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Results for “B-cell Mediated Autoimmune Disorders”

16 trials

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Showing 16 of 16 results

Not applicableEnded earlyNCT01947036
What this trial is testing

T and B Cell Responses in Autoimmune Diseases

Who this might be right for
Type 1 Diabetes MellitusMultiple SclerosisArthritis, Rheumatoid+2 more
National Institute of Allergy and Infectious Diseases (NIAID) 68
Early research (Phase 1)Looking for participantsNCT06308978
What this trial is testing

FT819 in B-cell Mediated Autoimmune Disease

Who this might be right for
Antineutrophilic Cytoplasmic Antibody (ANCA)- Associated Vasculitis (AAV)Idiopathic Inflammatory Myositis (IIM)Systemic Sclerosis (SSc)+2 more
Fate Therapeutics 244
Very early researchLooking for participantsNCT07629596
What this trial is testing

Evaluation of Safety, Pharmacokinetics and Pharmacodynamics of Arnovie101, an mRNA-LNP-Based In Vivo CAR-T Therapy, for the Treatment of B Cell-Mediated Autoimmune Diseases (SLE and AIHA)

Who this might be right for
Systemic Lupus ErythematosusAutoimmune Hemolytic Anemia (AIHA)
Circunited BioPharma (Shenzhen) Co., Ltd. 5
Not applicableUnknownNCT05245344
What this trial is testing

Effects of Ozanimod on Immune-mediated Mechanisms of Neurodegeneration in Multiple Sclerosis - a Preclinical Study

Who this might be right for
Relapsing-Remitting Multiple Sclerosis (RRMS)Neuromyelitis OpticaHealthy
Neuromed IRCCS 154
Early research (Phase 1)Active Not RecruitingNCT06294236
What this trial is testing

Study Evaluating SC291 in Subjects With Severe r/r B-cell Mediated Autoimmune Diseases (GLEAM)

Who this might be right for
Lupus ErythematosusSystemic Lupus ErythematosusSLE (Systemic Lupus)+3 more
Sana Biotechnology 7
Not applicableNot Yet RecruitingNCT07577583
What this trial is testing

Long-term Follow-up (LTFU) of Participants Who Received Azer-Cel

Who this might be right for
B-cell Mediated Autoimmune Disorders
TG Therapeutics, Inc. 32
Early research (Phase 1)Looking for participantsNCT07085676
What this trial is testing

Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases

Who this might be right for
Systemic Sclerosis (SSc)Idiopathic Inflammatory Myopathy (IIM)Rheumatoid Arthritis (RA)+6 more
Polina Stepensky 120
Testing effectiveness (Phase 2)Looking for participantsNCT06347718
What this trial is testing

CAR-T Cells in Systemic B Cell Mediated Autoimmune Disease

Who this might be right for
Systemic Lupus ErythematosusSystemic SclerosisDermatomyositis+1 more
Miltenyi Biomedicine GmbH 24
Very early researchLooking for participantsNCT07322718
What this trial is testing

Safety and Efficacy Study of RXIM002 in Severe, Relapsed or Refractory Autoimmune Diseases

Who this might be right for
Relapsed/Refractory B Cell-Mediated Autoimmune Diseases
Ruijin Hospital 27
Early research (Phase 1)Active Not RecruitingNCT06255028
What this trial is testing

CNTY-101 in Participants With Refractory B Cell-mediated Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusLupus NephritisIdiopathic Inflammatory Myopathies+1 more
Century Therapeutics, Inc. 6
Early research (Phase 1)Looking for participantsNCT07305116
What this trial is testing

CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B Cell Mediated Autoimmune Disease

Who this might be right for
Autoimmune DiseasesSystemic Lupus Erthematosus (SLE)Multi-Drug Resistant Nephrotic Syndrome+3 more
The Children's Hospital of Zhejiang University School of Medicine 15
Early research (Phase 1)Looking for participantsNCT06249438
What this trial is testing

C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy

Who this might be right for
Systemic Lupus Erythematosus (SLE)Immune-mediated Necrotizing Myopathy (IMNM)Neuromyelitis Optica Spectrum Disorders (NMOSD)+3 more
RenJi Hospital 30
Very early researchLooking for participantsNCT06792799
What this trial is testing

Anti-CD19/BCMA CAR-NK Cells in Patients With B Cell Mediated Autoimmune Disease

Who this might be right for
Autoimmune DiseasesSystemic Lupus ErthematosusMulti-Drug Resistant Nephrotic Syndrome+1 more
The Children's Hospital of Zhejiang University School of Medicine 36
Testing effectiveness (Phase 2)Looking for participantsNCT07148791
What this trial is testing

Exploratory Study of Anti-BCMA-CD19 CAR-T Cell Therapy in Relapsed or Refractory IgG4-Related Disease

Who this might be right for
IgG4 Related DiseaseB-cell Mediated Autoimmune Disorders
Chinese PLA General Hospital 9
Large-scale testing (Phase 3)Study completedNCT03217422
What this trial is testing

ADCC Mediated B-Cell dEpletion and BAFF-R Blockade

Who this might be right for
Autoimmune Hepatitis
Novartis Pharmaceuticals 68
Early research (Phase 1)Looking for participantsNCT06680037
What this trial is testing

Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders

Who this might be right for
B-cell Mediated Autoimmune Disorders
TG Therapeutics, Inc. 100