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Results for “CDD”

17 trials

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Showing 17 of 17 results

Early research (Phase 1)Ended earlyNCT04155580
What this trial is testing

ASTX660 as a Single Agent and in Combination With ASTX727 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Astex Pharmaceuticals, Inc. 68
Large-scale testing (Phase 3)UnknownNCT02336386
What this trial is testing

CDD Plus Bortezomib or CDDin Relapsed or Refractory Multiple Myeloma With Extramedullary Plasmacytoma

Who this might be right for
Extramedullary Plasmacytoma
Beijing Chao Yang Hospital 100
Large-scale testing (Phase 3)Not Yet RecruitingNCT05249556
What this trial is testing

Double-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years Old

Who this might be right for
CDKL5 Deficiency Disorder
Immedica Pharma AB 20
Not applicableLooking for participantsNCT05558371
What this trial is testing

International CDKL5 Clinical Research Network

Who this might be right for
CDKL5CDKL5 Deficiency DisorderCDD
University of Colorado, Denver 1,000
Not applicableUnknownNCT02489929
What this trial is testing

Evaluation of Cytidine Deaminase for Patient Suffering of a Myelodysplastic Syndrom or an AML Treated by Azacytidine

Who this might be right for
Myeloid LeukemiaMyelodysplastic Syndromes
Assistance Publique Hopitaux De Marseille 35
Testing effectiveness (Phase 2)Study completedNCT01416662
What this trial is testing

Gemcitabine Hydrochloride in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery

Who this might be right for
Pancreatic Cancer
Federation Francophone de Cancerologie Digestive 120
Not applicableActive Not RecruitingNCT05373719
What this trial is testing

Observational Study in Patients With Cyclin-dependent Kinase-like 5 Deficiency Disorder

Who this might be right for
Cyclin-Dependent Kinase-Like 5 Deficiency Disorder
Loulou Foundation 112
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07418931
What this trial is testing

Open-label Phase II Study of Cemiplimab Plus Chemotherapy, Selected on the Basis of Baseline Cytidine Deaminase Activity, in Advanced Squamous Non-small Cell Lung Cancer

Who this might be right for
Advanced Squamous Non-Small Cell Lung Cancer
Gruppo Oncologico Italiano di Ricerca Clinica 108
Testing effectiveness (Phase 2)Ended earlyNCT03233724
What this trial is testing

Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomas

Who this might be right for
Carcinoma, Non-Small-Cell LungLung CancerNon-Small Cell Lung Cancer+2 more
National Cancer Institute (NCI) 9
Not applicableStudy completedNCT03816410
What this trial is testing

Natriuretic Peptides After Left Atrial Appendage Amputation

Who this might be right for
Atrial Fibrillation
University of Giessen 21
Testing effectiveness (Phase 2)Study completedNCT03694275
What this trial is testing

A Multicenter, Open-label, Pilot Study of Soticlestat (TAK-935/OV935) in Participants With 15Q Duplication Syndrome (Dup 15q) or Cyclin-Dependent Kinase-Like 5 (CDKL5) Deficiency Disorder (ARCADE STUDY)

Who this might be right for
15q Duplication SyndromeCDKL5 Deficiency Disease
Takeda 20
Testing effectiveness (Phase 2)Study completedNCT02103478
What this trial is testing

Pharmacokinetic Guided Dose Escalation and Dose Confirmation With Oral Decitabine and Oral Cytidine Deaminase Inhibitor (CDAi) in Patients With Myelodysplastic Syndromes (MDS)

Who this might be right for
Myelodysplastic SyndromeMDS
Astex Pharmaceuticals, Inc. 130
Not applicableLooking for participantsNCT06448663
What this trial is testing

Targeting the Gut to Improve Seizure Control in CDKL5 Deficiency Disorder (CDD)

Who this might be right for
CDKL5
University of Milan 20
Not applicableLooking for participantsNCT04486768
What this trial is testing

International CDKL5 Registry

Who this might be right for
CDKL5 Deficiency Disorder (CDD)
University of Pennsylvania 500
Early research (Phase 1)Active Not RecruitingNCT03875287
What this trial is testing

Dose-Escalation Study of E7727, an Oral Cytidine Deaminase Inhibitor With Oral Decitabine in Subjects With Solid Tumors

Who this might be right for
Solid Tumor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 35
Testing effectiveness (Phase 2)Study completedNCT03861871
What this trial is testing

Fenfluramine in CDKL5 Deficiency Disorder (CDD)

Who this might be right for
CDD
NYU Langone Health 7
Large-scale testing (Phase 3)Study completedNCT03572933
What this trial is testing

Study of Adjunctive Ganaxolone Treatment in Children and Young Adults With CDKL5 Deficiency Disorder

Who this might be right for
CDKL5 Deficiency Disorder
Marinus Pharmaceuticals 101