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Results for “Bispecific”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT03875209
What this trial is testing

10E8.4/iMab Bispecific Antibody in HIV-uninfected and HIV-infected Adults

Who this might be right for
HIV-1-infection
David Ho 54
Early research (Phase 1)Active Not RecruitingNCT04603287
What this trial is testing

SI-B001, an EGFR/HER3 Bispecific Antibody, in Locally Advanced or Metastatic Epithelial Tumors

Who this might be right for
Locally Advanced or Metastatic Epithelial Tumor
Sichuan Baili Pharmaceutical Co., Ltd. 60
Large-scale testing (Phase 3)Not Yet RecruitingNCT07739186
What this trial is testing

A Study Evaluating BL-B01D1 in Combination With a PD-1/VEGF Bispecific Antibody Versus Tislelizumab Plus Platinum-doublet Chemotherapy as First-line Treatment for Locally Advanced or Metastatic Non-squamous Non-small Cell Lung Cancer(PANKU-Lung06)

Who this might be right for
Non-squamous Non-small Cell Lung Cancer
Sichuan Baili Pharmaceutical Co., Ltd. 120
Testing effectiveness (Phase 2)Looking for participantsNCT06005493
What this trial is testing

Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Gastric CancerGastro-esophageal Junction CancerPancreatic Ductal Adenocarcinoma+1 more
AstraZeneca 392
Testing effectiveness (Phase 2)Active Not RecruitingNCT06508606
What this trial is testing

AK117 (Anti-CD47 mAb) Plus Cetuximab or AK104 (Anti-PD-1/CTLA-4 bsAb) as Second-Line Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma
West China Hospital 20
Testing effectiveness (Phase 2)Looking for participantsNCT06220487
What this trial is testing

A Single-arm, Open-label Study of Olverembatinib, CD3/CD19 Bispecific T-cell Engager, and Chidamide in Patients With Newly Diagnosed Ph+ALL

Who this might be right for
Acute Lymphoblastic LeukemiaPhiladelphia ChromosomePhiladelphia-Positive ALL+2 more
Nanfang Hospital, Southern Medical University 67
Early research (Phase 1)Study completedNCT03708328
What this trial is testing

A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid Tumors

Who this might be right for
Solid TumorsMetastatic MelanomaNon-small Cell Lung Cancer (NSCLC)+2 more
Hoffmann-La Roche 134
Early research (Phase 1)Looking for participantsNCT05828459
What this trial is testing

First-in-human Study of OT-A201 in Patients With Selected Hematological Malignancies and Solid Tumors

Who this might be right for
Hematological MalignancySolid Tumor
Onward Therapeutics 150
Testing effectiveness (Phase 2)UnknownNCT05781958
What this trial is testing

Cadonilimab Combined With Gem/Cis as First Line Therapy in Patients With Advanced ICC

Who this might be right for
Intrahepatic Cholangiocarcinoma
Shen Feng 64
Large-scale testing (Phase 3)Active Not RecruitingNCT05152147
What this trial is testing

Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers

Who this might be right for
Gastric NeoplasmsGastroesophageal AdenocarcinomaEsophageal Adenocarcinoma
Jazz Pharmaceuticals 920
Early research (Phase 1)Looking for participantsNCT05645276
What this trial is testing

AK129 in Patients With Advanced Malignant Tumors

Who this might be right for
Advanced Malignant Tumors(Stage IA-IB)
Akeso 182
Testing effectiveness (Phase 2)Active Not RecruitingNCT05229497
What this trial is testing

A Phase Ib/II Study of AK112 in Combination With AK117 in Advanced Malignant Tumors

Who this might be right for
Advanced Malignant Tumors
Akeso 154
Early research (Phase 1)Looking for participantsNCT06559189
What this trial is testing

CD19x22 Chimeric Antigen Receptor T-cell Therapy (CAR T) in Pediatric B-ALL

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
University of Colorado, Denver 53
Testing effectiveness (Phase 2)Looking for participantsNCT06817889
What this trial is testing

Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmAutoimmune DiseaseRespiratory Syncytial Virus Infection
Fred Hutchinson Cancer Center 60
Post-approval studies (Phase 4)Looking for participantsNCT07689578
What this trial is testing

Safety and Efficacy of the Bispecific T-Cell Engager (BiTE) in Kidney Transplant Recipients With Chronic Active Antibody-Mediated Rejection

Who this might be right for
Antibody Mediated Rejection After Kidney Transplantation
Turun Song 50
Early research (Phase 1)Ended earlyNCT05077423
What this trial is testing

Trial of CD33xCD3 BsAb in Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
AML, Childhood
Y-mAbs Therapeutics 3
Early research (Phase 1)Study completedNCT04440943
What this trial is testing

The PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies

Who this might be right for
Non-small Cell Lung CancerBreast CancerGastric Cancer+11 more
Celldex Therapeutics 27
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06746961
What this trial is testing

Efficacy and Safety of QL1706 Plus Lenvatinib As 2nd Line Theapy in Patients with Metastatic Esophageal Carcinoma After Disease Progression on ICIs Therapy

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)
The First Affiliated Hospital of Zhengzhou University 49
Testing effectiveness (Phase 2)UnknownNCT05425602
What this trial is testing

MAX-40279combined With KN046 in Patients With Advanced / Metastatic Solid Tumors

Who this might be right for
Advanced / Metastatic Solid Tumors
Maxinovel Pty., Ltd. 108
Early research (Phase 1)Looking for participantsNCT05137054
What this trial is testing

Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Participants With Multiple Myeloma That is Resistant to Current Standard of Care Treatments

Who this might be right for
Multiple Myeloma
Regeneron Pharmaceuticals 317
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