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Results for “Brutons Tyrosine Kinase”

187 trials

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Showing 20 of 187 results

Testing effectiveness (Phase 2)Ended earlyNCT02943473
What this trial is testing

Study on the Effect of Ibrutinib on High Risk Smoldering Multiple Myeloma Patients

Who this might be right for
High Risk Smoldering Multiple Myeloma
Icahn School of Medicine at Mount Sinai 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT04624906
What this trial is testing

Bendamustine, Rituximab and Acalabrutinib in Waldenstrom's Macroglobulinemia

Who this might be right for
Waldenstrom Macroglobulinemia
Sunnybrook Health Sciences Centre 63
Early research (Phase 1)Study completedNCT05190068
What this trial is testing

HMPL-760 in Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

Who this might be right for
B-Cell Non-Hodgkin's Lymphoma
Hutchmed 89
Early research (Phase 1)Ended earlyNCT02055924
What this trial is testing

Bruton's Tyrosine Kinase (BTK) Inhibition in B-cell Lymphomas

Who this might be right for
B-cell Lymphoma
The Lymphoma Academic Research Organisation 85
Testing effectiveness (Phase 2)Study completedNCT02169180
What this trial is testing

Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Relapsed or Refractory Mantle Cell Lymphoma

Who this might be right for
Lymphoma, Mantle-cell
Janssen Pharmaceutical K.K. 16
Not applicableUnknownNCT06508684
What this trial is testing

Current Status of BTKi Treatment for CLL/SLL in China

Who this might be right for
CLL/SLL
The First Affiliated Hospital with Nanjing Medical University 1,000
Large-scale testing (Phase 3)Study completedNCT04410991
What this trial is testing

Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (GEMINI 2)

Who this might be right for
Relapsing Multiple Sclerosis
Sanofi 899
Testing effectiveness (Phase 2)Ended earlyNCT04047797
What this trial is testing

Ixazomib and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma

Who this might be right for
Recurrent Mantle Cell LymphomaRefractory Mantle Cell Lymphoma
M.D. Anderson Cancer Center 3
Testing effectiveness (Phase 2)Ended earlyNCT02548962
What this trial is testing

Study of Ibrutinib in Combination With Pomalidomide and Dexamethasone in Subjects With Relapsed/Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Pharmacyclics LLC. 11
Testing effectiveness (Phase 2)Study completedNCT01599949
What this trial is testing

Evaluate the Efficacy and Safety of Ibrutinib, in Patients With Mantle Cell Lymphoma Who Progress After Bortezomib Therapy

Who this might be right for
Mantle Cell Lymphoma
Janssen Research & Development, LLC 120
Testing effectiveness (Phase 2)Active Not RecruitingNCT04546620
What this trial is testing

Acalabrutinib in Combination With R-CHOP for Previously Untreated Diffuse Large B-cell Lymphoma (DLBCL)

Who this might be right for
Diffuse Large B Cell Lymphoma
University Hospital Southampton NHS Foundation Trust 453
Testing effectiveness (Phase 2)Not Yet RecruitingNCT04913103
What this trial is testing

Study of PV in Combination With Bendamustine and Rituximab for Patients With R/R MCL

Who this might be right for
Lymphoma, Mantle-Cell
Czech Lymphoma Study Group 21
Testing effectiveness (Phase 2)Looking for participantsNCT06333262
What this trial is testing

Fixed Duration Pirtobrutinib and Obinutuzumab in Chronic Lymphocytic Leukemia

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Inhye Ahn 60
Not applicableLooking for participantsNCT05640102
What this trial is testing

Observational Study Evaluating the Efficacy and Safety of Zanubrutinib in Participants With Waldenström Macroglobulinemia

Who this might be right for
Waldenstrom Macroglobulinemia
BeiGene 111
Testing effectiveness (Phase 2)Ended earlyNCT02975349
What this trial is testing

Efficacy and Safety of M2951 in Participants With Relapsing Multiple Sclerosis

Who this might be right for
Relapsing-remitting Multiple Sclerosis
EMD Serono Research & Development Institute, Inc. 267
Testing effectiveness (Phase 2)Looking for participantsNCT03328078
What this trial is testing

CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

Who this might be right for
Relapsed Hematologic MalignancyRefractory Hematologic MalignancyRelapsed Primary Central Nervous System Lymphoma+1 more
Curis, Inc. 152
Testing effectiveness (Phase 2)Looking for participantsNCT06588478
What this trial is testing

A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Loxo Oncology, Inc. 249
Testing effectiveness (Phase 2)Study completedNCT05068440
What this trial is testing

Treatment of CD79B Mutant Relapsed/Refractory Diffuse Large B-Cell Lymphoma With Bruton Tyrosine Kinase Inhibitor Zanubrutinib

Who this might be right for
Relapsed Diffuse Large B-cell LymphomaRefractory Diffuse Large B-cell Lymphoma
BeiGene 65
Testing effectiveness (Phase 2)Active Not RecruitingNCT05249959
What this trial is testing

Consolidation With Loncastuximab Tesirine After a Short Course of Immunochemotherapy in BTKi-treated (or Intolerant) Relapsed/Refractory Mantle Cell Lymphoma Patients.

Who this might be right for
Relapsed Mantle Cell LymphomaRefractory Mantle Cell Lymphoma
Fondazione Italiana Linfomi - ETS 49
Early research (Phase 1)Looking for participantsNCT05990465
What this trial is testing

LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies

Who this might be right for
Non Hodgkin LymphomaDiffuse Large B Cell LymphomaFollicular Lymphoma+3 more
Medical College of Wisconsin 12
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