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Results for “Bispecific”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT06841055
What this trial is testing

Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment

Who this might be right for
Non-small Cell Lung Cancer
BioNTech SE 60
Testing effectiveness (Phase 2)Looking for participantsNCT03526835
What this trial is testing

Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced/Metastatic Solid TumorsColorectal CancerGastric Cancer+5 more
Merus B.V. 560
Testing effectiveness (Phase 2)UnknownNCT05176665
What this trial is testing

EMB-01 in Patients With Advanced/Metastatic Gastrointestinal Cancers

Who this might be right for
NeoplasmsNeoplasm MetastasisMetastatic Gastrointestinal Carcinoid Tumor
Shanghai EpimAb Biotherapeutics Co., Ltd. 152
Early research (Phase 1)Study completedNCT03922204
What this trial is testing

Bispecific Antibody MCLA-145 in Patients With Advanced or Metastatic Malignancies

Who this might be right for
Advanced CancerSolid Tumor, AdultB-cell Lymphoma, Adult
Merus B.V. 72
Testing effectiveness (Phase 2)UnknownNCT06424821
What this trial is testing

Cadonilimab Plus Chemotherapy as First-line Treatment for PD-L1 Negative NSCLC

Who this might be right for
NSCLC
Shanghai Pulmonary Hospital, Shanghai, China 54
Early research (Phase 1)Study completedNCT05116007
What this trial is testing

Anti-PD-1 and VEGF Bispecific Antibody AK112 in Combination With Chemotherapy in Patients With ES-SCLC

Who this might be right for
SCLC, Extensive Stage
Akeso 35
Early research (Phase 1)Looking for participantsNCT06735664
What this trial is testing

Zanubrutinib in Combination With Odronextamab for the Treatment of Patients With Richter's Transformation

Who this might be right for
Recurrent Transformed Chronic Lymphocytic LeukemiaRefractory Transformed Chronic Lymphocytic LeukemiaRichter Syndrome+1 more
City of Hope Medical Center 23
Early research (Phase 1)Study completedNCT03219268
What this trial is testing

MGD013 in Patients With Unresectable or Metastatic Neoplasms

Who this might be right for
Advanced Solid TumorsHematologic NeoplasmsOvarian Cancer+7 more
MacroGenics 277
Large-scale testing (Phase 3)Active Not RecruitingNCT04722848
What this trial is testing

Sequential Treatment With Ponatinib and Blinatumomab vs Chemotherapy and Imatinib in Newly Diagnosed Adult Ph+ ALL

Who this might be right for
Acute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)ALL, AdultPhiladelphia-Positive ALL
Gruppo Italiano Malattie EMatologiche dell'Adulto 236
Testing effectiveness (Phase 2)Looking for participantsNCT05828511
What this trial is testing

A Window of Opportunity Trial to Learn if Linvoseltamab is Safe and Well Tolerated, and How Well it Works in Adult Participants With Recently Diagnosed Multiple Myeloma Who Have Not Already Received Treatment

Who this might be right for
Multiple Myeloma
Regeneron Pharmaceuticals 149
Early research (Phase 1)Study completedNCT00635596
What this trial is testing

Phase I Study of MT110 in Lung Cancer (Adenocarcinoma and Small Cell), Gastric Cancer or Adenocarcinoma of the Gastro-Esophageal Junction, Colorectal Cancer, Breast Cancer, Hormone-Refractory Prostate Cancer, and Ovarian Cancer

Who this might be right for
Solid Tumors
Amgen Research (Munich) GmbH 65
Testing effectiveness (Phase 2)WithdrawnNCT03501056
What this trial is testing

Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Lung Cancer

Who this might be right for
Advanced Lung Cancer
Fuda Cancer Hospital, Guangzhou
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06790212
What this trial is testing

Neoadjuvant CAPOX Plus Ivonescimab Versus CAPOX for Locally Advanced Colon Cancer

Who this might be right for
Colon Cancer
Sun Yat-sen University 168
Early research (Phase 1)Looking for participantsNCT06773481
What this trial is testing

BC008-1A Injection for Recurrent CNS WHO G4 Glioma

Who this might be right for
GliomaGlioma Tumor RecurrenceGlioma, Recurrent High Grade+2 more
Sichuan Luzhou Buchang Biopharmaceutical Co., Ltd. 40
Testing effectiveness (Phase 2)Ended earlyNCT04735575
What this trial is testing

A Ph1/2 Study of EMB-06 in Participants With Relapsed or Refractory Myeloma

Who this might be right for
Relapsed or Refractory Multiple Myeloma
Shanghai EpimAb Biotherapeutics Co., Ltd. 40
Early research (Phase 1)Looking for participantsNCT07473726
What this trial is testing

A Phase I Clinical Study to Evaluate the Safety, Tolerability, and PK of HLX48 in Advanced/Metastatic Solid Tumors

Who this might be right for
Advanced/Metastatic Solid Tumors
Shanghai Henlius Biotech 72
Testing effectiveness (Phase 2)WithdrawnNCT02535078
What this trial is testing

Phase 1b/2 Study of the Combination of IMCgp100 With Durvalumab and/or Tremelimumab in Advanced Cutaneous Melanoma

Who this might be right for
Malignant Melanoma
Immunocore Ltd
Early research (Phase 1)Study completedNCT00274742
What this trial is testing

Safety Study of the Bispecific T-cell Engager Blinatumomab (MT103) in Patients With Relapsed NHL

Who this might be right for
Non-Hodgkin's Lymphoma, Relapsed
Amgen Research (Munich) GmbH 76
Testing effectiveness (Phase 2)Study completedNCT04224272
What this trial is testing

Phase 2a Study of ZW25 in Combination With Palbociclib Plus Fulvestrant

Who this might be right for
HER2+/HR+ Breast Cancer
Jazz Pharmaceuticals 51
Testing effectiveness (Phase 2)Active Not RecruitingNCT03933735
What this trial is testing

TNB-383B in Participants With Relapsed or Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
AbbVie 220
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