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Results for “BRCA Mutated Breast Cancer”

110 trials

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Showing 20 of 110 results

Early research (Phase 1)Active Not RecruitingNCT04673448
What this trial is testing

Niraparib and TSR-042 for the Treatment of BRCA-Mutated Unresectable or Metastatic Breast, Pancreas, Ovary, Fallopian Tube, or Primary Peritoneal Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8BRCA-Associated Malignant Neoplasm+24 more
University of Washington 18
Not applicableStudy completedNCT04257474
What this trial is testing

Barriers to Screening Breast MRI Utilization Among Patients at Elevated Risk

Who this might be right for
Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute 265
Large-scale testing (Phase 3)Study completedNCT02163694
What this trial is testing

Randomized, Placebo-controlled Trial of Carboplatin and Paclitaxel With or Without Veliparib (ABT-888) in HER2-negative Metastatic or Locally Advanced Unresectable BRCA-associated Breast Cancer

Who this might be right for
Metastatic Breast Cancer
AbbVie 513
Not applicableStudy completedNCT02197000
What this trial is testing

A Nutritional Intervention to Decrease Breast Density Among Female BRCA (BReast CAncer Susceptibility Gene) Carriers

Who this might be right for
BRCA1 Gene MutationBRCA2 Gene Mutation
Rabin Medical Center 23
Large-scale testing (Phase 3)Looking for participantsNCT06952803
What this trial is testing

Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

Who this might be right for
Prostate Cancer
AstraZeneca 700
Not applicableStudy completedNCT06484725
What this trial is testing

Oncotype DX in BRCA-mutated Breast Cancer Patients: Our Experience. A Retrospective Observational Monocentric Study

Who this might be right for
Breast CancerGenetic Predisposition
IRCCS San Raffaele 250
Testing effectiveness (Phase 2)WithdrawnNCT05554211
What this trial is testing

Tranexamic Acid Usage in Bilateral Mastectomy to Reduce Post-surgical Drainage

Who this might be right for
Breast CancerBRCA Mutation
Northwestern University
Testing effectiveness (Phase 2)Study completedNCT02595905
What this trial is testing

Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases

Who this might be right for
Metastatic BRCA Hereditary Breast CarcinomaMetastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Brain+3 more
National Cancer Institute (NCI) 344
Not applicableEnded earlyNCT04436120
What this trial is testing

Treatment Resistance Following Anti-cancer Therapies

Who this might be right for
Disease Progression
Pfizer 38
Not applicableLooking for participantsNCT03667417
What this trial is testing

Genetic Predisposition to Breast and Ovarian Cancer: Prospective Study of BRCAx Gene Mutation

Who this might be right for
Breast CancersOvarian Cancers
Institut Paoli-Calmettes 5,000
Not applicableActive Not RecruitingNCT07821229
What this trial is testing

Combination of Mitomycin and Carboplatin in Neoadjuvant Therapy in BRCA-associated Triple-negative Locally Advanced Breast Cancer

Who this might be right for
Breast Cancer (Early Breast Cancer)BRCA 1 Gene MutationBRCA 2 Gene Mutation
N.N. Petrov National Medical Research Center of Oncology 30
Large-scale testing (Phase 3)Study completedNCT01945775
What this trial is testing

A Study Evaluating Talazoparib (BMN 673), a PARP Inhibitor, in Advanced and/or Metastatic Breast Cancer Patients With BRCA Mutation (EMBRACA Study)

Who this might be right for
Breast NeoplasmsBRCA 1 Gene MutationBRCA 2 Gene Mutation
Pfizer 431
Early research (Phase 1)Study completedNCT05258747
What this trial is testing

A Crossover Bioequivalence Study of Olaparib Tablets, 150 mg (Lek Pharmaceuticals d.d.) and Lynparza® (Olaparib) Tablets 150 mg (AstraZeneca Pharmaceuticals LP), in Patients With Breast Cancer Gene (BRCA) Mutated Ovarian Cancer, Recurrent Ovarian Cancer or Metastatic Breast Cancer

Who this might be right for
Ovarian CancerBreast Cancer
Sandoz 70
Early research (Phase 1)Study completedNCT00892736
What this trial is testing

Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy

Who this might be right for
Basal-Like Breast CarcinomaBRCA1 Mutation CarrierBRCA2 Mutation Carrier+14 more
National Cancer Institute (NCI) 98
Testing effectiveness (Phase 2)UnknownNCT00080756
What this trial is testing

Deslorelin Combined With Low-Dose Add-Back Estradiol and Testosterone in Preventing Breast Cancer in Premenopausal Women Who Are at High Risk for This Disease

Who this might be right for
brca1 Mutation Carrierbrca2 Mutation CarrierBreast Cancer
City of Hope Medical Center 11
Not applicableUnknownNCT01329068
What this trial is testing

Patient Empowerment by Group Medical Consultations

Who this might be right for
Breast CancerBRCA Mutation
Radboud University Medical Center 320
Large-scale testing (Phase 3)Study completedNCT02000622
What this trial is testing

Assessment of the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations.

Who this might be right for
Breast Cancer MetastaticBRCA 1 Gene MutationBRCA 2 Gene Mutation
AstraZeneca 302
Testing effectiveness (Phase 2)Study completedNCT01367639
What this trial is testing

Trial of Inquiry Based Stress Reduction (IBSR) Program for BRCA1/2 Mutation Carriers

Who this might be right for
Hereditary Breast and Ovarian Cancer Syndrome
Sheba Medical Center 67
Testing effectiveness (Phase 2)Study completedNCT01670500
What this trial is testing

Cisplatin vs. Doxorubicin/Cyclophosphamide in BrCa

Who this might be right for
Breast Cancer
Beth Israel Deaconess Medical Center 118
Large-scale testing (Phase 3)Active Not RecruitingNCT04915755
What this trial is testing

Efficacy and Safety Comparison of Niraparib to Placebo in Participants With Human Epidermal Growth Factor 2 Negative (HER2-) Breast Cancer Susceptibility Gene Mutation (BRCAmut) or Triple-Negative Breast Cancer (TNBC) With Molecular Disease

Who this might be right for
Neoplasms, Breast
GlaxoSmithKline 40
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