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Results for “Bispecific Antibodies”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT06762080
What this trial is testing

Intrathecal Combination of Programmed Death-1 (PD-1)/Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) Bispecific Antibody and Pemetrexed for Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis
Guangzhou Medical University 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT05247684
What this trial is testing

AK112 Neoadjuvant/Adjuvant Treatment for Resectable NSCLC

Who this might be right for
Resectable Non-small Cell Lung Cancer
Akeso 90
Early research (Phase 1)Looking for participantsNCT05403554
What this trial is testing

NI-1801 in Patients with Mesothelin Expressing Solid Cancers

Who this might be right for
Epithelial Ovarian CancerTriple Negative Breast CancerNon-squamous Non-small-cell Lung Cancer+2 more
Light Chain Bioscience - Novimmune SA 70
Early research (Phase 1)Study completedNCT03912441
What this trial is testing

First-In-Human Study to Evaluate Safety And Pharmacokinetics of Single Escalating Doses of BCD-147 (Bispecific Anti-HER2/HER2 Antibody) in Healthy Subjects

Who this might be right for
Healthy
Biocad 15
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07432594
What this trial is testing

Neoadjuvant Aitua (PD-1/CTLA-4 Bispecific) Plus Nab-Paclitaxel and Carboplatin for Advanced High-Grade Serous Ovarian Cancer

Who this might be right for
High-grade Serous Ovarian Cancer (HGSOC)Fallopian Tube CancersPrimary Peritoneal Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 82
Large-scale testing (Phase 3)Looking for participantsNCT06149286
What this trial is testing

A Trial to Find Out if Odronextamab Combined With Lenalidomide is Safe and Works Better Than Rituximab Combined With Lenalidomide in Adult Participants With Follicular Lymphoma and Marginal Zone Lymphoma

Who this might be right for
Relapsed/Refractory Follicular LymphomaRelapsed/Refractory Marginal Zone Lymphoma (R/R MZL)
Regeneron Pharmaceuticals 580
Early research (Phase 1)Ended earlyNCT04986865
What this trial is testing

A Study ATG-101 in Patients With Metastatic/Advanced Solid Tumors and Mature B-cell Non-Hodgkin Lymphomas

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorMature B-cell Non-Hodgkin Lymphoma
Antengene Biologics Limited 31
Early research (Phase 1)Study completedNCT03292783
What this trial is testing

This is a Study to Evaluate the Safety and Tolerability of the Study Drug ABL001, and to Determine the Maximum Tolerated Dose and/or Recommended Phase 2 Study Dose of ABL001

Who this might be right for
Advanced Solid Tumors
ABL Bio, Inc. 45
Early research (Phase 1)Active Not RecruitingNCT05464329
What this trial is testing

Mosunetuzumab in Combination With Platinum-Based Salvage Chemotherapy in Patients With Relapsed/Refractory Aggressive B Cell Lymphoma

Who this might be right for
Large B-cell LymphomaHigh-grade B-cell LymphomaTransformed B-Cell Lymphoma+1 more
Washington University School of Medicine 24
Early research (Phase 1)Looking for participantsNCT05685173
What this trial is testing

A Trial to Study if REGN5837 in Combination With Odronextamab is Safe for Adult Participants With Aggressive B-cell Non-Hodgkin Lymphomas

Who this might be right for
B-cell Non-Hodgkins Lymphoma (B-NHL)
Regeneron Pharmaceuticals 107
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07231250
What this trial is testing

Glofitamab Plus Polatuzumab Vedotin and Zuberitamab in Patients With Newly Diagnosed Diffuse Large B-cell Lymphoma

Who this might be right for
DLBCL - Diffuse Large B Cell LymphomaChemo-free TherapyBispecific Antibody
Li Zhiming 40
Testing effectiveness (Phase 2)Looking for participantsNCT07441889
What this trial is testing

HER2 FPBMC in Patients With Metastatic Breast and Prostate Cancer (AM006)

Who this might be right for
Breast CancerProstate Cancer
University of Virginia 23
Large-scale testing (Phase 3)Looking for participantsNCT06417008
What this trial is testing

HS-20117 Combined With Aumolertinib in Participants With Advanced Non-Squamous Non-Small Cell Lung Cancer

Who this might be right for
Non-Squamous Non-Small Cell Lung Cancer
Hansoh BioMedical R&D Company 1,080
Early research (Phase 1)WithdrawnNCT05381935
What this trial is testing

ES014 (Anti-CD39/TGF-β Bispecific Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumor
Elpiscience Biopharma, Ltd.
Large-scale testing (Phase 3)Looking for participantsNCT06006117
What this trial is testing

Mosunetuzumab-Lenalidomide Versus Investigator Choices in Patients With Relapsed or Refractory Marginal Zone Lymphoma

Who this might be right for
Marginal Zone Lymphoma
The Lymphoma Academic Research Organisation 260
Testing effectiveness (Phase 2)Looking for participantsNCT07106710
What this trial is testing

ASCT Combined With BCMA CAR-T and GPRC5D/CD3 BiTEs Maintenance for Transplant-Eligible Ultra-High-Risk Multiple Myeloma

Who this might be right for
Multiple Myeloma, Newly Diagnosed
Institute of Hematology & Blood Diseases Hospital, China 30
Testing effectiveness (Phase 2)Looking for participantsNCT07111520
What this trial is testing

A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)

Who this might be right for
Non-small Cell Lung Cancer
BioNTech SE 880
Not applicableLooking for participantsNCT07564219
What this trial is testing

BEAM-MM - β-Hydroxybutyrate-Enhanced Adaptive Immunity in Multiple Myeloma

Who this might be right for
Multiple Myeloma (MM)CAR T CellsBispecific Antibodies
Universitätsklinikum Hamburg-Eppendorf 45
Early research (Phase 1)UnknownNCT04887025
What this trial is testing

Exploratory Study of a Novel Oncolytic Vaccinia Virus RGV004 in the Treatment of Refractory/Relapsed B-cell Lymphoma

Who this might be right for
Relapsed or Refractory B-cell Lymphoma
Second Affiliated Hospital, Zhejiang University, School of Medicine 25
Testing effectiveness (Phase 2)Looking for participantsNCT06479239
What this trial is testing

Study of EGFRBi Armed Fresh PBMC in Metastatic or Unresectable Pancreatic Cancer

Who this might be right for
Pancreas CancerPancreatic Cancer
University of Virginia 23
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