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Results for “Child-Pugh Score”

111 trials

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Showing 20 of 111 results

Early research (Phase 1)Study completedNCT05814926
What this trial is testing

GP681 in Volunteers With Hepatic Impairment Compared With Healthy Volunteers

Who this might be right for
Healthy VolunteersHepatic Impairment
Jiangxi Qingfeng Pharmaceutical Co. Ltd. 24
Early research (Phase 1)Study completedNCT01392807
What this trial is testing

Open-label Study to Assess the Pharmacokinetics of NKTR-118 in Patients With Impaired Hepatic Function

Who this might be right for
Hepatic; Functional Disturbance
AstraZeneca 24
Testing effectiveness (Phase 2)Study completedNCT00073736
What this trial is testing

Safety and Tolerability of I.V. Infusion of MB07133 in Patients With Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Ligand Pharmaceuticals 28
Early research (Phase 1)Ended earlyNCT04136444
What this trial is testing

A Pharmacokinetic Study of Padsevonil in Study Participants With Either Normal or Moderately Impaired Hepatic Function

Who this might be right for
Healthy Study ParticipantsImpaired Hepatic Function
UCB Biopharma S.P.R.L. 12
Large-scale testing (Phase 3)Temporarily pausedNCT02271295
What this trial is testing

Impact on Morbidity and Mortality of Prophylactic Dosing of Low Molecular Heparin in Child-Pugh B Cirrhotic Patients

Who this might be right for
Cirrhosis
Assistance Publique - Hôpitaux de Paris 16
Not applicableEnded earlyNCT00375011
What this trial is testing

Breath Test to Assess Hepatic Metabolic Reserve and to Predict Hepatic Decompensation in Cirrhotics

Who this might be right for
Cirrhosis
Meridian Bioscience, Inc. 200
Testing effectiveness (Phase 2)UnknownNCT05009680
What this trial is testing

A Single and Repeat Dose Trial in Participants With Hepatic Impairment

Who this might be right for
Hepatic Impairment
Galecto Biotech AB 54
Testing effectiveness (Phase 2)Study completedNCT01232296
What this trial is testing

Dovitinib Versus Sorafenib in Adult Patients With Hepatocellular Carcinoma (HCC) as a First Line Treatment

Who this might be right for
Hepatocellular Carcinoma
Novartis Pharmaceuticals 162
Early research (Phase 1)Study completedNCT01839604
What this trial is testing

A Phase I/Ib Study of AZD9150 (ISIS-STAT3Rx) in Patients With Advanced/Metastatic Hepatocellular Carcinoma

Who this might be right for
Advanced Adult Hepatocellular CarcinomaHepatocellular Carcinoma Metastatic
AstraZeneca 58
Testing effectiveness (Phase 2)Looking for participantsNCT06823713
What this trial is testing

RTX001 Autologous Engineered Macrophages for Liver Cirrhosis

Who this might be right for
End-stage Liver Disease (ESLD)Cirrhosis, LiverCirrhosis, Decompensated+5 more
Resolution Therapeutics Limited 30
Testing effectiveness (Phase 2)Study completedNCT01830127
What this trial is testing

BI 207127 / Faldaprevir Combination Therapy in Hepatic Impairment (Child-Pugh B) Patients With Genotype 1b Chronic Hepatitis C Infection: HCVerso3

Who this might be right for
Hepatitis C, Chronic
Boehringer Ingelheim 35
Testing effectiveness (Phase 2)Looking for participantsNCT06526104
What this trial is testing

Study of Tremelimumab and Durvalumab (MEDI4736) (T300+D) in Advanced Hepatocellular Carcinomas With Child-Pugh-B Cirrhosis

Who this might be right for
Hepatocellular CarcinomaCirrhosis, Liver
The University of Texas Health Science Center at San Antonio 32
Early research (Phase 1)Ended earlyNCT04252417
What this trial is testing

HI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Hepatic Impaired Patients and Healthy Subjects

Who this might be right for
Healthy VolunteersHepatic Impairment of Moderate Child Pugh Category
MedDay Pharmaceuticals SA 15
Large-scale testing (Phase 3)Ended earlyNCT01405573
What this trial is testing

Sorafenib in First-line Treatment of Advanced B Child Hepatocellular Carcinoma

Who this might be right for
Advanced Adult Hepatocellular Carcinoma
National Cancer Institute, Naples 35
Early research (Phase 1)Study completedNCT04454424
What this trial is testing

Study on the Safety of BAY1817080, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug in Participants With Impaired Liver Function or Normal Liver Function

Who this might be right for
Endometriosis Related PainOveractive BladderDiabetic Neuropathic Pain+1 more
Bayer 37
Early research (Phase 1)Looking for participantsNCT05490888
What this trial is testing

Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver Cirrhotics

Who this might be right for
Cirrhosis, LiverLiver FibrosisAscites Hepatic
PharmaIN 74
Post-approval studies (Phase 4)Study completedNCT01846455
What this trial is testing

Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired Subjects

Who this might be right for
Hepatic FailureHepatic ImpairmentChronic Hepatitis C Infection With Hepatic Coma
Indivior Inc. 43
Testing effectiveness (Phase 2)Ended earlyNCT01097083
What this trial is testing

Coriolus Versicolor as Palliative Therapy Compared to Placebo in Patients With Child-Pugh C Unresectable Hepatocellular Carcinoma

Who this might be right for
CarcinomaTherapy
National University Hospital, Singapore 20
Large-scale testing (Phase 3)Active Not RecruitingNCT05883644
What this trial is testing

Durvalumab and Tremelimumab as First Line Treatment in Participants With Advanced Hepatocellular Carcinoma (HCC)

Who this might be right for
Advanced Hepatocellular Carcinoma
AstraZeneca 111
Early research (Phase 1)Not Yet RecruitingNCT06994572
What this trial is testing

Study of CT-01 as Monotherapy and Combination Therapy in Subjects With Intermediate or Advanced Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma (HCC)
Captor Therapeutics S.A. 141
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