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Results for “CML, Chronic Phase; TKI”

45 trials

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Showing 20 of 45 results

Not applicableEnded earlyNCT01073436
What this trial is testing

Discontinuation of Imatinib Mesylate in Patients With Chronic-Phase Chronic Myeloid Leukemia Previously Treated With Interferon-Alpha

Who this might be right for
Chronic Myeloid Leukemia
University of Michigan Rogel Cancer Center 7
Large-scale testing (Phase 3)Study completedNCT04666259
What this trial is testing

Asciminib in Monotherapy for Chronic Myeloid Leukemia in Chronic Phase (CML-CP) With and Without T315I Mutation

Who this might be right for
Chronic Myelogenous Leukemia - Chronic Phase
Novartis Pharmaceuticals 56
Large-scale testing (Phase 3)Ended earlyNCT02108951
What this trial is testing

Study to Assess Efficacy and Safety of Nilotinib 300mg Twice Daily in Patients With Philadelphia Positive Chronic Myeloid Leukaemia (CML) in Chronic Phase Who Are Intolerant to Prior Tyrosine Kinase Inhibitors.

Who this might be right for
Philidelphia Positive Chronic Myeloid Leukaemia
Novartis Pharmaceuticals 20
Large-scale testing (Phase 3)Study completedNCT01657604
What this trial is testing

TKI and Interferon Alpha Evaluation Initiated by the German Chronic Myeloid Leukemia Study Group - the TIGER Study

Who this might be right for
Chronic Myeloid Leukemia
University of Jena 717
Large-scale testing (Phase 3)Study completedNCT02204644
What this trial is testing

The Study of the Efficacy and the Safety of Flumatinib vs Imatinib as First Line Treatment in Patients With CML

Who this might be right for
CML, CML-CP,MMR,TKI
Jiangsu Hansoh Pharmaceutical Co., Ltd. 400
Early research (Phase 1)Study completedNCT01460498
What this trial is testing

Azacitidine (AZA) in Minimal Residual Disease (MRD) Chronic Myeloid Leukemia (CML)

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT03610971
What this trial is testing

Treatment Free Remission After Combination Therapy With Ruxolitinib Plus Tyrosine Kinase Inhibitors

Who this might be right for
Chronic Phase Chronic Myeloid LeukemiaChronic Myeloid Leukemia, Chronic Phase
H. Lee Moffitt Cancer Center and Research Institute 24
Testing effectiveness (Phase 2)UnknownNCT04835584
What this trial is testing

KRT-232 and TKI Study in Chronic Myeloid Leukemia

Who this might be right for
Chronic Myeloid Leukemia
Kartos Therapeutics, Inc. 109
Testing effectiveness (Phase 2)UnknownNCT03883087
What this trial is testing

A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Chronic Phase With T315I Mutation

Who this might be right for
Chronic Myeloid Leukemia, Chronic Phase
Ascentage Pharma Group Inc. 41
Testing effectiveness (Phase 2)Active Not RecruitingNCT04160546
What this trial is testing

Study to Evaluate the Reinduction and Second Stop of TKI with Ponatinib in CML in Molecular Response (ResToP)

Who this might be right for
Chronic Myeloid Leukemia, Chronic Phase
Fundacion CRIS de Investigación para Vencer el Cáncer 80
Testing effectiveness (Phase 2)Active Not RecruitingNCT03817398
What this trial is testing

Stopping Tyrosine Kinase Inhibitors in Affecting Treatment-Free Remission in Patients With Chronic Phase Chronic Myeloid Leukemia

Who this might be right for
Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive
Children's Oncology Group 110
Testing effectiveness (Phase 2)WithdrawnNCT02923986
What this trial is testing

Clinical Trial of BP1001 (Liposomal Grb2 Antisense Oligonucleotide) in Combination With Dasatinib in Patients With Ph + CML Who Have Failed TKI, Ph+ AML, Ph+ MDS

Who this might be right for
Chronic Myelogenous Leukemia, Ph1-PositiveAcute Myeloid LeukemiaMyelodysplastic Syndrome
Bio-Path Holdings, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT07354074
What this trial is testing

Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP

Who this might be right for
Chronic Myelogenous LeukemiaLeukemia, Myelogenous, Chronic, Philadelphia Chromosome Positive
Novartis Pharmaceuticals 50
Large-scale testing (Phase 3)Study completedNCT01596114
What this trial is testing

European Stop Tyrosine Kinase Inhibitor Study

Who this might be right for
Chronic Myeloid Leukemia
European LeukemiaNet 868
Not applicableUnknownNCT04739826
What this trial is testing

Flumatinib Versus Nilotinib for Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia

Who this might be right for
CML, Chronic Phase; TKI
The First Affiliated Hospital of Soochow University 491
Not applicableStudy completedNCT01188278
What this trial is testing

Treatment With Second Generation Tyrosine Kinase Inhibitors (2G TKI) Post Imatinib Failure Survey

Who this might be right for
Leukemia, Myeloid, Chronic-Phase (CML-CP)
Bristol-Myers Squibb 173
Large-scale testing (Phase 3)Active Not RecruitingNCT05456191
What this trial is testing

Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (≥18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP)

Who this might be right for
Philadelphia Chromosome-Positive Chronic Myeloid Leukemia
Novartis Pharmaceuticals 568
Large-scale testing (Phase 3)Not Yet RecruitingNCT07489755
What this trial is testing

TGRX-678 Chinese Phase III in Chronic Myelogenous Leukemia (CML) Patients

Who this might be right for
Chronic Myelogenous LeukemiaChronic Myelogenous Leukemia - Chronic Phase
Shenzhen TargetRx Co., Ltd. 180
Testing effectiveness (Phase 2)Ended earlyNCT01392170
What this trial is testing

Pegasys in Patients With Chronic Myeloid Leukemia (CML)

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 2
Testing effectiveness (Phase 2)Ended earlyNCT02906696
What this trial is testing

Bosutinib in Treating Patients With Chronic Myeloid Leukemia in Chronic Phase After Frontline TKI Failure

Who this might be right for
Blasts Under 15 Percent of Bone Marrow Nucleated CellsBlasts Under 15 Percent of Peripheral Blood White CellsBlasts Under 30 Percent of Bone Marrow Nucleated Cells+2 more
M.D. Anderson Cancer Center 8
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