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Results for “CDKN2A”

52 trials

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Showing 20 of 52 results

Not applicableUnknownNCT00343213
What this trial is testing

Diagnostic and Prognostic Value of p16INK4a Expression in Low Grade Squamous Intraepithelial Lesions of the Cervix.

Who this might be right for
Cervical Intraepithelial Neoplasia Grade 1 (CIN 1)
University Hospital, Strasbourg, France 300
Testing effectiveness (Phase 2)Active Not RecruitingNCT03389477
What this trial is testing

Los Tres Paso: Neoadjuvant Palbociclib Monotherapy, Concurrent Chemoradiation Therapy, Adjuvant Palbociclib Monotherapy in Patients With p16INK4a Negative, HPV-Unrelated Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Washington University School of Medicine 26
Early research (Phase 1)Study completedNCT07160738
What this trial is testing

Learn About How the Study Medicines Called Itraconazole and Probenecid Change How the Body Processes PF-07220060

Who this might be right for
Healthy Adults
Pfizer 25
Large-scale testing (Phase 3)Looking for participantsNCT07063745
What this trial is testing

Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

Who this might be right for
Metastatic Non-small Cell Lung Cancer With MTAP Deletion
Bristol-Myers Squibb 590
Not applicableUnknownNCT03524677
What this trial is testing

Mutation of K-RAS, CDKN2A, SMAD4 and TP53 in Pancreatic Cancer: Role of Liquid Biopsy in Preoperative Diagnosis

Who this might be right for
Pancreatic Cancer
University of Roma La Sapienza 50
Large-scale testing (Phase 3)Looking for participantsNCT04966481
What this trial is testing

Palbociclib and Cetuximab Versus Cetuximab Monotherapy for Patients With CDKN2A-altered, HPV-unrelated Head and Neck Squamous Cell Carcinoma Who Experienced Disease Progression on a PD-1/L1 Inhibitor

Who this might be right for
HPV-unrelated Head and Neck Squamous Cell Carcinoma
Washington University School of Medicine 81
Not applicableLooking for participantsNCT06789653
What this trial is testing

A Novel Approach Utilizing Organ Specific Age Proteomics

Who this might be right for
Breast Cancer
UNC Lineberger Comprehensive Cancer Center 80
Early research (Phase 1)Looking for participantsNCT07077434
What this trial is testing

Assess Safety, Tolerability and Drug Levels of Navlimetostat (BMS-986504) in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Bristol-Myers Squibb 32
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07492680
What this trial is testing

BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

Who this might be right for
Solid Tumors
Bristol-Myers Squibb 260
Early research (Phase 1)Looking for participantsNCT05508906
What this trial is testing

Phase 1b Study of OP-1250 (Palazestrant) in Combination With Ribociclib, Alpelisib, Everolimus, or Atirmociclib in ER+, HER2- Breast Cancer

Who this might be right for
Metastatic Breast CancerER-positive Breast CancerHER2-negative Breast Cancer+2 more
Olema Pharmaceuticals, Inc. 190
Not applicableStudy completedNCT00003933
What this trial is testing

Diagnostic Study of Gene Alterations in Children Who Have Been Treated for Relapsed Acute Lymphocytic Leukemia

Who this might be right for
Leukemia
Children's Oncology Group
Testing effectiveness (Phase 2)Ended earlyNCT05935748
What this trial is testing

Ph2 Study NKT2152 With Palbociclib & Sasanlimab in Subjects With Advanced Clear Cell Renal Cell Carcinoma (ccRcc)

Who this might be right for
ccRCCClear Cell Renal Cell CarcinomaKidney Cancer+18 more
NiKang Therapeutics, Inc. 18
Very early researchEnded earlyNCT04074785
What this trial is testing

Abemaciclib w/Bevacizumab in Recurrent GBM Pts w/Loss of CDKN2A/B or Gain or Amplification of CDK4/6

Who this might be right for
GBMGlioblastomaBrain Tumor+1 more
University of Texas Southwestern Medical Center 10
Early research (Phase 1)Study completedNCT02540876
What this trial is testing

Ilorasertib in Treating Patients With CDKN2A-deficient Advanced or Metastatic Solid Cancers That Cannot Be Removed by Surgery

Who this might be right for
Metastatic Malignant NeoplasmSolid NeoplasmUnresectable Malignant Neoplasm
University of Chicago 12
Testing effectiveness (Phase 2)UnknownNCT03096912
What this trial is testing

A Study Assessing Efficacy & Safety of Ribociclib in Patients With Advanced Well/Dedifferentiated Liposarcoma

Who this might be right for
Liposarcomas, DedifferentiatedLiposarcoma - Well DifferentiatedLiposarcoma; Mixed Type+1 more
Assaf-Harofeh Medical Center 30
Early research (Phase 1)Looking for participantsNCT06113809
What this trial is testing

Palbociclib and Pembrolizumab in Sarcoma

Who this might be right for
Sarcoma
John Rieth 8
Early research (Phase 1)Looking for participantsNCT06120283
What this trial is testing

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorAdvanced Breast CancerMetastatic Breast Cancer+6 more
BeOne Medicines 399
Early research (Phase 1)Study completedNCT06253195
What this trial is testing

BGB-43395 Alone or as Part of Combination Therapies in Chinese Participants With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorHormone-receptor-positive Breast Cancer+4 more
BeOne Medicines 33
Testing effectiveness (Phase 2)WithdrawnNCT06090318
What this trial is testing

Milademetan in Combination With Atezolizumab in Patients With Advanced Solid Tumors With CDKN2A Loss

Who this might be right for
Advanced Solid TumorCDKN2ANSCLC+7 more
Rain Oncology Inc
Not applicableStudy completedNCT01138345
What this trial is testing

Biomarkers in Blood Samples From Older Breast Cancer Survivors

Who this might be right for
Breast Cancer
UNC Lineberger Comprehensive Cancer Center 246
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