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Results for “CLDN18.2 Positive”

58 trials

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Showing 20 of 58 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07151872
What this trial is testing

Combination of QLS31905 and Chemotherapy ± QL2107 in Patients With CLDN18.2-positive Advanced Biliary Tract Cancer

Who this might be right for
CLDN18.2-positive Advanced Biliary Tract Cancer
Qilu Pharmaceutical Co., Ltd. 120
Large-scale testing (Phase 3)Looking for participantsNCT06901531
What this trial is testing

Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

Who this might be right for
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or CancerLocally Advanced Unresectable Gastric Adenocarcinoma or CancerMetastatic Gastric Adenocarcinoma or Cancer+1 more
Astellas Pharma Global Development, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT07483567
What this trial is testing

IBI343 in Combination With Sintilimab and SOX Regimen for Perioperative Treatment of Resectable, Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
CLDN18.2 PositivePrimary Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Innovent Biologics (Suzhou) Co. Ltd. 90
Testing effectiveness (Phase 2)Looking for participantsNCT06038396
What this trial is testing

RC118 Plus Toripalimab / RC148 in Patients with Locally Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Advanced Solid Tumor
RemeGen Co., Ltd. 48
Testing effectiveness (Phase 2)Looking for participantsNCT07483554
What this trial is testing

IBI343 in Combination Therapy for Advanced Malignant Solid Tumors

Who this might be right for
CLDN18.2 PositiveGastric/Gastroesophageal Junction AdenocarcinomaPancreatic Ductal Adenocarcinoma
Innovent Biologics (Suzhou) Co. Ltd. 389
Testing effectiveness (Phase 2)Ended earlyNCT05008445
What this trial is testing

Study of LM-102 in Patients With Advance Solid Tumors

Who this might be right for
Advanced Solid Tumor
LaNova Medicines Development Co., Ltd. 11
Testing effectiveness (Phase 2)Looking for participantsNCT06962137
What this trial is testing

Phase II RAINSPOT: Zolbetuximab-Paclitaxel-Ramucirumab for CLDN18.2 Positive Gastro-esophageal Cancer

Who this might be right for
Gastric Cancer Adenocarcinoma MetastaticGastric Adenocarcinoma and Gastroesophageal Junction Adenocarcinoma
Universitaire Ziekenhuizen KU Leuven 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT03816163
What this trial is testing

Zolbetuximab (IMAB362) in Adults With Pancreatic Cancer

Who this might be right for
Pancreatic CancerMetastatic Pancreatic CancerMetastatic Pancreatic Adenocarcinoma
Astellas Pharma Global Development, Inc. 393
Large-scale testing (Phase 3)Looking for participantsNCT07284134
What this trial is testing

JS107 vs Investigator's Choice as Second-line or Later Therapy for Advanced CLDN18.2-Positive Gastricor GEJ Adenocarcinoma.

Who this might be right for
Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
Shanghai Junshi Bioscience Co., Ltd. 560
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06942767
What this trial is testing

Combination of QLS31905, QL2107 and Chemotherapy as First-line Therapy in CLDN18.2-positive Unresectable Locally Advanced or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Qilu Pharmaceutical Co., Ltd. 100
Large-scale testing (Phase 3)Looking for participantsNCT07431281
What this trial is testing

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

Who this might be right for
Gastric CancerGastroesophageal Junction AdenocarcinomaEsophageal Cancer
AstraZeneca 2,130
Early research (Phase 1)Ended earlyNCT04735796
What this trial is testing

Study of LM-102 in Subjects in Advanced Tumors

Who this might be right for
Advanced Solid Tumors
LaNova Medicines Limited 9
Not applicableUnknownNCT04989010
What this trial is testing

Safety Study of 89Zr-Anti-CLDN18.2 mAbs PET Imaging in Patients With CLDN18.2 Positive Solid Tumors

Who this might be right for
Solid Tumor, Adult
Wuxi No. 4 People's Hospital 20
Early research (Phase 1)Study completedNCT05199519
What this trial is testing

Study to Evaluate the Safety, Tolerance, Pharmacokinetics and Preliminary Efficacy of IBI345

Who this might be right for
CLDN18.2 Positive Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd. 7
Testing effectiveness (Phase 2)Looking for participantsNCT05934331
What this trial is testing

A LM-302 Combination With Other Anti-Tumor Therapies Phase ll Study

Who this might be right for
Malignant Neoplasms of Digestive Organs
LaNova Medicines Zhejiang Co., Ltd. 276
Testing effectiveness (Phase 2)Looking for participantsNCT06519591
What this trial is testing

Systemic Application of Cadonilimab, LM-302, and S-1 Combined With Intraperitoneal Infusion of Paclitaxel for the Treatment of Claudin 18.2-positive Gastric Cancer With Peritoneal Metastasis

Who this might be right for
Gastric Cancer Stage IVPeritoneal Metastases
Ruijin Hospital 40
Early research (Phase 1)Active Not RecruitingNCT06396091
What this trial is testing

Zolbetuximab With Chemotherapy in Adults With Pancreatic Cancer

Who this might be right for
Metastatic Pancreatic Adenocarcinoma
Astellas Pharma Global Development, Inc. 12
Large-scale testing (Phase 3)Looking for participantsNCT07385703
What this trial is testing

Clinical Study on the Efficacy and Safety of LM-302 Injection Combined With Tislelizumab and Tislelizumab Combined Chemotherapy for the Treatment of Gastric or Gastroesophageal Junction Adenocarcinoma.

Who this might be right for
Adenocarcinoma
Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. 752
Testing effectiveness (Phase 2)Looking for participantsNCT07444541
What this trial is testing

ANO31905 in Combination With Chemotherapy for CLDN18.2-Positive Locally Advanced Unresectable or Metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Anova Innovation Limited 84
Early research (Phase 1)Study completedNCT01671774
What this trial is testing

Safety and Activity of IMAB362 in Combination With Zoledronic Acid and Interleukin-2 in CLDN18.2-positive Gastric Cancer

Who this might be right for
CLDN18.2-positive Gastric AdenocarcinomaCLDN18.2-positive Adenocarcinoma of the Gastroesophageal JunctionCLDN18.2-positive Adenocarcinoma of Esophagus
Astellas Pharma Global Development, Inc. 29
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