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Results for “BTK Inhibitors”

31 trials

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Showing 20 of 31 results

Testing effectiveness (Phase 2)UnknownNCT04831658
What this trial is testing

A Prospective Clinical Study of BTK Inhibitor, PD-1 and Formustine in the First-line Treatment of Primary Central Nervous System Lymphoma

Who this might be right for
Primary Central Nervous System Lymphoma
Mingzhi Zhang 40
Not applicableUnknownNCT06130709
What this trial is testing

IRAF-ABLATION Study: a Multicenter International Retrospective Cohort of Patients With BTK Inhibitors-related AF Treated by Catheter Ablation

Who this might be right for
BTKi-induced Atrial FibrillationHematologic MalignancyAtrial Fibrillation Catheter Ablation
University Hospital, Caen 100
Testing effectiveness (Phase 2)Looking for participantsNCT07371923
What this trial is testing

Application of Zanubrutinib-based Combination Regimens in the Treatment of Newly-diagnosed Diffuse Large B-cell Lymphoma

Who this might be right for
Diffuse Large B Cell Lymphoma (DLBCL)
Beijing Tongren Hospital 50
Not applicableStudy completedNCT04938141
What this trial is testing

MEOI and HRQoL in CLL Patients Treated With BTKis

Who this might be right for
Chronic Lymphocytic Leukemia
AstraZeneca 23
Large-scale testing (Phase 3)Looking for participantsNCT06846671
What this trial is testing

BGB-16673 Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors

Who this might be right for
CLLChronic Lymphocytic Leukemia
BeOne Medicines 250
Not applicableUnknownNCT05495828
What this trial is testing

Orelabrutinib Therapy in Patients With r/r B-cell Lymphoma Intolerant to Other Bruton Tyrosine Kinase Inhibitors

Who this might be right for
B-cell Lymphoma
Peking University People's Hospital 30
Not applicableNot Yet RecruitingNCT07283965
What this trial is testing

Zanubrutinib and Acalabrutinib Use and Risk of Atrial Fibrillation in Patients With Chronic B-cell Malignancies

Who this might be right for
Chronic B-cell MalignanciesBTK InhibitorsCardiovascular Diseases
University Hospital, Caen 15,000
Not applicableActive Not RecruitingNCT04882475
What this trial is testing

Biological Insights of First Relapsed-refractory Patients With Mantle Cell Lymphoma: the MANTLE-FIRST BIO Study.

Who this might be right for
Mantle Cell Lymphoma
Fondazione Italiana Linfomi - ETS 160
Not applicableLooking for participantsNCT06151730
What this trial is testing

Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study

Who this might be right for
Chronic Lymphocytic LeukemiaHematopoietic and Lymphoid System NeoplasmMantle Cell Lymphoma+2 more
Mayo Clinic 100
Not applicableLooking for participantsNCT06508684
What this trial is testing

Current Status of BTKi Treatment for CLL/SLL in China

Who this might be right for
CLL/SLL
The First Affiliated Hospital with Nanjing Medical University 1,000
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06890585
What this trial is testing

Zanubrutinib, Chidamide, and Rituximab Induction With or Without CHOP Versus R-CHOP in Newly Diagnosed Double-Expressor DLBCL

Who this might be right for
BTK InhibitorsHistone Deacetylase InhibitorDouble Express Diffuse Large B-cell Lymphoma
Li Zhiming 128
Not applicableEnrolling By InvitationNCT06211413
What this trial is testing

Hypertension and Arrhythmias in CLL Patients Treated With BTK Inhibitors

Who this might be right for
Chronic Lymphocytic LeukemiaAtrial FibrillationHypertension+1 more
Abramson Cancer Center at Penn Medicine 50
Not applicableActive Not RecruitingNCT06561243
What this trial is testing

Ibrutinib and Acalabrutinib Use and Risk of Atrial Fibrillation in Patients With Chronic B-cell Malignancies

Who this might be right for
Chronic B-cell MalignanciesBTK InhibitorsCardiovascular Diseases
University Hospital, Caen 15,000
Not applicableLooking for participantsNCT05724121
What this trial is testing

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)Waldenstr(SqrRoot)(Delta)m s MacroglobulinemiaMantle Cell Lymphoma+3 more
National Heart, Lung, and Blood Institute (NHLBI) 135
Testing effectiveness (Phase 2)Looking for participantsNCT05249959
What this trial is testing

Consolidation With Loncastuximab Tesirine After a Short Course of Immunochemotherapy in BTKi-treated (or Intolerant) Relapsed/Refractory Mantle Cell Lymphoma Patients.

Who this might be right for
Relapsed Mantle Cell LymphomaRefractory Mantle Cell Lymphoma
Fondazione Italiana Linfomi - ETS 49
Not applicableLooking for participantsNCT07099443
What this trial is testing

Determinants of the Response to BTK Degraders (BTKd) in Chronic Lymphocytic Leukemia

Who this might be right for
Chronic Lymphocytic LeukemiaBTK Degraders
Nantes University Hospital 60
Not applicableLooking for participantsNCT05643235
What this trial is testing

Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors

Who this might be right for
Atrial FibrillationSupraventricular ArrhythmiaVentricular Arrhythmias and Cardiac Arrest+2 more
Northwell Health 50
Large-scale testing (Phase 3)Study completedNCT03053440
What this trial is testing

A Study Comparing BGB-3111 and Ibrutinib in Participants With Waldenström's Macroglobulinemia (WM)

Who this might be right for
Waldenström's Macroglobulinemia
BeiGene 201
Testing effectiveness (Phase 2)Looking for participantsNCT04840602
What this trial is testing

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

Who this might be right for
Lymphoplasmacytic LymphomaWaldenstrom Macroglobulinemia
National Cancer Institute (NCI) 92
Not applicableNot Yet RecruitingNCT06029166
What this trial is testing

Subcutaneous Cardiac Monitoring of Patients With BTK Inhibitors

Who this might be right for
Atrial Fibrillation
University Hospital, Caen 100
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