Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Cancer Predisposition Syndromes”

56 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 56 results

Not applicableUnknownNCT03015376
What this trial is testing

Inherited Susceptible Genes Among Epithelial Ovarian Cancer

Who this might be right for
Ovarian Neoplasm EpithelialHereditary Breast and Ovarian Cancer Syndrome
Peking Union Medical College Hospital 1,000
Not applicableLooking for participantsNCT01247597
What this trial is testing

DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study

Who this might be right for
Pleuropulmonary BlastomaCystic NephromaOvarian Sertoli-Leydig Cell Tumors+2 more
National Cancer Institute (NCI) 1,500
Not applicableActive Not RecruitingNCT03246841
What this trial is testing

Investigation of Tumour Spectrum of Germline Mutations in Breast and Ovarian Cancer Genes.

Who this might be right for
Hereditary Breast and Ovarian CancerMutation
UNICANCER 7,274
Not applicableUnknownNCT06163365
What this trial is testing

Inherited Cancer Early Diagnosis (ICED) Study

Who this might be right for
Li Fraumeni SyndromeLynch SyndromeHereditary Diffuse Gastric Cancer+5 more
Royal Marsden NHS Foundation Trust 100
Not applicableStudy completedNCT02289326
What this trial is testing

Biomarker Monitoring in TP53 Mutation Carriers

Who this might be right for
Li-Fraumeni SyndromeHereditary Cancer SyndromesTP53 Gene Germline Mutation Carrier
Scripps Health 6
Not applicableLooking for participantsNCT07378423
What this trial is testing

Questionnaire on Congenital Cancer Signs Through Self-Assessment

Who this might be right for
Cancer Predisposition SyndromesPediatric CancerChildhood Neoplasms+1 more
Insel Gruppe AG, University Hospital Bern 205
Not applicableLooking for participantsNCT05463796
What this trial is testing

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

Who this might be right for
Cancer RiskCancer Predisposition SyndromeHereditary Cancer Prediction+28 more
Dana-Farber Cancer Institute 5,000
Not applicableLooking for participantsNCT04903782
What this trial is testing

Cancer Predisposition Testing by Family-based Whole-genome Sequencing (WGS) in Every Child With Newly Diagnosed Cancer

Who this might be right for
Neoplastic Syndromes, HereditaryCancerGenetic Predisposition to Disease
Sydney Children's Hospitals Network 270
Not applicableLooking for participantsNCT05129605
What this trial is testing

Prostate Cancer Genetic Risk Evaluation and Screening Study

Who this might be right for
Prostatic NeoplasmProstate CancerBRCA2 Mutation+5 more
Massachusetts General Hospital 400
Not applicableStudy completedNCT05736497
What this trial is testing

Care Plans for Cancer Predisposition

Who this might be right for
Genetic Predisposition
Children's Hospital of Philadelphia 177
Not applicableLooking for participantsNCT01441089
What this trial is testing

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

Who this might be right for
Prostate CancerBreast CancerLung Cancer+2 more
National Cancer Institute (NCI) 1,100
Not applicableLooking for participantsNCT06022016
What this trial is testing

Study of Families With an Hemopathies Predisposition Related to the DDX41 Gene.

Who this might be right for
DDX41 Gene Mutation
Institut Claudius Regaud 910
Not applicableLooking for participantsNCT02705846
What this trial is testing

Analysing Outcomes After Prostate Cancer Diagnosis and Treatment in Carriers of Rare Germline Mutations

Who this might be right for
Prostate Cancer
Institute of Cancer Research, United Kingdom 4,260
Early research (Phase 1)Looking for participantsNCT06090669
What this trial is testing

Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency

Who this might be right for
Inherited Bone Marrow Failure SyndromeFamilial Platelet Disorder With Predisposition to Myeloid Malignancies
National Cancer Institute (NCI) 75
Not applicableUnknownNCT04145388
What this trial is testing

Family History Study on Cancer Risk

Who this might be right for
Lynch SyndromeColorectal CancerBreast Cancer+3 more
Kaiser Permanente 18,623
Not applicableLooking for participantsNCT06888388
What this trial is testing

Long-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast Cancer

Who this might be right for
Breast Cancer Surgery
Sir Mortimer B. Davis - Jewish General Hospital 4,700
Not applicableActive Not RecruitingNCT05759143
What this trial is testing

Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing

Who this might be right for
Genetic Predisposition to DiseaseGenetic Predisposition
Dana-Farber Cancer Institute 40
Not applicableLooking for participantsNCT04731857
What this trial is testing

Diagnostic Value of Exome/ Genome Sequencing, Conventional Methods in Rare Diseases and Familial Tumor Syndromes

Who this might be right for
Rare DiseasesGenetic Predisposition
University Hospital Tuebingen 12,000
Not applicableStudy completedNCT05721326
What this trial is testing

Sequential EHR Based Interventions to Increase Genetic Testing for Breast and Ovarian Cancer Predisposition

Who this might be right for
Genetic Predisposition to DiseaseBreast Cancer FemaleOvarian Cancer+4 more
Abramson Cancer Center at Penn Medicine 1,283
Testing effectiveness (Phase 2)Looking for participantsNCT05960773
What this trial is testing

Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma

Who this might be right for
MesotheliomaMalignant Mesothelioma (MM)Early-stage Mesothelioma+3 more
National Cancer Institute (NCI) 15
Next Page