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Results for “BRCA1/2 Mutation”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT01445418
What this trial is testing

AZD2281 Plus Carboplatin to Treat Breast and Ovarian Cancer

Who this might be right for
Breast CancerOvarian Cancer
National Cancer Institute (NCI) 103
Not applicableNot Yet RecruitingNCT06726330
What this trial is testing

Risk-reducing Strategies, Including Fimbriectomy, in Women With a Germline Mutation Predisposing to Ovarian or Pelvic Cancer

Who this might be right for
Tubo-ovarian CarcinomaHigh-grade Serous CarcinomaPrimary Peritoneal Carcinoma Stage III+2 more
Centre Oscar Lambret 1,100
Early research (Phase 1)Active Not RecruitingNCT04367675
What this trial is testing

INO 5401 Vaccination in BRCA1/2 Mutation Carriers

Who this might be right for
BRCA1/2 Mutation
Abramson Cancer Center at Penn Medicine 44
Not applicableLooking for participantsNCT02478892
What this trial is testing

Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

Who this might be right for
Pancreatic Cancer
Abramson Cancer Center at Penn Medicine 200
Testing effectiveness (Phase 2)Study completedNCT03117933
What this trial is testing

Olaparib +/- Cediranib or Chemotherapy in Patients With Platinum-resistant Ovarian Cancer

Who this might be right for
Ovarian Cancer
University of Oxford 139
Not applicableLooking for participantsNCT03396341
What this trial is testing

Responses to Genetic Risk Modifier Testing Among Women With Pathogenic Variants in Breast Cancer Predisposition Genes

Who this might be right for
Genetic TestingBRCA1/2
Memorial Sloan Kettering Cancer Center 806
Not applicableLooking for participantsNCT07292246
What this trial is testing

A Prospective CohorT Study of HandX - Assisted ENdoscopic MAstectomy: Feasibility and Safety (ATHENA I Study)

Who this might be right for
Breast CancerBRCA 1 Gene MutationBRCA 2 Gene Mutation+5 more
Vasileios Kalles 15
Testing effectiveness (Phase 2)Study completedNCT02401347
What this trial is testing

Phase II Trial of Talazoparib in BRCA1/2 Wild-type HER2-negative Breast Cancer and Other Solid Tumors

Who this might be right for
Advanced Breast CancerHER2/Neu NegativeTriple-Negative Breast Cancer
Melinda Telli 21
Not applicableStudy completedNCT02963688
What this trial is testing

BRCA 1/2 Mutation in Korean Patients With Epithelial Ovarian Cancer

Who this might be right for
To Investigate the Prevalence of BRCA 1/2 Mutation Among Ovarian Cancer
Samsung Medical Center 298
Not applicableStudy completedNCT03211611
What this trial is testing

Management of Women With BRCA1/2 Mutation

Who this might be right for
BRCA1 MutationBRCA2 Mutation
University Hospital, Montpellier 600
Not applicableStudy completedNCT02087592
What this trial is testing

Feasibility of Lifestyle Intervention in BRCA1/2 Mutation Carriers

Who this might be right for
Hereditary Breast and Ovarian Cancer
Technical University of Munich 69
Not applicableUnknownNCT05857670
What this trial is testing

Psyco Quality of Life and Procreation BRCA1/2

Who this might be right for
Breast CancerGenetic Predisposition
Regina Elena Cancer Institute 200
Testing effectiveness (Phase 2)Study completedNCT03009682
What this trial is testing

Olaparib Monotherapy in Relapsed Small Cell Lung Cancer Patients With HR Pathway Gene Mutations Not Limited to BRCA 1/2 Mutations, ATM Deficiency or MRE11A Mutations

Who this might be right for
Small Cell Lung Cancer
Samsung Medical Center 15
Large-scale testing (Phase 3)Study completedNCT03286842
What this trial is testing

To Study Clinical Effectiveness and Safety of Olaparib Monotherapy in Metastatic Breast Cancer Patients.

Who this might be right for
HER2-ve Metastatic Breast CancerGermline BRCA1/2 MutationsSomatic BRCA1/2 Mutations
AstraZeneca 256
Not applicableUnknownNCT01907438
What this trial is testing

Transformation Potential of E2 Exposed Breast Cancer Susceptibility Gene Mutation Heterozygous Epithelial Breast Cells

Who this might be right for
BRCA1 Gene MutationBRCA2 Gene Mutation
Hadassah Medical Organization 30
Not applicableLooking for participantsNCT05769517
What this trial is testing

Prediction of Germline BRCA 1/2 Genes From Healthy Ovaries

Who this might be right for
BRCA MutationOvarian CancerUltrasound Therapy; Complications
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 6,465
Large-scale testing (Phase 3)Study completedNCT02000622
What this trial is testing

Assessment of the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations.

Who this might be right for
Breast Cancer MetastaticBRCA 1 Gene MutationBRCA 2 Gene Mutation
AstraZeneca 302
Not applicableStudy completedNCT04987931
What this trial is testing

Real-World Outcomes of US Talazoparib-Treated Patients With Locally Advanced or Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Pfizer 84
Not applicableUnknownNCT04368442
What this trial is testing

Cohort Study of Patients With HER2-negative MBC and BRCA 1/2 Pathogenic Mutation

Who this might be right for
Breast Cancer Metastatic
Samsung Medical Center 583
Early research (Phase 1)Study completedNCT01339650
What this trial is testing

Study of ABT-767 in Subjects With Breast Cancer 1 and Breast Cancer 2 (BRCA 1 and BRCA 2) Mutations and Solid Tumors or High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Who this might be right for
Fallopian TubePrimary Peritoneal CancerSolid Tumors (e.g. Breast, Ovarian, Prostate, or Pancreatic) and Ovarian
AbbVie (prior sponsor, Abbott) 93
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