Testing effectiveness (Phase 2)Study completedNCT03861871What this trial is testingFenfluramine in CDKL5 Deficiency Disorder (CDD)Who this might be right forCDD NYU Langone Health 7
Testing effectiveness (Phase 2)Study completedNCT03694275What this trial is testingA Multicenter, Open-label, Pilot Study of Soticlestat (TAK-935/OV935) in Participants With 15Q Duplication Syndrome (Dup 15q) or Cyclin-Dependent Kinase-Like 5 (CDKL5) Deficiency Disorder (ARCADE STUDY)Who this might be right for15q Duplication SyndromeCDKL5 Deficiency Disease Takeda 20
Not applicableLooking for participantsNCT06448663What this trial is testingTargeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD)Who this might be right forCDKL5 University of Milan 20
Early research (Phase 1)Active Not RecruitingNCT03875287What this trial is testingDose-Escalation Study of E7727, an Oral Cytidine Deaminase Inhibitor With Oral Decitabine in Subjects With Solid TumorsWho this might be right forSolid Tumor Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 35
Large-scale testing (Phase 3)UnknownNCT02336386What this trial is testingCDD Plus Bortezomib or CDDin Relapsed or Refractory Multiple Myeloma With Extramedullary PlasmacytomaWho this might be right forExtramedullary Plasmacytoma Beijing Chao Yang Hospital 100
Not applicableLooking for participantsNCT04486768What this trial is testingInternational CDKL5 RegistryWho this might be right forCDKL5 Deficiency Disorder (CDD) University of Pennsylvania 500
Large-scale testing (Phase 3)Study completedNCT03572933What this trial is testingStudy of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency DisorderWho this might be right forCDKL5 Deficiency Disorder Marinus Pharmaceuticals 101
Not applicableActive Not RecruitingNCT05373719What this trial is testingObservational Study in Patients With Cyclin-dependent Kinase-like 5 Deficiency DisorderWho this might be right forCyclin-Dependent Kinase-Like 5 Deficiency Disorder Loulou Foundation 112
Not applicableStudy completedNCT03816410What this trial is testingNatriuretic Peptides After Left Atrial Appendage AmputationWho this might be right forAtrial Fibrillation University of Giessen 21
Testing effectiveness (Phase 2)Study completedNCT01416662What this trial is testingGemcitabine Hydrochloride in Treating Patients With Pancreatic Cancer That Has Been Removed by SurgeryWho this might be right forPancreatic Cancer Federation Francophone de Cancerologie Digestive 120
Large-scale testing (Phase 3)Not Yet RecruitingNCT05249556What this trial is testingDouble-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years OldWho this might be right forCDKL5 Deficiency Disorder Immedica Pharma AB 20
Not applicableLooking for participantsNCT05558371What this trial is testingInternational CDKL5 Clinical Research NetworkWho this might be right forCDKL5CDKL5 Deficiency DisorderCDD University of Colorado, Denver 1,000
Testing effectiveness (Phase 2)Study completedNCT02103478What this trial is testingPharmacokinetic Guided Dose Escalation and Dose Confirmation With Oral Decitabine and Oral Cytidine Deaminase Inhibitor (CDAi) in Patients With Myelodysplastic Syndromes (MDS)Who this might be right forMyelodysplastic SyndromeMDS Astex Pharmaceuticals, Inc. 130
Early research (Phase 1)Ended earlyNCT04155580What this trial is testingASTX660 as a Single Agent and in Combination With ASTX727 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML)Who this might be right forAcute Myeloid Leukemia Astex Pharmaceuticals, Inc. 68
Not applicableUnknownNCT02489929What this trial is testingEvaluation of Cytidine Deaminase for Patient Suffering of a Myelodysplastic Syndrom or an AML Treated by AzacytidineWho this might be right forMyeloid LeukemiaMyelodysplastic Syndromes Assistance Publique Hopitaux De Marseille 35
Testing effectiveness (Phase 2)Ended earlyNCT03233724What this trial is testingOral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal CarcinomasWho this might be right forCarcinoma, Non-Small-Cell LungLung CancerNon-Small Cell Lung Cancer+2 more National Cancer Institute (NCI) 9