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Results for “CD19+ Acute Leukemia”

339 trials

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Showing 20 of 339 results

Early research (Phase 1)Looking for participantsNCT07239323
What this trial is testing

In VIVO CAR-T Therapy for Relapsed/Refractory Hematological Malignancies

Who this might be right for
B-Acute Lymphoblastic LeukemiaB Cell Non-Hodgkin's LymphomaMultiple Myeloma
Chongqing Precision Biotech Co., Ltd 24
Testing effectiveness (Phase 2)Study completedNCT03097770
What this trial is testing

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD20

Who this might be right for
Hematopoietic/Lymphoid CancerAdult Acute Lymphoblastic Leukemia in RemissionB-cell Adult Acute Lymphoblastic Leukemia+20 more
Chinese PLA General Hospital 100
Early research (Phase 1)Looking for participantsNCT07573111
What this trial is testing

Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell Transplantation

Who this might be right for
Acute LeukemiaMyelodysplastic Syndrome
Laguna Biotherapeutics, Inc. 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT03573700
What this trial is testing

Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia, in RelapseAcute Lymphoblastic Leukemia, Refractory
St. Jude Children's Research Hospital 24
Not applicableStudy completedNCT05440409
What this trial is testing

CAR-Multicenter Analysis (CAR-MA): Retrospective Study to Characterize CAR T-cell Outcomes and Related Toxicities in Children and Young Adults With B-ALL

Who this might be right for
Leukemia, Acute LymphoblasticLymphoblastic Leukemia, Acute, Childhood
National Cancer Institute (NCI) 57
Early research (Phase 1)Active Not RecruitingNCT00840853
What this trial is testing

Multi-virus CTLs Expressing CD19 Chimeric Receptors, CD19 Positive Malignancies Post SCT, MULTIPRAT

Who this might be right for
Acute Lymphoblastic Leukemia (ALL)Chronic Lymphocytic Leukemia (CLL)Non Hodgkin's Lymphoma
Baylor College of Medicine 68
Large-scale testing (Phase 3)Looking for participantsNCT07570173
What this trial is testing

A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Merck Sharp & Dohme LLC 340
Not applicableNot Yet RecruitingNCT07245251
What this trial is testing

To Evaluate the Safety, Tolerability, and Preliminary Antitumor Activity of STR-P004

Who this might be right for
Acute Lymphobkastic Leukemia
Starna Therapeutics 11
Very early researchLooking for participantsNCT06696833
What this trial is testing

Allogeneic CD19-targeted CAR-γδT Cell Infusion Therapy in Relapsed/Refractory B Cell Acute Lymphoblastic Leukemia

Who this might be right for
B-Cell Acute Lymphoblastic Leukemia, Adult
The First Affiliated Hospital of Soochow University 18
Early research (Phase 1)Ended earlyNCT01551043
What this trial is testing

Allo CART-19 Protocol

Who this might be right for
Acute Lymphocytic Leukemia
University of Pennsylvania 2
Testing effectiveness (Phase 2)Looking for participantsNCT05667506
What this trial is testing

CNCT19 Treatment in Children and Adolescent r/r ALL Patients(Pediatric)

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Juventas Cell Therapy Ltd. 47
Early research (Phase 1)Looking for participantsNCT06326008
What this trial is testing

Safety, Tolerability, and Pharmacokinetics of Donor-derived CD19 CAR Therapy Bridged Allo-HSCT and Sequential Donor-derived CD22 CAR Therapy for r/r B-ALL: a Clinical Trial

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaAcute Lymphoblastic Leukemia, in Relapse
Beijing GoBroad Hospital 48
Early research (Phase 1)Looking for participantsNCT06080191
What this trial is testing

Allogeneic Second-generation CD19-CAR T Cells for Pediatric Relapsed/Refractory B-ALL

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
Bambino Gesù Hospital and Research Institute 24
Early research (Phase 1)Looking for participantsNCT06227026
What this trial is testing

Pilot Study of Anti-CD19 Chimeric Antigen Receptor T Cells (CAR-T Cells) for the Treatment of Relapsed/Refractory CD19+ Malignancies

Who this might be right for
Acute Lymphoblastic LeukemiaDiffuse Large B Cell Lymphoma
University of Utah 10
Early research (Phase 1)Looking for participantsNCT07108868
What this trial is testing

A Phase I Dose Finding Study of MB-CART2219.1

Who this might be right for
LymphomaCLLAcute Lymphoblastic Leukemia, Pediatric
University Hospital Tuebingen 36
Early research (Phase 1)Active Not RecruitingNCT02935257
What this trial is testing

Immunotherapy for High Risk/Relapsed CD19+ Acute Lymphoblastic Leukaemia, B-cell Non-Hodgkin's Lymphoma (B-NHL) and Chronic Lymphocytic Leukaemia (CLL)/ Small Lymphocytic Lymphoma (SLL) Using CAR T-cells to Target CD19

Who this might be right for
Leukemia, Lymphoblastic, Acute, Lymphoma
University College, London 72
Testing effectiveness (Phase 2)Looking for participantsNCT06081478
What this trial is testing

CD19/CD22 Bispecific CAR-T Cell Therapy for Relapsed/Refractory B-cell Lymphoma or Acute Lymphoblastic Leukemia

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaB-cell LymphomaDiffuse Large B Cell Lymphoma
Beijing Tongren Hospital 100
Early research (Phase 1)Not Yet RecruitingNCT07539610
What this trial is testing

Evaluation of the Safety and Efficacy of Sup19 CAR-T Cells in Patients With Previously Failed CD19-Targeted Therapy or CD19-Weakly Expressed Hematologic Tumors

Who this might be right for
B-Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia/Lymphoma
Institute of Hematology & Blood Diseases Hospital, China 9
Large-scale testing (Phase 3)Looking for participantsNCT07441291
What this trial is testing

CD19 CAR-T vs DLI for Post-HSCT MRD in Ph- ALL: A RCT

Who this might be right for
B ALLAllogenetic Hematopoietic Stem Cell TransplantationMRD-positive
Peking University People's Hospital 70
Testing effectiveness (Phase 2)WithdrawnNCT05936229
What this trial is testing

Interferon-Beta-1a (FP-1201) to Prevent Toxicities After CD19-Directed CAR T-Cell Therapy

Who this might be right for
Recurrent B Acute Lymphoblastic LeukemiaRecurrent B-Cell Non-Hodgkin LymphomaRefractory B Acute Lymphoblastic Leukemia+3 more
Fred Hutchinson Cancer Center
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