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Results for “Cancers With DNA Repair-Deficiency”

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Showing 20 of 0 results

Early research (Phase 1)Looking for participantsNCT05687110
What this trial is testing

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

Who this might be right for
Metastatic Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
National Cancer Institute (NCI) 43
Early research (Phase 1)Ended earlyNCT04458259
What this trial is testing

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

Who this might be right for
Neoplasm Metastasis
Pfizer 88
Not applicableUnknownNCT03357978
What this trial is testing

Susceptibility to Infections, Tumor Risk and Liver Disease in Patients With Ataxia Telangiectasia

Who this might be right for
Ataxia Telangiectasia
Johann Wolfgang Goethe University Hospital 30
Testing effectiveness (Phase 2)Ended earlyNCT03600909
What this trial is testing

The Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi Anemia

Who this might be right for
Fanconi AnemiaMyelodysplastic Syndrome (MDS)Acute Myelogenous Leukemia (AML)
Memorial Sloan Kettering Cancer Center 3
Large-scale testing (Phase 3)UnknownNCT04711434
What this trial is testing

PD-1 Antibody for The Prevention of Adenomatous Polyps and Second Primary Tumors in Lynch Syndrome Patients

Who this might be right for
Lynch Syndrome
Sun Yat-sen University 260
Testing effectiveness (Phase 2)UnknownNCT03831698
What this trial is testing

Omega 3 Fatty Acids in Colorectal Cancer (CRC) Prevention in Patients With Lynch Syndrome (COLYNE)

Who this might be right for
Colorectal CancerLynch Syndrome
University of Kansas Medical Center 21
Not applicableStudy completedNCT05252819
What this trial is testing

Whole Body MRI for Cancer Surveillance in A-T

Who this might be right for
Ataxia Telangiectasia
University of Nottingham 32
Not applicableStudy completedNCT02570516
What this trial is testing

NBI Versus Indigo Carmine During Colonoscopy in Lynch Syndrome

Who this might be right for
Lynch Syndrome
Assistance Publique - Hôpitaux de Paris 141
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07408583
What this trial is testing

Prenatal Transplantation for Fetuses With Fanconi Anemia

Who this might be right for
Fanconi AnemiaAnemia, Hypoplastic, CongenitalCongenital Bone Marrow Failure Syndromes+5 more
Agnieszka Czechowicz 12
Large-scale testing (Phase 3)Ended earlyNCT00566644
What this trial is testing

Intrauterine Levonorgestrel and Observation or Observation Alone in Preventing Atypical Endometrial Hyperplasia and Endometrial Cancer in Women With Hereditary Non-Polyposis Colorectal Cancer or Lynch Syndrome

Who this might be right for
Endometrial CancerHereditary Non-polyposis Colon Cancer (hmsh2, hmlh1, hpms1, hpms2)
St George's, University of London 600
Early research (Phase 1)Study completedNCT04095273
What this trial is testing

Study to Test How Well Patients With Advanced Solid Tumors Respond to Treatment With the Elimusertib in Combination With Pembrolizumab, to Find the Optimal Dose for Patients, How the Drug is Tolerated and the Way the Body Absorbs, Distributes and Discharges the Drug

Who this might be right for
Advanced Solid Tumors
Bayer 56
Testing effectiveness (Phase 2)Active Not RecruitingNCT06710847
What this trial is testing

Investigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

Who this might be right for
Neoplasms, ColorectalSolid TumorColon Cancer+2 more
GlaxoSmithKline 14
Not applicableEnrolling By InvitationNCT07381985
What this trial is testing

Strategy for Management of Patients With Hereditary Cancer Syndromes (HCS) in a Rural Environment

Who this might be right for
Hereditary Cancer SyndromesBRCA1 Hereditary Breast and Ovarian Cancer SyndromeLynch Syndrome
University of Vermont Medical Center 200
Testing effectiveness (Phase 2)Ended earlyNCT03631641
What this trial is testing

Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial Colectomy

Who this might be right for
Colon AdenomaColon CarcinomaLynch Syndrome+2 more
John Hays 3
Early research (Phase 1)Study completedNCT02635672
What this trial is testing

Phase I Dose Escalation Study for VIP152 in Patients With Advanced Cancer

Who this might be right for
Neoplasms
Vincerx Pharma, Inc. 110
Large-scale testing (Phase 3)Study completedNCT01464086
What this trial is testing

LIFSCREEN : Evaluation of Whole Body MRI for Early Detection of Cancers in Subjects With P53 Mutation (Li-Fraumeni Syndrome)

Who this might be right for
Li Fraumeni Syndrome
Gustave Roussy, Cancer Campus, Grand Paris 107
Testing effectiveness (Phase 2)Ended earlyNCT04258111
What this trial is testing

IBI310 in Combination with Sintilimab in Patients with DNA Mismatch Repair Deficient (dMMR)/microsatellite Instability High (MSI-H) Locally-advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Innovent Biologics (Suzhou) Co. Ltd. 4
Not applicableNot Yet RecruitingNCT07445828
What this trial is testing

Evaluation of Capsule Colonoscopy in Patients With Lynch Syndrome

Who this might be right for
Lynch Syndrome
Region Skane 78
Not applicableStudy completedNCT03047226
What this trial is testing

Diagnosis of Lynch Syndrome Based on Next-generation Sequencing in Colorectal Cancer

Who this might be right for
Lynch Syndrome
Second Affiliated Hospital, Zhejiang University, School of Medicine 311
Testing effectiveness (Phase 2)Looking for participantsNCT06047379
What this trial is testing

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Who this might be right for
Diffuse Astrocytoma, IDH-MutantGlioblastoma, IDH-wildtypeBrain Metastases, Adult+18 more
Neonc Technologies, Inc. 134
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