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Results for “Ceftolozane/Tazobactam”

32 trials

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Showing 20 of 32 results

Not applicableUnknownNCT03941951
What this trial is testing

Study to Optimize the Use of New Antibiotics

Who this might be right for
Bacterial InfectionsFungal Infection
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 900
Not applicableUnknownNCT04196608
What this trial is testing

In Vitro Activity of Ceftolozane/Tazobactam and Imipenem/Relebactam in Clinical Isolates of Pseudomonas Aeruginosa and Enterobacterales Collected From Hematology and Oncology Patients

Who this might be right for
Ceftolozane/TazobactamImipenem/RelebactamHematology and Oncology
Emilio Bouza 1,005
Post-approval studies (Phase 4)Ended earlyNCT04673175
What this trial is testing

Ceftolozane-Tazobactam for Directed Treatment of Pseudomonas Aeruginosa Bacteremia and Pneumonia in Patients With Hematological Malignancies and Hematopoietic Stem Cell Transplantation

Who this might be right for
PneumoniaHematologic MalignancyPseudomonas Aeruginosa Infection+2 more
Weill Medical College of Cornell University 17
Not applicableUnknownNCT04257812
What this trial is testing

Monitoring of Ceftolozane-Tazobactam Plasmatic Levels in Critical Patients

Who this might be right for
Serious Infection
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 20
Post-approval studies (Phase 4)Study completedNCT02421120
What this trial is testing

Population Pharmacokinetics and Safety of Intravenous Ceftolozane/Tazobactam in Adult Cystic Fibrosis Patients

Who this might be right for
Cystic FibrosisCystic Fibrosis Pulmonary ExacerbationPseudomonas Aeruginosa Infection
Joseph L. Kuti, PharmD 21
Not applicableStudy completedNCT05048693
What this trial is testing

Use of New Antibiotics in Sweden

Who this might be right for
Multi-antibiotic Resistance
Uppsala University 41
Large-scale testing (Phase 3)Study completedNCT03830333
What this trial is testing

Ceftolozane/Tazobactam (MK-7625A) Plus Metronidazole Versus Meropenem for Participants With Complicated Intra-abdominal Infection (MK-7625A-015)

Who this might be right for
Complicated Intra-abdominal Infections
Merck Sharp & Dohme LLC 268
Large-scale testing (Phase 3)Ended earlyNCT01853982
What this trial is testing

Study of Intravenous Ceftolozane/Tazobactam Compared to Piperacillin/Tazobactam in Ventilator-Associated Pneumonia

Who this might be right for
Ventilator-Associated Pneumonia (VAP)
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 4
Not applicableStudy completedNCT02962934
What this trial is testing

An Observational Pharmacokinetic Sudy of Ceftolozane-Tazobactam in Intensive Care Unit in Patients With and Without CRRT

Who this might be right for
Gram-Negative Bacterial Infections
Royal Brisbane and Women's Hospital 18
Early research (Phase 1)Study completedNCT02508753
What this trial is testing

Safety Study Designed to Study the Effects of Two Different Doses of CXA-101/Tazobactam, a Low Dose and a High Dose, on the QT/QTc Intervals in Healthy Subjects

Who this might be right for
Healthy
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 52
Large-scale testing (Phase 3)Study completedNCT02070757
What this trial is testing

Safety and Efficacy Study of Ceftolozane/Tazobactam to Treat Ventilated Nosocomial Pneumonia (MK-7625A-008)

Who this might be right for
Healthcare-Associated PneumoniaVentilator-Associated PneumoniaLung Diseases
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 726
Early research (Phase 1)Study completedNCT02266706
What this trial is testing

Pharmacokinetic and Safety Study of Ceftolozane/Tazobactam in Pediatric Participants Receiving Antibiotic Therapy for Proven or Suspected Gram-negative Infection or for Peri-operative Prophylaxis (MK-7625A-010)

Who this might be right for
Proven or Suspected Gram-negative Bacterial InfectionPeri-operative Prophylaxis
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 43
Testing effectiveness (Phase 2)Study completedNCT03217136
What this trial is testing

MK-7625A Plus Metronidazole Versus Meropenem in Pediatric Participants With Complicated Intra-Abdominal Infection (cIAI) (MK-7625A-035)

Who this might be right for
Complicated Intra-Abdominal Infection
Merck Sharp & Dohme LLC 94
Testing effectiveness (Phase 2)Study completedNCT03485950
What this trial is testing

Comparative Study To Determine The Efficacy, Safety, And Tolerability Of Ceftolozane-Tazobactam

Who this might be right for
Other Infectious Diseases
M.D. Anderson Cancer Center 100
Testing effectiveness (Phase 2)Study completedNCT03230838
What this trial is testing

MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034)

Who this might be right for
Complicated Urinary Tract InfectionPyelonephritis
Merck Sharp & Dohme LLC 134
Post-approval studies (Phase 4)Looking for participantsNCT06342115
What this trial is testing

Ceftolozane/Tazobactam Versus Meropenem for Febrile Neutropenia on Patients Colonized With or at Risk for Infection With Extended Spectrum Beta Lactamase - Producing Pathogens

Who this might be right for
Febrile Neutropenia
Beneficência Portuguesa de São Paulo 55
Not applicableStudy completedNCT04679610
What this trial is testing

In Vitro Activity of Ceftolozane-tazobactam Against Contemporary Nosocomial Gram "-" Pathogens Isolated in Russia

Who this might be right for
Nosocomial Infection
The Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy (IACMAC) 700
Post-approval studies (Phase 4)WithdrawnNCT05061654
What this trial is testing

CEFtolozane-Tazobactam for the Empiric Anti-bacterial Treatment of Neutropenic Fever in Hematology Patients

Who this might be right for
Neutropenia, FebrileHematologic Cancer
Hamad Medical Corporation
Not applicableUnknownNCT04352855
What this trial is testing

Ceftolozane-tazobactam for the Treatment of Respiratory Infections Due to Extensively Drug-resistant Pseudomonas Aeruginosa Among Critically Ill Patients: a Retrospective Study.

Who this might be right for
Ventilator Associated PneumoniaAntibiotic Resistant Infection
Semmelweis University 55
Early research (Phase 1)Study completedNCT02387372
What this trial is testing

Plasma Pharmacokinetics (PK) & Lung Penetration of Ceftolozane/Tazobactam in Participants With Pneumonia (MK-7625A-007)

Who this might be right for
Critically IllPneumonia
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 37
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