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Results for “CAR-NK”

170 trials

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Showing 20 of 170 results

Testing effectiveness (Phase 2)Looking for participantsNCT07410494
What this trial is testing

Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors

Who this might be right for
CancerBreast CancerNon-Small Cell Lung Cancer (NSCLC)+10 more
Essen Biotech 85
Testing effectiveness (Phase 2)Looking for participantsNCT07589530
What this trial is testing

Phase 1/2 Study of EB-NK-301 (Allogeneic TROP2-CAR NK Cells) in Advanced TROP2-Expressing Solid Tumors

Who this might be right for
Advanced Solid TumorsMetastatic Solid TumorsTROP2-Expressing Solid Tumors
Beijing Biotech 60
Very early researchLooking for participantsNCT07298239
What this trial is testing

An Exploratory Clinical Study Evaluating the Safety and Efficacy of Allogeneic CAR-NK Cell Therapy for Metastatic Castration-resistant Prostate Cancer (mCRPC)

Who this might be right for
Prostate Cancer Castration-resistant Prostate Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 15
Early research (Phase 1)Looking for participantsNCT05995028
What this trial is testing

Universal 4SCAR7U Targeting CD7-positive Malignancies

Who this might be right for
T-cell Acute Lymphoblastic LeukemiaT-cell Acute Lymphoblastic LymphomaAcute Myeloid Leukemia+1 more
Shenzhen Geno-Immune Medical Institute 30
Early research (Phase 1)UnknownNCT03415100
What this trial is testing

Pilot Study of NKG2D-Ligand Targeted CAR-NK Cells in Patients With Metastatic Solid Tumours

Who this might be right for
Solid Tumours
The Third Affiliated Hospital of Guangzhou Medical University 30
Early research (Phase 1)Active Not RecruitingNCT04623944
What this trial is testing

NKX101, Intravenous Allogeneic CAR NK Cells, in Adults With AML or MDS

Who this might be right for
Relapsed/Refractory AMLAML, AdultMDS+1 more
Nkarta, Inc. 61
Testing effectiveness (Phase 2)Looking for participantsNCT07627711
What this trial is testing

Dual-Target CAR-NK Cells Targeting Mesothelin (MSLN) and MUC1 in Advanced Pancreatic Ductal Adenocarcinoma

Who this might be right for
Pancreatic Ductal Adenocarcinoma (PDAC)Unresectable Locally AdvancedMetastatic Disease
Beijing Biotech 42
Very early researchLooking for participantsNCT06045091
What this trial is testing

To Evaluate the Safety and Efficacy of Human BCMA Targeted CAR-NK Cells Injection for Subjects With R/R MM or PCL

Who this might be right for
Multiple MyelomaPlasma Cell Leukemia
Hrain Biotechnology Co., Ltd. 18
Testing effectiveness (Phase 2)UnknownNCT02134262
What this trial is testing

Gene Therapy for B-Cell Non-Hodgkin Lymphoma Using CD19 CAR Gene Transduced T Lymphocytes

Who this might be right for
Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Jichi Medical University 18
Testing effectiveness (Phase 2)Looking for participantsNCT07480213
What this trial is testing

Adaptive Phase 1/2 Study of Dual-Target CAR-NK Cells in Relapsed/Refractory Small Cell Lung Cancer (SCLC)

Who this might be right for
Small Cell Lung Cancer (SCLC)Relapsed/Refractory SCLCSCLC, Extensive Stage
Beijing Biotech 60
Very early researchNot Yet RecruitingNCT07117175
What this trial is testing

A Clinical Study to Evaluate the Safety and Efficacy of Anti-human CD 7 CAR-NK Cell Injection in Subjects With Relapsed and Refractory CD7-positive Hematological Malignancy

Who this might be right for
ImmunologyHematologic MalignanciesCAR-NK
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 18
Early research (Phase 1)Study completedNCT05182073
What this trial is testing

FT576 in Subjects With Multiple Myeloma

Who this might be right for
Multiple MyelomaMyeloma
Fate Therapeutics 31
Very early researchNot Yet RecruitingNCT07243366
What this trial is testing

Allogeneic CD19-CAR-NK Cells in Patients With Refractory Myasthenia Gravis

Who this might be right for
Refractory Myasthenia Gravis
Guangdong ProCapZoom Biosciences Co., Ltd. 15
Testing effectiveness (Phase 2)Looking for participantsNCT07627698
What this trial is testing

Dual-Target CSPG4/GD2 CAR-NK Cells for Advanced Melanoma

Who this might be right for
Unresectable MelanomaMetastatic Cutaneous MelanomaMetastatic Uveal Melanoma
Beijing Biotech 36
Early research (Phase 1)Looking for participantsNCT07492628
What this trial is testing

Dual-Target Nectin-4/HER2 CAR-NK Cells in Advanced Urothelial Carcinoma

Who this might be right for
Bladder CancerUrothelial CarcinomaMetastatic Urothelial Carcinoma+2 more
Beijing Biotech 42
Early research (Phase 1)Active Not RecruitingNCT06325748
What this trial is testing

SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS

Who this might be right for
AML/MDSCD33 Expressing Hematological MalignanciesFLT3 Expressing Hematological Malignancies
Senti Biosciences 21
Very early researchActive Not RecruitingNCT06596057
What this trial is testing

Safety and Efficacy of CD19 CAR-T/CAR-NK Cells

Who this might be right for
Safety and Efficacy
The Second Hospital of Shandong University 10
Early research (Phase 1)Ended earlyNCT03203369
What this trial is testing

Study to Evaluate the Safety and Clinical Activity of UCART123 in Patients With BPDCN

Who this might be right for
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
Cellectis S.A. 1
Testing effectiveness (Phase 2)UnknownNCT04033302
What this trial is testing

Multi-CAR T Cell Therapy Targeting CD7-positive Malignancies

Who this might be right for
T-cell Acute Lymphoblastic LeukemiaT-cell Acute Lymphoblastic LymphomaAcute Myeloid Leukemia+1 more
Shenzhen Geno-Immune Medical Institute 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07164469
What this trial is testing

Phase 2 Trial of CD70.CAR NK Cells for Patients With Primary Refractory or Early Relapsed Diffuse Large B-Cell Lymphoma and Hodgkin Lymphoma

Who this might be right for
Large B-cell LymphomaHodgkin Lymphoma
M.D. Anderson Cancer Center 100
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