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Results for “BRCA-Associated Breast Carcinoma”

18 trials

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Showing 18 of 18 results

Not applicableLooking for participantsNCT07617025
What this trial is testing

Prognostic and Predictive Role of Intrinsic Molecular Subtypes in BRCA-associated Breast Cancer

Who this might be right for
Breast Cancer
Angela Toss 100
Testing effectiveness (Phase 2)Study completedNCT01525589
What this trial is testing

A Phase II Clinical Trial of PM01183 in BRCA 1/2-Associated or Unselected Metastatic Breast Cancer

Who this might be right for
Breast Cancer
PharmaMar 111
Testing effectiveness (Phase 2)Study completedNCT01149083
What this trial is testing

Veliparib With or Without Carboplatin in Treating Patients With Stage III or IV Breast Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Locally Advanced Breast Carcinoma+2 more
National Cancer Institute (NCI) 77
Testing effectiveness (Phase 2)Active Not RecruitingNCT02393794
What this trial is testing

Cisplatin Plus Romidepsin & Nivolumab in Locally Recurrent or Metastatic Triple Negative Breast Cancer (TNBC)

Who this might be right for
Triple-Negative Breast CancerBreast Cancer
Priyanka Sharma 51
Early research (Phase 1)Study completedNCT01104259
What this trial is testing

Veliparib, Cisplatin, and Vinorelbine Ditartrate in Treating Patients With Recurrent and/or Metastatic Breast Cancer

Who this might be right for
Estrogen Receptor-negative Breast CancerHER2-negative Breast CancerHereditary Breast/Ovarian Cancer - BRCA1+6 more
University of Washington 50
Testing effectiveness (Phase 2)Study completedNCT00494234
What this trial is testing

Study to Assess The Efficacy and Safety of a PARP Inhibitor For The Treatment of BRCA-positive Advanced Breast Cancer

Who this might be right for
Breast Neoplasms
AstraZeneca 54
Testing effectiveness (Phase 2)Looking for participantsNCT06516289
What this trial is testing

Neoadjuvant Treatment of gBRCA-Mutated HER2-Negative Breast Cancer With HRS-1167 and Famitinib ± Camrelizumab

Who this might be right for
BRCA-Mutated Breast CarcinomaHER2-negative Breast Cancer
Fudan University 130
Large-scale testing (Phase 3)Study completedNCT02163694
What this trial is testing

Randomized, Placebo-controlled Trial of Carboplatin and Paclitaxel With or Without Veliparib (ABT-888) in HER2-negative Metastatic or Locally Advanced Unresectable BRCA-associated Breast Cancer

Who this might be right for
Metastatic Breast Cancer
AbbVie 513
Testing effectiveness (Phase 2)Study completedNCT02595905
What this trial is testing

Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases

Who this might be right for
Metastatic BRCA Hereditary Breast CarcinomaMetastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Brain+3 more
National Cancer Institute (NCI) 344
Not applicableUnknownNCT05763472
What this trial is testing

Breast Cancer After Ovarian Cancer During and/or After Therapy: Genomic Evaluation

Who this might be right for
BRCA-Associated Breast Carcinoma
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 10
Not applicableActive Not RecruitingNCT07821229
What this trial is testing

Combination of Mitomycin and Carboplatin in Neoadjuvant Therapy in BRCA-associated Triple-negative Locally Advanced Breast Cancer

Who this might be right for
Breast Cancer (Early Breast Cancer)BRCA 1 Gene MutationBRCA 2 Gene Mutation
N.N. Petrov National Medical Research Center of Oncology 30
Testing effectiveness (Phase 2)WithdrawnNCT05209529
What this trial is testing

Chemo-free BRCA-targeted Neoadjuvant Strategy

Who this might be right for
TNBC - Triple-Negative Breast CancerBRCA1 MutationBRCA2 Mutation
European Organisation for Research and Treatment of Cancer - EORTC
Early research (Phase 1)Study completedNCT03685331
What this trial is testing

HOPE: Olaparib, Palbociclib and Fulvestrant in Patients With BRCA Mutation-associated, HR+, HER2-metastatic Breast Cancer

Who this might be right for
Metastatic Breast CancerLocally Advanced Breast CancerAdvanced Breast Cancer+2 more
Abramson Cancer Center at Penn Medicine 9
Testing effectiveness (Phase 2)Looking for participantsNCT05485766
What this trial is testing

Novel Neoadjuvant and Adjuvant Strategy for Germline BRCA 1/2 Mutated Triple Negative Breast Cancer

Who this might be right for
Triple Negative Breast NeoplasmsTriple Negative Breast CancerBreast Neoplasms+5 more
Okayama University 23
Not applicableLooking for participantsNCT06760507
What this trial is testing

Evaluating an Evidence-Based Family History Screening Program Adapted to Increase Reach and Uptake of Screening for BRCA-Associated Cancers in Rural Public Health Clinics

Who this might be right for
Breast CancerOvarian Cancer
Emory University 3,209
Not applicableNo Longer AvailableNCT02985658
What this trial is testing

Expanded Access With ABT-888 (Veliparib) to Treat Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer With BRCA 1 or BRCA 2 Genetic MutationTriple-Negative Breast Cancer
University of Washington
Testing effectiveness (Phase 2)Ended earlyNCT06065059
What this trial is testing

Study to Evaluate TNG348 Alone and With a PARP Inhibitor in Patients With BRCA 1/2 Mutant or HRD+ Solid Tumors

Who this might be right for
Breast CancerOvarian CancerPancreas Cancer+5 more
Tango Therapeutics, Inc. 7
Early research (Phase 1)Active Not RecruitingNCT04673448
What this trial is testing

Niraparib and TSR-042 for the Treatment of BRCA-Mutated Unresectable or Metastatic Breast, Pancreas, Ovary, Fallopian Tube, or Primary Peritoneal Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8BRCA-Associated Malignant Neoplasm+24 more
University of Washington 18