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Results for “BRCA1 Protein”

13 trials

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Showing 13 of 13 results

Not applicableWithdrawnNCT02526719
What this trial is testing

Nipple Delay Prior to Nipple Sparing Mastectomy: A Pilot RCT

Who this might be right for
Breast Cancer
University Health Network, Toronto
Testing effectiveness (Phase 2)Ended earlyNCT00589238
What this trial is testing

Paclitaxel, Doxorubicin, and Cyclophosphamide With Or Without Carboplatin in Treating Women With Locally Advanced Breast Cancer That Can Be Removed by Surgery

Who this might be right for
Breast Cancer
National Cancer Centre, Singapore 16
Testing effectiveness (Phase 2)Looking for participantsNCT05485766
What this trial is testing

Novel Neoadjuvant and Adjuvant Strategy for Germline BRCA 1/2 Mutated Triple Negative Breast Cancer

Who this might be right for
Triple Negative Breast NeoplasmsTriple Negative Breast CancerBreast Neoplasms+5 more
Okayama University 23
Testing effectiveness (Phase 2)Study completedNCT00628251
What this trial is testing

Dose-finding Study Comparing Efficacy and Safety of a PARP Inhibitor Against Doxil in BRCA+ve Advanced Ovarian Cancer

Who this might be right for
Ovarian Neoplasms
AstraZeneca 97
Testing effectiveness (Phase 2)Study completedNCT00494442
What this trial is testing

Study to Assess the Efficacy and Safety of a PARP Inhibitor for the Treatment of BRCA-positive Advanced Ovarian Cancer

Who this might be right for
Ovarian Neoplasm
AstraZeneca 58
Testing effectiveness (Phase 2)Study completedNCT00494234
What this trial is testing

Study to Assess The Efficacy and Safety of a PARP Inhibitor For The Treatment of BRCA-positive Advanced Breast Cancer

Who this might be right for
Breast Neoplasms
AstraZeneca 54
Early research (Phase 1)Study completedNCT00516373
What this trial is testing

Assess the Safety and Pharmacokinetics of an Inhibitor of Poly ADP-Ribose Polymerase-1 (PARP)

Who this might be right for
Ovarian NeoplasmsBRCA1 ProteinBRCA2 Protein
AstraZeneca 98
Early research (Phase 1)UnknownNCT01022333
What this trial is testing

The Potential for Oral Diindolylmethane (DIM) Supplementation to Increase the Production of the BRCA1 Protein in BRCA1 Mutation Carriers

Who this might be right for
Breast Cancer
Women's College Hospital 300
Testing effectiveness (Phase 2)Ended earlyNCT01990352
What this trial is testing

Correlate BRCA1 Protein Expression With Response to DNA Damaging Chemotherapy

Who this might be right for
Breast Cancer
University of Arizona 24
Early research (Phase 1)Study completedNCT05904730
What this trial is testing

Phase I Clinical Trials Investigating the Potential Efficacy of Axitinib in Patients With a BRCA 1/2 Mutations

Who this might be right for
Breast CancerOvarian CancerBreast Neoplasms+5 more
Lynkcell Europe 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439227
What this trial is testing

Testing AZD1775 as a Potential Targeted Treatment in Cancers With BRCA Genetic Changes (MATCH-Subprotocol Z1I)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 35
Early research (Phase 1)Study completedNCT01286987
What this trial is testing

Study of Talazoparib, a PARP Inhibitor, in Patients With Advanced or Recurrent Solid Tumors

Who this might be right for
Advanced or Recurrent Solid TumorsBreast NeoplasmsOvarian Cancer, Epithelial+4 more
Pfizer 113
Not applicableUnknownNCT02959398
What this trial is testing

Evaluation of Tomosynthesis for Characterization and the Management of Breast Lesions

Who this might be right for
Breast NeoplasmsTomosynthesisBRCA1 Protein+1 more
Assistance Publique - Hôpitaux de Paris 2,000