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Results for “Bruton Tyrosine Kinase Inhibitor”

155 trials

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Showing 20 of 155 results

Early research (Phase 1)Not Yet RecruitingNCT07799597
What this trial is testing

Comparison of HBW-3220 Capsule Formulations and the Effect of Food in Healthy Participants

Who this might be right for
Healthy Volunteers
The Third Xiangya Hospital of Central South University 21
Testing effectiveness (Phase 2)Ended earlyNCT03093831
What this trial is testing

Phase II Study of Ibrutinib in Patients With Relapsed or Refractory Marginal Zone Lymphoma

Who this might be right for
Lymphoma, B-Cell, Marginal Zone
National Cancer Centre, Singapore 5
Testing effectiveness (Phase 2)UnknownNCT05200312
What this trial is testing

A Phase II Study of Zanubrutinib, Lenalidomide Plus R-CHOP as the First-line Treatment for Diffused Large B-cell Lymphoma

Who this might be right for
Non Hodgkin LymphomaDiffuse Large B Cell Lymphoma
The First Affiliated Hospital with Nanjing Medical University 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07819214
What this trial is testing

Epcoritamab as Consolidation Therapy for High-Risk Pts w/CLL on BTKI

Who this might be right for
CLLCLL (Chronic Lymphocytic Leukemia)Chronic Lymphocytic Leukemia (CLL)+1 more
University of California, Irvine 24
Testing effectiveness (Phase 2)Study completedNCT02077166
What this trial is testing

Ibrutinib in Combination With Lenalidomide and Rituximab in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Who this might be right for
Relapsed Diffuse Large B-Cell LymphomaRefractory Diffuse Large B-Cell Lymphoma
Pharmacyclics LLC. 138
Testing effectiveness (Phase 2)Study completedNCT03702231
What this trial is testing

Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL) and CLL Treated With Bruton's Tyrosine Kinase Inhibitor (BTK-I)

Who this might be right for
Safety and TolerabilityCompare SHINGRIX Vaccine Response RatesChronic Lymphocytic Leukemia (CLL)+1 more
National Heart, Lung, and Blood Institute (NHLBI) 116
Testing effectiveness (Phase 2)Active Not RecruitingNCT01589302
What this trial is testing

PCI-32765 (Ibrutinib) in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or B-cell Prolymphocytic Leukemia

Who this might be right for
Prolymphocytic LeukemiaRecurrent Small Lymphocytic LymphomaRefractory/Relapsed Chronic Lymphocytic Leukemia
Kami Maddocks, MD 154
Testing effectiveness (Phase 2)Study completedNCT01980654
What this trial is testing

Study of Ibrutinib in Combination With Rituximab in Previously Untreated Subjects With Follicular Lymphoma

Who this might be right for
Follicular LymphomaB-cell LymphomaNon-Hodgkin's Lymphoma
Pharmacyclics LLC. 80
Testing effectiveness (Phase 2)Ended earlyNCT02943473
What this trial is testing

Study on the Effect of Ibrutinib on High Risk Smoldering Multiple Myeloma Patients

Who this might be right for
High Risk Smoldering Multiple Myeloma
Icahn School of Medicine at Mount Sinai 9
Testing effectiveness (Phase 2)Study completedNCT02824029
What this trial is testing

Ibrutinib in Treating Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

Who this might be right for
Classical Hodgkin LymphomaRecurrent Hodgkin LymphomaRefractory Hodgkin Lymphoma
Barbara Ann Karmanos Cancer Institute 28
Testing effectiveness (Phase 2)Study completedNCT01478581
What this trial is testing

Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Relapsed or Relapsed and Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Pharmacyclics LLC. 92
Early research (Phase 1)Study completedNCT03703167
What this trial is testing

Ibrutinib With Rituximab and Lenalidomide for Patients With Recurrent/Refractory Primary or Secondary Central Nervous System Lymphoma (PCNSL/SCNSL)

Who this might be right for
Primary Central Nervous System Lymphoma (PCNSL)Secondary Central Nervous System Lymphoma (SCNSL)
Memorial Sloan Kettering Cancer Center 25
Testing effectiveness (Phase 2)Study completedNCT02362035
What this trial is testing

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies

Who this might be right for
Follicular Lymphoma (FL)CLLSmall Lymphocytic Lymphoma (SLL)+10 more
Acerta Pharma BV 161
Testing effectiveness (Phase 2)Study completedNCT02403271
What this trial is testing

A Multi-Center Study of Ibrutinib in Combination With MEDI4736 in Subjects With Relapsed or Refractory Solid Tumors

Who this might be right for
Non-Small Cell Lung CancerBreast CancerPancreatic Cancer
Pharmacyclics LLC. 124
Testing effectiveness (Phase 2)Study completedNCT03206970
What this trial is testing

Study to Evaluate Efficacy and Safety of BGB-3111 in Participants With Relapsed or Refractory Mantle Cell Lymphoma (MCL)

Who this might be right for
Refractory Mantle Cell LymphomaRelapsed Mantle Cell Lymphoma
BeiGene 86
Testing effectiveness (Phase 2)Active Not RecruitingNCT02514083
What this trial is testing

A Phase II Study Using Ibrutinib and Short-Course Fludarabine in Treatment-Naive CLL

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
National Heart, Lung, and Blood Institute (NHLBI) 29
Early research (Phase 1)UnknownNCT04173455
What this trial is testing

Study of the Safety, Tolerability and Pharmacokinetics of HZ-A-018 in Patients With B Cell Lymphoma

Who this might be right for
Lymphoma, B-Cell
First Affiliated Hospital of Zhejiang University 46
Testing effectiveness (Phase 2)Study completedNCT03685708
What this trial is testing

HEPLISAV-B Hepatitis B Vaccine in Chronic Lymphocytic Leukemia (CLL) and CLL Treated With Bruton's-Tyrosine Kinase Inhibitor (BTK-I)

Who this might be right for
HepatitisSafety and Tolerability
National Heart, Lung, and Blood Institute (NHLBI) 78
Testing effectiveness (Phase 2)Study completedNCT04062448
What this trial is testing

Ibrutinib in Combination With Rituximab, in Japanese Participants With Waldenstrom's Macroglobulinemia (WM)

Who this might be right for
Waldenstrom Macroglobulinemia
Janssen Pharmaceutical K.K. 16
Not applicableActive Not RecruitingNCT06125795
What this trial is testing

Assess Change in Functioning and Health Related Quality of Life in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Treatments in Routine Clinical Practice in Spain

Who this might be right for
Chronic Lymphocytic Leukemia
AbbVie 146
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