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Results for “BTK Inhibitors”

33 trials

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Showing 20 of 33 results

Testing effectiveness (Phase 2)UnknownNCT04831658
What this trial is testing

A Prospective Clinical Study of BTK Inhibitor, PD-1 and Formustine in the First-line Treatment of Primary Central Nervous System Lymphoma

Who this might be right for
Primary Central Nervous System Lymphoma
Mingzhi Zhang 40
Very early researchStudy completedNCT03771157
What this trial is testing

Serologic Response to SHINGRIX Vaccine in Patients With CLL and WM Treated With BTK Inhibitors

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)Waldenstrom Macroglobulinemia (WM)
University of Rochester 33
Testing effectiveness (Phase 2)UnknownNCT03891355
What this trial is testing

Carfilzomib + Lenalidomide and Dexamethasone for BTK Inhibitors Relapsed-refractory or Intolerant MCL

Who this might be right for
Mantle Cell Lymphoma
Fondazione Italiana Linfomi - ETS 16
Not applicableStudy completedNCT04938141
What this trial is testing

MEOI and HRQoL in CLL Patients Treated With BTKis

Who this might be right for
Chronic Lymphocytic Leukemia
AstraZeneca 23
Not applicableLooking for participantsNCT05724121
What this trial is testing

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)Waldenstr(SqrRoot)(Delta)m s MacroglobulinemiaMantle Cell Lymphoma+3 more
National Heart, Lung, and Blood Institute (NHLBI) 135
Not applicableNot Yet RecruitingNCT07592481
What this trial is testing

Connected Blood Pressure Monitoring in Patients With Hematologic Malignancies Initiating Covalent BTK Inhibitors

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)Follicular Lymphoma ( FL)Waldenstrom Macroglobulinaemia+3 more
Centre Hospitalier de la côte Basque 40
Large-scale testing (Phase 3)Looking for participantsNCT06846671
What this trial is testing

BGB-16673 Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors

Who this might be right for
CLLChronic Lymphocytic Leukemia
BeOne Medicines 250
Not applicableStudy completedNCT05555979
What this trial is testing

Assess Change in Patient Experience in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Venetoclax Tablets + Intravenous Rituximab or Bruton's Tyrosine Kinase Inhibitors Tablets in the United Kingdom

Who this might be right for
Chronic Lymphocytic Leukemia
AbbVie 56
Not applicableActive Not RecruitingNCT06561243
What this trial is testing

Ibrutinib and Acalabrutinib Use and Risk of Atrial Fibrillation in Patients With Chronic B-cell Malignancies

Who this might be right for
Chronic B-cell MalignanciesBTK InhibitorsCardiovascular Diseases
University Hospital, Caen 15,000
Not applicableNot Yet RecruitingNCT07283965
What this trial is testing

Zanubrutinib and Acalabrutinib Use and Risk of Atrial Fibrillation in Patients With Chronic B-cell Malignancies

Who this might be right for
Chronic B-cell MalignanciesBTK InhibitorsCardiovascular Diseases
University Hospital, Caen 15,000
Not applicableLooking for participantsNCT05506410
What this trial is testing

A Clinical Study of Hanlikang and BTK Inhibitors in the Treatment of Newly Diagnosed Mantle Cell Lymphoma

Who this might be right for
Newly Diagnosed Mantle Cell Lymphoma
Zhengzhou University 100
Large-scale testing (Phase 3)Looking for participantsNCT06970743
What this trial is testing

BGB-16673 Compared to Investigator's Choice in Participants With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Covalent Bruton Tyrosine Kinase (BTK) Inhibitors

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
BeOne Medicines 150
Testing effectiveness (Phase 2)Looking for participantsNCT04840602
What this trial is testing

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

Who this might be right for
Lymphoplasmacytic LymphomaWaldenstrom Macroglobulinemia
National Cancer Institute (NCI) 92
Not applicableUnknownNCT05495828
What this trial is testing

Orelabrutinib Therapy in Patients With r/r B-cell Lymphoma Intolerant to Other Bruton Tyrosine Kinase Inhibitors

Who this might be right for
B-cell Lymphoma
Peking University People's Hospital 30
Large-scale testing (Phase 3)Study completedNCT03053440
What this trial is testing

A Study Comparing BGB-3111 and Ibrutinib in Participants With Waldenström's Macroglobulinemia (WM)

Who this might be right for
Waldenström's Macroglobulinemia
BeiGene 201
Not applicableUnknownNCT05284175
What this trial is testing

Orelabrutinib in Patients With AQP4-IgG Positive Neuromyelitis Optica Spectrum Disorder

Who this might be right for
Neuromyelitis Optica Spectrum Disorder
Peking Union Medical College Hospital 23
Not applicableUnknownNCT06130709
What this trial is testing

IRAF-ABLATION Study: a Multicenter International Retrospective Cohort of Patients With BTK Inhibitors-related AF Treated by Catheter Ablation

Who this might be right for
BTKi-induced Atrial FibrillationHematologic MalignancyAtrial Fibrillation Catheter Ablation
University Hospital, Caen 100
Testing effectiveness (Phase 2)Looking for participantsNCT07371923
What this trial is testing

Application of Zanubrutinib-based Combination Regimens in the Treatment of Newly-diagnosed Diffuse Large B-cell Lymphoma

Who this might be right for
Diffuse Large B Cell Lymphoma (DLBCL)
Beijing Tongren Hospital 50
Not applicableNot Yet RecruitingNCT07525817
What this trial is testing

A Real-World Study of Pirtobrutinib in cBTKi-Resistant/Intolerant Mature B-Cell Lymphoma

Who this might be right for
Mature B-Cell Lymphoma
Ou Bai, MD/PHD 40
Not applicableLooking for participantsNCT07099443
What this trial is testing

Determinants of the Response to BTK Degraders (BTKd) in Chronic Lymphocytic Leukemia

Who this might be right for
Chronic Lymphocytic LeukemiaBTK Degraders
Nantes University Hospital 60
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