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Results for “CLDN18.2 Positive”

54 trials

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Showing 20 of 54 results

Large-scale testing (Phase 3)Looking for participantsNCT07103668
What this trial is testing

A Phase III Randomized Study in CLDN18.2-positive Unresectable Locally Advanced Gastric Cancer Patients

Who this might be right for
Gastric Adenocarcinoma
Suzhou Immunofoco Biotechnology Co., Ltd 150
Testing effectiveness (Phase 2)Study completedNCT01630083
What this trial is testing

Efficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer

Who this might be right for
CLDN18.2-positive Adenocarcinoma of the Gastroesophageal JunctionCLDN18.2-positive Adenocarcinoma of EsophagusCLDN18.2-positive Gastric Adenocarcinoma
Astellas Pharma Global Development, Inc. 252
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07444541
What this trial is testing

ANO31905 in Combination With Chemotherapy for CLDN18.2-Positive Locally Advanced Unresectable or Metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Anova Innovation Limited 84
Very early researchLooking for participantsNCT07595237
What this trial is testing

A IIT Study of 177Lu-DOTA-SNA040

Who this might be right for
Advanced Solid Tumors (Such as Gastric Cancer)Advanced Solid Tumors (Such as Adenocarcinoma at the Gastroesophageal Junction)Advanced Solid Tumors (Such as Pancreatic Cancer)+1 more
SmartNuclide Biopharma 12
Early research (Phase 1)Looking for participantsNCT05857332
What this trial is testing

SG1906 for CLDN18.2-Positive Solid Tumors

Who this might be right for
Locally Advanced Unresectable or Metastatic Solid Tumors
Hangzhou Sumgen Biotech Co., Ltd. 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06942767
What this trial is testing

Combination of QLS31905, QL2107 and Chemotherapy as First-line Therapy in CLDN18.2-positive Unresectable Locally Advanced or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

Who this might be right for
Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Qilu Pharmaceutical Co., Ltd. 100
Large-scale testing (Phase 3)Looking for participantsNCT07284134
What this trial is testing

JS107 vs Investigator's Choice as Second-line or Later Therapy for Advanced CLDN18.2-Positive Gastricor GEJ Adenocarcinoma.

Who this might be right for
Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
Shanghai Junshi Bioscience Co., Ltd. 560
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07151872
What this trial is testing

Combination of QLS31905 and Chemotherapy ± QL2107 in Patients With CLDN18.2-positive Advanced Biliary Tract Cancer

Who this might be right for
CLDN18.2-positive Advanced Biliary Tract Cancer
Qilu Pharmaceutical Co., Ltd. 120
Testing effectiveness (Phase 2)Looking for participantsNCT05205850
What this trial is testing

RC118 in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

Who this might be right for
Advanced Solid Tumor
RemeGen Co., Ltd. 135
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07108504
What this trial is testing

Efficacy and Safety of LM-302 Combined With Gemcitabine CLDN 18.2 Positive Unresectable Locally Advanced or Metastatic Pancreatic Cancer

Who this might be right for
Pancreatic CancerChemotherapy Effect
Shanghai Zhongshan Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT07483567
What this trial is testing

IBI343 in Combination With Sintilimab and SOX Regimen for Perioperative Treatment of Resectable, Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

Who this might be right for
CLDN18.2 PositivePrimary Gastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma
Innovent Biologics (Suzhou) Co. Ltd. 90
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07460375
What this trial is testing

Evaluate Claudin 18.2-Directed ADC LCB02A in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
LigaChem Biosciences, Inc. 191
Testing effectiveness (Phase 2)Active Not RecruitingNCT05994001
What this trial is testing

Candonilimab in Combination With LM-302 for Claudin 18.2 Positive-advanced Biliary Tract Cancer After Failure of Standard of Chemotherapy and PD1/PD-L1 Antibody

Who this might be right for
Biliary Tract CancerCandonilimabClaudin 18.2
Shanghai Zhongshan Hospital 78
Large-scale testing (Phase 3)Looking for participantsNCT06901531
What this trial is testing

Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

Who this might be right for
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or CancerLocally Advanced Unresectable Gastric Adenocarcinoma or CancerMetastatic Gastric Adenocarcinoma or Cancer+1 more
Astellas Pharma Global Development, Inc.
Early research (Phase 1)Looking for participantsNCT06084286
What this trial is testing

Dual-targeting CLDN18.2 and PD-L1 CAR-T for Patients with CLDN18.2-positive Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Sichuan University 29
Testing effectiveness (Phase 2)Looking for participantsNCT07556640
What this trial is testing

LM-302 and S-1 Plus Intraperitoneal Paclitaxel With or Without Cadonilimab for Claudin 18.2-positive Gastric or Gastroesophageal Junction Adenocarcinoma With Peritoneal Metastasis: a Prospective, Exploratory Study

Who this might be right for
Gastric Cancer Stage IVPeritoneal Metastases From Gastric CancerGastric or Esophagogastric Junction Adenocarcinoma
Ruijin Hospital 74
Early research (Phase 1)Ended earlyNCT04260191
What this trial is testing

Study of AMG 910 in Subjects With CLDN18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric and Gastroesophageal Junction Adenocarcinoma
Amgen 15
Large-scale testing (Phase 3)Active Not RecruitingNCT06351020
What this trial is testing

LM-302 for the Treatment of Subjects With Claudin18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma.

Who this might be right for
Locally Advanced or Metastatic GC and GCJ Adenocarcinoma
LaNova Medicines Zhejiang Co., Ltd. 387
Large-scale testing (Phase 3)Looking for participantsNCT07431281
What this trial is testing

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

Who this might be right for
Gastric CancerGastroesophageal Junction AdenocarcinomaEsophageal Cancer
AstraZeneca 2,130
Early research (Phase 1)Ended earlyNCT04735796
What this trial is testing

Study of LM-102 in Subjects in Advanced Tumors

Who this might be right for
Advanced Solid Tumors
LaNova Medicines Limited 9
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