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Results for “CEACAM5”

64 trials

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Showing 20 of 64 results

Early research (Phase 1)Study completedNCT00004604
What this trial is testing

Biological Therapy in Treating Patients With Metastatic Cancer

Who this might be right for
Breast CancerColorectal CancerExtrahepatic Bile Duct Cancer+9 more
Duke University 24
Early research (Phase 1)Study completedNCT02650713
What this trial is testing

The Safety, Pharmacokinetics, and Therapeutic Activity of RO6958688 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Carcinoembryonic Antigen (CEA)-Positive Solid Tumors

Who this might be right for
Solid Tumors
Hoffmann-La Roche 228
Testing effectiveness (Phase 2)Ended earlyNCT05245071
What this trial is testing

Tusamitamab Ravtansine in NSQ NSCLC Participants With Negative or Moderate CEACAM5 Expression Tumors and High Circulating CEA

Who this might be right for
Non-squamous Non-small Cell Lung Cancer
Sanofi 22
Early research (Phase 1)Active Not RecruitingNCT06806046
What this trial is testing

Anti-CEACAM5 ADC Precemtabart Tocentecan (M9140) in Chinese Participants With Solid Tumors

Who this might be right for
Solid TumorsColorectal Cancer
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 12
Early research (Phase 1)Study completedNCT01284231
What this trial is testing

Evaluate the Safety and Tolerability of MEDI-565 in Adults With Gastrointestinal Adenocarcinomas

Who this might be right for
Gastrointestinal Adenocarcinomas
MedImmune LLC 78
Not applicableUnknownNCT01052818
What this trial is testing

Therapeutic and Prognostic Impact of Circulating Tumor Cells in Peripheral Blood in Patients With Non Small-cell Lung Cancer

Who this might be right for
Circulating Tumor Cells
National Institute of Cancerología 200
Early research (Phase 1)Looking for participantsNCT06043466
What this trial is testing

A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors

Who this might be right for
Colorectal CancerEsophagus CancerGastric Cancer+4 more
Chongqing Precision Biotech Co., Ltd 30
Early research (Phase 1)Not Yet RecruitingNCT07686445
What this trial is testing

AN4035 in Advanced Cancers With RAS Mutations and High CEACAM5 Expression

Who this might be right for
Solid Tumor (Phase I)RAS MutationCEACAM5
Adlai Nortye Biopharma Co., Ltd. 228
Not applicableStudy completedNCT01494077
What this trial is testing

Accuracy of Dilution of EUS-FNA Pancreatic Cyst Fluid for Carcinoembryonic Antigen (CEA) Measurement

Who this might be right for
Pancreatic Cyst
University of California, Irvine 32
Post-approval studies (Phase 4)Not Yet RecruitingNCT06665334
What this trial is testing

To Explore the Effect of Huaier Granule on the Negative Conversion Rate After the CEA Level Increases Again After Colorectal Cancer Surgery

Who this might be right for
Colorectal Cancer
Fudan University 134
Early research (Phase 1)Study completedNCT02850536
What this trial is testing

CAR-T Hepatic Artery Infusions or Pancreatic Venous Infusions for CEA-Expressing Liver Metastases or Pancreas Cancer

Who this might be right for
Liver Metastases
Roger Williams Medical Center 5
Not applicableUnknownNCT05558436
What this trial is testing

Comparison of Diagnostic Sensitivity Between ctDNA Methylation and CEA in Colorectal Cancer

Who this might be right for
Colorectal Tumor
Nanfang Hospital, Southern Medical University 662
Early research (Phase 1)Ended earlyNCT00003434
What this trial is testing

Biological Therapy in Stage I, Stage II, or Stage III Surgically Resected Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Duke University 8
Early research (Phase 1)Active Not RecruitingNCT05464030
What this trial is testing

Anti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01)

Who this might be right for
Colorectal Cancer
EMD Serono Research & Development Institute, Inc. 220
Early research (Phase 1)WithdrawnNCT01273402
What this trial is testing

Study of TF2 Carcinoembryonic Antigen (CEA) Antibody in Patients With Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Gilead Sciences
Testing effectiveness (Phase 2)Looking for participantsNCT07387081
What this trial is testing

Phase II Study of LM-24C5

Who this might be right for
Advanced Solid Tumor Cancer
LaNova Medicines Limited 130
Testing effectiveness (Phase 2)Ended earlyNCT00012246
What this trial is testing

Vaccine Therapy in Treating Patients With Cancer of the Gastrointestinal Tract

Who this might be right for
Colorectal CancerEsophageal CancerExtrahepatic Bile Duct Cancer+4 more
The University of Texas Medical Branch, Galveston 7
Testing effectiveness (Phase 2)Ended earlyNCT04659603
What this trial is testing

Tusamitamab Ravtansine Monotherapy and in Combination in Patients With CEACAM5-positive Advanced Solid Tumors

Who this might be right for
Breast Cancer MetastaticPancreatic Carcinoma Metastatic
Sanofi 50
Testing effectiveness (Phase 2)Ended earlyNCT04524689
What this trial is testing

Tusamitamab Ravtansine (SAR408701) in Combination With Pembrolizumab and Tusamitamab Ravtansine (SAR408701) in Combination With Pembrolizumab and Platinum-based Chemotherapy With or Without Pemetrexed in Patients With NSQ NSCLC

Who this might be right for
Non-squamous Non-small-cell Lung Cancer (NSQ NSCLC)
Sanofi 57
Large-scale testing (Phase 3)Looking for participantsNCT07549412
What this trial is testing

Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)

Who this might be right for
Metastatic Colorectal Cancer
EMD Serono Research & Development Institute, Inc. 1,020
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