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Results for “BRCA1 Hereditary Breast and Ovarian Cancer Syndrome”

36 trials

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Showing 20 of 36 results

Not applicableEnded earlyNCT04668521
What this trial is testing

Multifactorial Risk Assessment for Breast & Ovarian Cancer Risk Detection

Who this might be right for
Adnexal MassGermline BRCA1 Gene MutationGermline BRCA2 Gene Mutation+1 more
Aspira Women's Health 215
Testing effectiveness (Phase 2)Ended earlyNCT02203513
What this trial is testing

A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer

Who this might be right for
Ovarian CancerBreast CancerProstate Cancer
National Cancer Institute (NCI) 111
Not applicableLooking for participantsNCT03702309
What this trial is testing

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

Who this might be right for
CancerBreast CancerLung Cancer+15 more
University Health Network, Toronto 2,500
Large-scale testing (Phase 3)Study completedNCT00685256
What this trial is testing

Standard Genetic Counseling With or Without a Decision Guide in Improving Communication Between Mothers Undergoing BRCA1/2 Testing and Their Minor-Age Children

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, brca2)
Georgetown University 245
Not applicableNot Yet RecruitingNCT07236359
What this trial is testing

Evaluation of Well Being and Patient Reported Outcomes After Robotic Single-port Nipple Sparing Mastectomy and Implant Reconstruction

Who this might be right for
Breast ReconstructionBreast CancerHereditary Breast/Ovarian Cancer (brca1, brca2)+1 more
Beaumont Hospital 108
Early research (Phase 1)Study completedNCT00892736
What this trial is testing

Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy

Who this might be right for
Basal-Like Breast CarcinomaBRCA1 Mutation CarrierBRCA2 Mutation Carrier+14 more
National Cancer Institute (NCI) 98
Not applicableStudy completedNCT02451735
What this trial is testing

Genetic Counseling for Breast Cancer Survivors (GC for BC)

Who this might be right for
Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute 157
Not applicableStudy completedNCT06534424
What this trial is testing

Clinical Impact of Enhanced Risk Assessments in Women With a BRCA1/2 Mutation, CARE Study

Who this might be right for
BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome
Ohio State University Comprehensive Cancer Center 152
Not applicableStudy completedNCT00040222
What this trial is testing

Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer

Who this might be right for
Familial Ovarian CancerFamilial Breast CancerBRCA1-associate Malignancies+1 more
National Cancer Institute (NCI) 377
Testing effectiveness (Phase 2)Study completedNCT00253539
What this trial is testing

Arzoxifene or Tamoxifen in Preventing Breast Cancer in Premenopausal Women at High Risk for Breast Cancer

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, brca2)
The Cleveland Clinic 3
Not applicableActive Not RecruitingNCT02760849
What this trial is testing

Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations

Who this might be right for
Deleterious BARD1 Gene MutationDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene Mutation+11 more
M.D. Anderson Cancer Center 374
Not applicableLooking for participantsNCT04494945
What this trial is testing

Identifying and Caring for Individuals With Inherited Cancer Syndrome

Who this might be right for
BRCA1/2-Associated Hereditary Breast and Ovarian Cancer SyndromeBreast Ductal Carcinoma In SituHematopoietic and Lymphoid System Neoplasm+3 more
OHSU Knight Cancer Institute 27,500
Not applicableEnrolling By InvitationNCT07381985
What this trial is testing

Strategy for Management of Patients With Hereditary Cancer Syndromes (HCS) in a Rural Environment

Who this might be right for
Hereditary Cancer SyndromesBRCA1 Hereditary Breast and Ovarian Cancer SyndromeLynch Syndrome
University of Vermont Medical Center 200
Not applicableActive Not RecruitingNCT01608074
What this trial is testing

Radical Fimbriectomy for Young BRCA Mutation Carriers

Who this might be right for
BRCA1 MutationBRCA2 MutationHereditary Breast and Ovarian Cancer
Centre Oscar Lambret 123
Testing effectiveness (Phase 2)Study completedNCT01333748
What this trial is testing

Search Allelic Imbalance of Expression of BRCA Genes in Hereditary Risk of Breast and/or Ovarian Cancer

Who this might be right for
Hereditary Breast and Ovarian Cancer Syndrome
Centre Francois Baclesse 530
Not applicableUnknownNCT01273909
What this trial is testing

Outcomes After Perforator Flap Reconstruction for Breast Reconstruction and/or Lymphedema Treatment

Who this might be right for
Breast CancerHereditary Breast/Ovarian Cancer (brca1, brca2)Acquired Lymphedema+1 more
The National Institute of Lymphology 1,000
Not applicableUnknownNCT05409222
What this trial is testing

Study of Quality of Life Post Salpingo-oophorectomy in BRCA1/2 & PALB2 Mutation Carriers (BRCA-HRT)

Who this might be right for
Hereditary Breast and Ovarian Cancer
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 45
Not applicableLooking for participantsNCT06726642
What this trial is testing

CfDNA in Hereditary And High-risk Malignancies 2

Who this might be right for
Hereditary Cancer Syndrome
University Health Network, Toronto 1,000
Not applicableNot Yet RecruitingNCT07542405
What this trial is testing

A Web-Based Program (Kindred) to Improve the Understanding of Genetic Cancer Risk and Cancer Genetic Testing in African American Families

Who this might be right for
BRCA1-Related Hereditary Breast and Ovarian Cancer SyndromeBRCA2-Related Hereditary Breast and Ovarian Cancer SyndromeHereditary Neoplastic Syndrome+1 more
University of Michigan Rogel Cancer Center 150
Testing effectiveness (Phase 2)Study completedNCT02978495
What this trial is testing

Neoadjuvant Carboplatin in Triple Negative Breast Cancer

Who this might be right for
BRCA1 Hereditary Breast and Ovarian Cancer Syndrome
Barretos Cancer Hospital 154
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