Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “BRAF V600E”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Not applicableEnded earlyNCT03593993
What this trial is testing

A Biospecimen Collection Study in BRAF-V600E Mutated Recurrent Gliomas

Who this might be right for
GliomaBRAF V600EPleomorphic Xantho-Astrocytoma+1 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 3
Testing effectiveness (Phase 2)Ended earlyNCT01754376
What this trial is testing

Combined BRAF-Targeted Therapy & Immunotherapy for Melanoma

Who this might be right for
Melanoma
Massachusetts General Hospital 6
Testing effectiveness (Phase 2)Study completedNCT03693170
What this trial is testing

Encorafenib, Binimetinib and Cetuximab in Subjects With Previously Untreated BRAF-mutant ColoRectal Cancer

Who this might be right for
BRAF V600E-mutant Metastatic Colorectal Cancer
Pierre Fabre Medicament 95
Testing effectiveness (Phase 2)Ended earlyNCT05926960
What this trial is testing

A Study Comparing 3 Study Medicines (Encorafenib, Binimetinib, Pembrolizumab) to 2 Study Medicines (Ipilimumab and Nivolumab) in Patients With Advanced Melanoma

Who this might be right for
Melanoma
Pfizer 38
Testing effectiveness (Phase 2)UnknownNCT05263453
What this trial is testing

HL-085+Vemurafenib to Treat Advanced Melanoma Patients With BRAF V600E/K Mutation

Who this might be right for
Melanoma
Shanghai Kechow Pharma, Inc. 104
Early research (Phase 1)Ended earlyNCT01940809
What this trial is testing

Ipilimumab With or Without Dabrafenib, Trametinib, and/or Nivolumab in Treating Patients With Melanoma That Is Metastatic or Cannot Be Removed by Surgery

Who this might be right for
BRAF V600E Mutation PresentBRAF V600K Mutation PresentMetastatic Melanoma+5 more
National Cancer Institute (NCI) 15
Testing effectiveness (Phase 2)Study completedNCT02281760
What this trial is testing

Dabrafenib and Trametinib in People With BRAF V600E Mutation Positive Lesions in Erdheim Chester Disease

Who this might be right for
BRAF V600E Mutation
National Human Genome Research Institute (NHGRI) 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439292
What this trial is testing

Testing Trametinib and Dabrafenib as a Potential Targeted Treatment in Cancers With BRAF Genetic Changes (MATCH-Subprotocol H)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 44
Testing effectiveness (Phase 2)Active Not RecruitingNCT04117945
What this trial is testing

Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer

Who this might be right for
BRAF V600E NegativeKRAS Gene Mutation NegativeLocally Advanced Unresectable Colorectal Adenocarcinoma+10 more
Academic and Community Cancer Research United 22
Testing effectiveness (Phase 2)Looking for participantsNCT06411600
What this trial is testing

Combination Therapy for BRAF-V600E Metastatic CRCm

Who this might be right for
Metastatic Colorectal Cancer
Vall d'Hebron Institute of Oncology 94
Testing effectiveness (Phase 2)Looking for participantsNCT06887088
What this trial is testing

Encorafenib and biNimetinib Followed by CEmiplimab and FiAnLimab in Patients With BRAF Mutant melanOma and Symptomatic Brain Metastases

Who this might be right for
Melanoma BRAF V600E/K MutatedMelanoma and Brain Metastases
Grupo Español Multidisciplinar de Melanoma 33
Testing effectiveness (Phase 2)Study completedNCT04452877
What this trial is testing

Dabrafenib in Combination With Trametinib in Chinese Patients With BRAF V600E Mutant Metastatic NSCLC

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Novartis Pharmaceuticals 40
Early research (Phase 1)Study completedNCT01791309
What this trial is testing

Vemurafenib and Panitumumab Combination Therapy in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Memorial Sloan Kettering Cancer Center 16
Post-approval studies (Phase 4)WithdrawnNCT07092410
What this trial is testing

Surgical or Radiotherapeutic Intervention Concerning Large Singular Stable to Progressive Metastases in Patients With BRAFV600-mutated Melanoma Receiving Treatment With Encorafenib + Binimetinib

Who this might be right for
Melanoma BRAF V600E/K Mutated
SRH Wald-Klinikum Gera GmbH
Testing effectiveness (Phase 2)Study completedNCT02039947
What this trial is testing

Study to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the Brain

Who this might be right for
Melanoma and Brain Metastases
Novartis Pharmaceuticals 127
Testing effectiveness (Phase 2)Active Not RecruitingNCT06967155
What this trial is testing

Irinotecan With Dabrafenib Plus Trametinib and Anti-EGFR in the Second Line of Therapy in People With Metastatic Colorectal Cancer

Who this might be right for
Neoplasms
Blokhin's Russian Cancer Research Center 23
Early research (Phase 1)Ended earlyNCT04044430
What this trial is testing

Encorafenib, Binimetinib, and Nivolumab in Treating Microsatellite Stable BRAF V600E Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colon AdenocarcinomaMetastatic Colorectal AdenocarcinomaMetastatic Microsatellite Stable Colorectal Carcinoma+25 more
University of California, San Francisco 2
Not applicableNot Yet RecruitingNCT07007689
What this trial is testing

A Multi-omics Study of BRAF V600E Mutant Colorectal Cancer

Who this might be right for
BRAF V600E-mutant Metastatic Colorectal Cancer
Sun Yat-sen University 200
Large-scale testing (Phase 3)Active Not RecruitingNCT04657991
What this trial is testing

A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma

Who this might be right for
Melanoma
Pfizer 257
Testing effectiveness (Phase 2)Study completedNCT01750918
What this trial is testing

BRAF/MEK/EGFR Inhibitor Combination Study in Colorectal Cancer (CRC)

Who this might be right for
Cancer
Novartis Pharmaceuticals 166
Next Page