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Results for “Brutons Tyrosine Kinase”

179 trials

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Showing 20 of 179 results

Testing effectiveness (Phase 2)Study completedNCT01962792
What this trial is testing

Study of BTK Inhibitor, Ibrutinib in Combination With Carfilzomib in Subjects With Relapsed and Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Pharmacyclics LLC. 84
Testing effectiveness (Phase 2)Study completedNCT02639910
What this trial is testing

Study to Evaluate Safety and Preliminary Efficacy of Tafasitamab With Idelalisib or Venetoclax in R/R CLL/SLL Patients Pretreated With BTKi

Who this might be right for
Leukemia, Lymphocytic, Chronic, B-CellChronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
MorphoSys AG 24
Not applicableLooking for participantsNCT07099443
What this trial is testing

Determinants of the Response to BTK Degraders (BTKd) in Double Refractory CLL

Who this might be right for
Chronic Lymphocytic LeukemiaRefractory Chronic Lymphocytic Leukemia
Nantes University Hospital 60
Large-scale testing (Phase 3)Study completedNCT04410991
What this trial is testing

Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (GEMINI 2)

Who this might be right for
Relapsing Multiple Sclerosis
Sanofi 899
Testing effectiveness (Phase 2)Looking for participantsNCT06520098
What this trial is testing

Phase II Study Of Bruton Tyrosine Kinase Inhibitor With Or Without Venetoclax In Veterans With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
VA Office of Research and Development 100
Early research (Phase 1)Looking for participantsNCT05780034
What this trial is testing

AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies

Who this might be right for
Relapsed/Refractory B-cell Malignancies
Accutar Biotechnology Inc 60
Testing effectiveness (Phase 2)UnknownNCT05200312
What this trial is testing

A Phase II Study of Zanubrutinib, Lenalidomide Plus R-CHOP as the First-line Treatment for Diffused Large B-cell Lymphoma

Who this might be right for
Non Hodgkin LymphomaDiffuse Large B Cell Lymphoma
The First Affiliated Hospital with Nanjing Medical University 36
Not applicableEnrolling By InvitationNCT06211413
What this trial is testing

Hypertension and Arrhythmias in CLL Patients Treated with BTK Inhibitors

Who this might be right for
Chronic Lymphocytic LeukemiaAtrial FibrillationHypertension+1 more
Abramson Cancer Center at Penn Medicine 50
Testing effectiveness (Phase 2)UnknownNCT04014205
What this trial is testing

Tyrosine Kinase Inhibitor Orelabrutinib (ICP-022) in Patients With r/r B-Cell Malignancies

Who this might be right for
Part 1：r/r B-cell MalignanciesPart 2：B-cell Malignancies
Beijing InnoCare Pharma Tech Co., Ltd. 81
Testing effectiveness (Phase 2)Study completedNCT02401048
What this trial is testing

A Multi-Center Study of Ibrutinib in Combination With MEDI4736 in Subjects With Relapsed or Refractory Lymphomas

Who this might be right for
Diffuse Large B-Cell LymphomaFollicular Lymphoma
Pharmacyclics LLC. 61
Early research (Phase 1)Study completedNCT01704963
What this trial is testing

Evaluate the Bruton's Tyrosine Kinase (Btk) Inhibitor PCI-32765 in Patients With Recurrent Mature B-Cell Neoplasms

Who this might be right for
Recurrent Mature B-cell Neoplasms
Janssen Pharmaceutical K.K. 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT02180724
What this trial is testing

An Open-label, Phase 2 Study of ACP-196 in Subjects With Waldenström Macroglobulinemia

Who this might be right for
Waldenström Macroglobulinemia (WM)
Acerta Pharma BV 107
Early research (Phase 1)Study completedNCT04768985
What this trial is testing

Study to Assess the Bioequivalence of Acalabrutinib Tablet and Acalabrutinib Capsule

Who this might be right for
Bioequivalence
AstraZeneca 66
Large-scale testing (Phase 3)Study completedNCT01776840
What this trial is testing

The Bruton's Tyrosine Kinase Inhibitor Ibrutinib Given in Combination With Bendamustine and Rituximab in Patients With Newly Diagnosed Mantle Cell Lymphoma

Who this might be right for
Mantle Cell Lymphoma
Janssen Research & Development, LLC 523
Early research (Phase 1)Study completedNCT05245396
What this trial is testing

Study Comparing Pharmacokinetics of Different Formulations of Evobrutinib in Healthy Participants

Who this might be right for
Healthy
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 58
Testing effectiveness (Phase 2)Study completedNCT03740529
What this trial is testing

Oral LOXO-305 in Patients With Previously Treated CLL/SLL or NHL

Who this might be right for
Chronic Lymphocytic LeukemiaWaldenstrom MacroglobulinemiaMantle Cell Lymphoma+3 more
Loxo Oncology, Inc. 803
Large-scale testing (Phase 3)Study completedNCT01974440
What this trial is testing

PCI-32765 (Ibrutinib) in Combination With Either Bendamustine and Rituximab or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Participants With Previously Treated Indolent Non-Hodgkin Lymphoma

Who this might be right for
Lymphoma
Janssen Research & Development, LLC 403
Testing effectiveness (Phase 2)Study completedNCT01744691
What this trial is testing

Phase 2 Study of Ibrutinib in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) With 17p Deletion

Who this might be right for
Chronic Lymphocytic Leukemia With 17p DeletionSmall Lymphocytic Lymphoma With 17p Deletion
Pharmacyclics LLC. 145
Not applicableLooking for participantsNCT06508684
What this trial is testing

Current Status of BTKi Treatment for CLL/SLL in China

Who this might be right for
CLL/SLL
The First Affiliated Hospital with Nanjing Medical University 1,000
Testing effectiveness (Phase 2)Study completedNCT02902965
What this trial is testing

Study of Ibrutinib in Combination With Bortezomib and Dexamethasone in Subjects With Relapsed/Relapsed and Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Pharmacyclics Switzerland GmbH 74
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