing effectiveness (Phase 2)UnknownNCT01932450
What this trial is testing

Radiofrequency Ablation for ADPKD Blood Pressure and Disease Progression Control

Who this might be right for
Autosomal Dominant Polycystic Kidney DiseaseHypertension
Mei changlin 100
Not applicableStudy completedNCT04407481
What this trial is testing

PErfusioN, OxyGen ConsUmptIon and ENergetics in ADPKD (PENGUIN)

Who this might be right for
Polycystic Kidney Disease, AdultPolycystic Kidney, Autosomal Dominant
University of Colorado, Denver 22
Not applicableLooking for participantsNCT07099651
What this trial is testing

Autosomal Dominant Spinocerebellar Ataxias and Social Cognition

Who this might be right for
Autosomal Dominant Spinocerebellar Ataxia (SCA1, 2,3,6,7,27B)
University Hospital, Angers 160
Large-scale testing (Phase 3)Study completedNCT01905657
What this trial is testing

Study of Two Doses of Pembrolizumab (MK-3475) Versus Docetaxel in Previously Treated Participants With Non-Small Cell Lung Cancer (MK-3475-010/KEYNOTE-010)

Who this might be right for
Non Small Cell Lung Cancer (NSCLC)
Merck Sharp & Dohme LLC 1,034
Not applicableLooking for participantsNCT06941012
What this trial is testing

Validation of α-synuclein Modifications in Parkinson's dIsoRder Evolution

Who this might be right for
Parkinson Disease (PD)
Casa di Cura IGEA 1,200
Large-scale testing (Phase 3)Ended earlyNCT00920309
What this trial is testing

Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD): The Role of Biomarkers in Predicting a Response to Therapy

Who this might be right for
Autosomal Dominant Polycystic Kidney Disease
Yale University 21
Testing effectiveness (Phase 2)Looking for participantsNCT07147348
What this trial is testing

A First-in-human, Dose Escalation and Indication Expansion Study of BNT3212 as Monotherapy or in Combination With BNT327 in Adults With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
BioNTech SE 375
Large-scale testing (Phase 3)Looking for participantsNCT07280585
What this trial is testing

STOP-PKD: SGLT2-inhibition to Improve Prognosis in Polycystic Kidney Disease

Who this might be right for
Polycystic Kidney, Autosomal Dominant
University of Cologne 420
Large-scale testing (Phase 3)Study completedNCT03635567
What this trial is testing

Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic Cervical Cancer (MK-3475-826/KEYNOTE-826)

Who this might be right for
Cervical Cancer
Merck Sharp & Dohme LLC 617
Testing effectiveness (Phase 2)Study completedNCT05190744
What this trial is testing

Probenecid (PB) to Treat Hereditary Nephrogenic Diabetes Insipidus (NDI), ADPKD Treated With Tolvaptan, and Severely Polyuric Patients With Previous Lithium Administration

Who this might be right for
Autosomal Dominant Polycystic Kidney DiseaseNephrogenic Diabetes InsipidusAcquired Nephrogenic Diabetes Insipidus+1 more
Mayo Clinic 36
Early research (Phase 1)Not Yet RecruitingNCT06658964
What this trial is testing

Study to Evaluate the Drug-drug Interaction of JMKX003142 in Healthy Subjects

Who this might be right for
ADPKD (autosomal Dominant Polycystic Kidney Disease)
Jemincare 48
Large-scale testing (Phase 3)Study completedNCT02564263
What this trial is testing

Study of Pembrolizumab (MK-3475) Versus Investigator's Choice Standard Therapy for Participants With Advanced Esophageal/ Esophagogastric Junction Carcinoma That Progressed After First-Line Therapy (MK-3475-181/KEYNOTE-181)

Who this might be right for
Esophageal CarcinomaEsophagogastric Junction Carcinoma
Merck Sharp & Dohme LLC 628
Load More Results