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Results for “CYP2C19 Poor”

13 trials

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Showing 13 of 13 results

Early research (Phase 1)Study completedNCT00651638
What this trial is testing

ARQ 197 in Healthy Volunteers to Assess the Pharmacokinetic (PK) Profile in Extensive and Poor Metabolizers as Defined by Cytochrome P450 2C19 (CYP 2C19) Genotype

Who this might be right for
Healthy
ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) 17
Post-approval studies (Phase 4)Study completedNCT03092193
What this trial is testing

Pharmacogenetic and Pharmacokinetics of Naproxen and Associated Naproxen-esomeprazole

Who this might be right for
Poor Metabolizer Due to Cytochrome P450 CYP2C9 VariantPoor Metabolizer Due to Cytochrome p450 CYP2C19 Variant
University of Sao Paulo 8
Early research (Phase 1)Study completedNCT01251796
What this trial is testing

ARQ 197 in Combination With Erlotinib

Who this might be right for
Advanced/Recurrent Non-small-cell Lung Cancer
Kyowa Kirin Co., Ltd. 9
Testing effectiveness (Phase 2)Looking for participantsNCT06322238
What this trial is testing

Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice:

Who this might be right for
Pharmacogenomic Drug InteractionSide Effect of DrugIneffective Drug Action+2 more
Mayo Clinic 66
Early research (Phase 1)Study completedNCT02906176
What this trial is testing

Influence of SLCO2B1 Polymorphism on the PK of Voriconazole in CYP2C19 PM

Who this might be right for
Healthy Volunteers
Seoul National University Hospital 12
Not applicableStudy completedNCT02428660
What this trial is testing

Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM

Who this might be right for
Cytochrome P450 CYP2D6 Enzyme DeficiencyPoor Metabolizer Due to Cytochrome P450 CYP2D6 VariantUltrarapid Metabolizer Due to Cytochrome P450 CYP2D6 Variant+6 more
Genelex Corporation 341
Early research (Phase 1)Study completedNCT00766025
What this trial is testing

Study in Taiwanese Subjects Identified as CYP2C19 Poor and Extensive Metabolizers Receiving Rosuvastatin

Who this might be right for
CYP2C19 PoorExtensive Metabolizers
AstraZeneca 50
Large-scale testing (Phase 3)UnknownNCT02048228
What this trial is testing

Genotyping Guided Individualized Treatment of Clopidogrel and Ticagrelor in ACS

Who this might be right for
CLOPIDOGREL, POOR METABOLISM of (Disorder)
Chinese PLA General Hospital 200
Early research (Phase 1)Study completedNCT00931073
What this trial is testing

A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers

Who this might be right for
Alzheimer's DiseaseHuntington's Disease
Pfizer 24
Early research (Phase 1)Study completedNCT02248259
What this trial is testing

Drug Drug Interaction Trial With Strong CYP3A4 Inhibitor (Itraconazole) in CYP2C19 Extensive Metabolizers and Poor Metabolizers

Who this might be right for
Healthy
Boehringer Ingelheim 25
Not applicableStudy completedNCT02191358
What this trial is testing

YouScript IMPACT Registry

Who this might be right for
Adverse Drug EventsAdverse Drug ReactionsDrug Interaction Potentiation+10 more
Genelex Corporation 800
Not applicableUnknownNCT00162877
What this trial is testing

The Role of CYP2C19 on the Eradication of H. Pylori Infection:Implication of PK/PD Relationships

Who this might be right for
Peptic Ulcer With H. Pylori InfectionGastritis With H. Pylori Infection
National Taiwan University Hospital 80
Not applicableStudy completedNCT02378220
What this trial is testing

Pharmacogenetic Testing Among Home Health Patients

Who this might be right for
Adverse Drug EventsAdverse Drug ReactionsDrug Interaction Potentiation+10 more
Genelex Corporation 110