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Results for “Bruton Tyrosine Kinase Inhibitor”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT00849654
What this trial is testing

Study of the Safety and Tolerability of PCI-32765 in Patients With Recurrent B Cell Lymphoma

Who this might be right for
B-Cell LymphomaB-Cell Leukemia
Pharmacyclics LLC. 66
Early research (Phase 1)Study completedNCT04488016
What this trial is testing

Evaluate Relative Bioavailability, Proton Pump Inhibitor (PPI) (Rabeprazole) Effect, Food Effect and Particle Size Effect of New Acalabrutinib Tablet in Healthy Subjects

Who this might be right for
BioavailabilityB-cell Lymphoid Cancer
AstraZeneca 54
Testing effectiveness (Phase 2)Active Not RecruitingNCT02180724
What this trial is testing

An Open-label, Phase 2 Study of ACP-196 in Subjects With Waldenström Macroglobulinemia

Who this might be right for
Waldenström Macroglobulinemia (WM)
Acerta Pharma BV 107
Testing effectiveness (Phase 2)Ended earlyNCT02975349
What this trial is testing

Efficacy and Safety of M2951 in Participants With Relapsing Multiple Sclerosis

Who this might be right for
Relapsing-remitting Multiple Sclerosis
EMD Serono Research & Development Institute, Inc. 267
Testing effectiveness (Phase 2)Study completedNCT01520519
What this trial is testing

Phase 2 Study of the Combination of Bruton's Tyrosine Kinase Inhibitor PCI-32765 and Rituximab in High-Risk Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma Patients

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 40
Early research (Phase 1)Study completedNCT03943056
What this trial is testing

A Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of BIIB091, a Bruton's Tyrosine Kinase (BTK) Inhibitor, in Healthy Adult Participants

Who this might be right for
Healthy Volunteer
Biogen 64
Testing effectiveness (Phase 2)Study completedNCT01105247
What this trial is testing

Safety of PCI-32765 in Chronic Lymphocytic Leukemia

Who this might be right for
B-cell Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Pharmacyclics LLC. 133
Testing effectiveness (Phase 2)Ended earlyNCT03037645
What this trial is testing

Safety, PK, PD, and Antitumor Activity of Vecabrutinib (SNS-062) in B Lymphoid Cancers

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaLymphoplasmacytoid Lymphoma+5 more
Sunesis Pharmaceuticals 39
Large-scale testing (Phase 3)UnknownNCT03642236
What this trial is testing

Combination of BTK Inhibitor Overcomes Drug-resistance in Refractory/Relapsed FLT3 Mutant AML

Who this might be right for
FLT3-ITD MutationAcute Myeloid LeukemiaBrutons Tyrosine Kinase
Nanfang Hospital, Southern Medical University 122
Large-scale testing (Phase 3)Study completedNCT01974440
What this trial is testing

PCI-32765 (Ibrutinib) in Combination With Either Bendamustine and Rituximab or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Participants With Previously Treated Indolent Non-Hodgkin Lymphoma

Who this might be right for
Lymphoma
Janssen Research & Development, LLC 403
Large-scale testing (Phase 3)Study completedNCT02436668
What this trial is testing

Study of Ibrutinib vs Placebo, in Combination With Nab-paclitaxel and Gemcitabine, in the First Line Treatment of Patients With Metastatic Pancreatic Adenocarcinoma (RESOLVE)

Who this might be right for
Metastatic Pancreatic Adenocarcinoma
Pharmacyclics LLC. 430
Large-scale testing (Phase 3)Active Not RecruitingNCT05513001
What this trial is testing

An Extension Study of Long-term Efficacy, Safety and Tolerability of Remibrutinib in Chronic Spontaneous Urticaria Patients Who Completed Preceding Studies With Remibrutinib

Who this might be right for
Chronic Spontaneous Urticaria
Novartis Pharmaceuticals 696
Large-scale testing (Phase 3)Study completedNCT05048342
What this trial is testing

A Safety and Efficacy Study of Remibrutinib in the Treatment of CSU in Japanese Adults Inadequately Controlled by H1-antihistamines

Who this might be right for
Chronic Spontaneous Urticaria
Novartis Pharmaceuticals 71
Testing effectiveness (Phase 2)Study completedNCT01962792
What this trial is testing

Study of BTK Inhibitor, Ibrutinib in Combination With Carfilzomib in Subjects With Relapsed and Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Pharmacyclics LLC. 84
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07796373
What this trial is testing

Nemtabrutinib for Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Leukemia (SLL) Refractory to Covalent Bruton Tyrosine Kinase Inhibitor or Pirtobrutinib and Previously Treated With a BCL2 Inhibitor

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Leukemia
National Heart, Lung, and Blood Institute (NHLBI) 32
Testing effectiveness (Phase 2)Study completedNCT03206918
What this trial is testing

Efficacy and Safety of Zanubrutinib in Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Who this might be right for
Relapsed or Refractory Chronic Lymphocytic LeukemiaRelapsed or Refractory Small Lymphocytic Lymphoma
BeiGene 91
Testing effectiveness (Phase 2)Study completedNCT01744691
What this trial is testing

Phase 2 Study of Ibrutinib in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) With 17p Deletion

Who this might be right for
Chronic Lymphocytic Leukemia With 17p DeletionSmall Lymphocytic Lymphoma With 17p Deletion
Pharmacyclics LLC. 145
Testing effectiveness (Phase 2)Ended earlyNCT04047797
What this trial is testing

Ixazomib and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma

Who this might be right for
Recurrent Mantle Cell LymphomaRefractory Mantle Cell Lymphoma
M.D. Anderson Cancer Center 3
Large-scale testing (Phase 3)Study completedNCT04458051
What this trial is testing

Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS)

Who this might be right for
Primary Progressive Multiple Sclerosis
Sanofi 767
Testing effectiveness (Phase 2)UnknownNCT02747732
What this trial is testing

Study of Ibrutinib in Combination With Bendamustine and Rituximab for Patients With Relapsed/Refractory Aggressive BCL

Who this might be right for
Diffuse Large B Cell LymphomaPrimary Mediastinal (Thymic) Large B-cell LymphomaTransformed Indolent Lymphoma+2 more
Meirav Kedmi MD 72
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