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Results for “Chromosomal Rearrangement”

115 trials

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Showing 20 of 115 results

Not applicableNot Yet RecruitingNCT06694129
What this trial is testing

Real-world Observational Study of Targeted Therapy in Patients With Advanced ROS1-positive NSCLC

Who this might be right for
Non-Small Cell Lung CancerROS1 Gene RearrangementResistance+1 more
National Cancer Center, China 40
Not applicableLooking for participantsNCT06023472
What this trial is testing

Microfluidic Chip vs Density Gradient Centrifugation on the Euploidy Rate of Pre-implantation Genetic Testing

Who this might be right for
InfertilityGenetic DiseaseChromosomal Rearrangement+1 more
Professor Ernest Hung-Yu Ng 318
Testing effectiveness (Phase 2)Active Not RecruitingNCT03944772
What this trial is testing

Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)

Who this might be right for
Non-Small Cell Lung Cancer
AstraZeneca 247
Early research (Phase 1)Looking for participantsNCT05544019
What this trial is testing

Study of SGR-1505 in Mature B-Cell Neoplasms

Who this might be right for
Mature B-Cell NeoplasmNon Hodgkin LymphomaDLBCL+23 more
Schrödinger, Inc. 98
Not applicableUnknownNCT06424379
What this trial is testing

BCL6-rearrangements Implications in Non-Hodgkin Lymphomas.

Who this might be right for
Non Hodgkin LymphomaFollicular LymphomaMarginal Zone Lymphoma+1 more
Hospices Civils de Lyon 135
Testing effectiveness (Phase 2)WithdrawnNCT01854372
What this trial is testing

Rituximab-HyperCVAD (R-HCVAD) Alternating With Rituximab-Methotrexate-Cytarabine- (R-MC) in Newly Diagnosed Patients With Diffuse Large B-Cell Lymphoma With MYC-Rearrangement.

Who this might be right for
Newly Diagnosed Diffuse Large B-Cell LymphomaIntermediate (Burkitt-Like) Lymphoma
The University of Texas Health Science Center at San Antonio
Testing effectiveness (Phase 2)Ended earlyNCT04003610
What this trial is testing

Pemigatinib + Pembrolizumab vs Pemigatinib Alone vs Standard of Care for Urothelial Carcinoma (FIGHT-205)

Who this might be right for
Metastatic Urothelial CarcinomaUnresectable Urothelial Carcinoma
Incyte Corporation 7
Early research (Phase 1)Not Yet RecruitingNCT07355335
What this trial is testing

Ziftomenib + Mezigdomide in Adolesc. and Adults w/ R/R AML

Who this might be right for
KMT2A-rearrangedNPM1-mutant Refractory or Relapsed AML
Massachusetts General Hospital 24
Not applicableLooking for participantsNCT05122806
What this trial is testing

Analysis of Biological Characteristics of Advanced ALK-rearranged NSCLC

Who this might be right for
Non-small Cell Lung CancerALK Gene Rearrangement Positive
Groupe Francais De Pneumo-Cancerologie 100
Testing effectiveness (Phase 2)Looking for participantsNCT04988555
What this trial is testing

Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

Who this might be right for
Leukemia, Myeloid, AcuteLeukemia, Lymphocytic, AcuteMultiple Myeloma+1 more
Sumitomo Pharma America, Inc. 606
Early research (Phase 1)Active Not RecruitingNCT02321501
What this trial is testing

Ceritinib and Everolimus in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIB-IV Non-small Cell Lung Cancer

Who this might be right for
ALK PositiveLocally Advanced Malignant Solid NeoplasmMetastatic Malignant Solid Neoplasm+3 more
M.D. Anderson Cancer Center 37
Not applicableStudy completedNCT02372448
What this trial is testing

Multicenter Validation of the Sensitivity of Theranostic ALK Rearrangement Detection by FISH Analysis and Prevalence of Escaping Mutations in Circulating Tumor Cells for the Non-invasive Management of Lung Cancer Patients

Who this might be right for
Lung Neoplasms
Centre Hospitalier Universitaire de Nice 206
Not applicableStudy completedNCT02451761
What this trial is testing

Apparently Balanced Chromosomal Translocation/ Next-generation Sequencing/ Intellectual Disability

Who this might be right for
Intellectual DisabilityCongenital Abnormalities
Hospices Civils de Lyon 55
Testing effectiveness (Phase 2)Active Not RecruitingNCT05202782
What this trial is testing

Zanubrutinib and CAR T-cell Therapy for the Treatment of Recurrent or Refractory Aggressive B-cell Non-Hodgkin's Lymphoma or Transformed Indolent B-cell Lymphoma

Who this might be right for
Diffuse Large B-Cell Lymphoma Associated With Chronic InflammationEBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedHigh Grade B-Cell Lymphoma, Not Otherwise Specified+16 more
Northwestern University
Not applicableStudy completedNCT05109962
What this trial is testing

Management of Robertsonian Translocation PGT-SR Attempts

Who this might be right for
Robertsonian Translocation
University Hospital, Montpellier 148
Testing effectiveness (Phase 2)Study completedNCT01823068
What this trial is testing

Vandetanib in Advanced NSCLC With RET Rearrangement

Who this might be right for
Non Small Cell Lung Cancer
Samsung Medical Center 17
Not applicableLooking for participantsNCT05724004
What this trial is testing

Alectinib Followed by Concomitant Consolidation Radiation Therapy in Advanced NSCLC With ALK-rearrangement (A-SAB)

Who this might be right for
Radiotherapy Side EffectNon-small Cell Lung CancerALK Gene Mutation
Karolinska University Hospital 70
Testing effectiveness (Phase 2)WithdrawnNCT05718297
What this trial is testing

Brigatinib Post Definitive Chemo-radiotherapy in Patients with ALK-fusion Non-small Cell Lung Cancer

Who this might be right for
NSCLC, Stage IIIALK-rearrangement
ETOP IBCSG Partners Foundation
Testing effectiveness (Phase 2)Looking for participantsNCT06249191
What this trial is testing

Mosunetuzumab With Chemotherapy for the Treatment of Patients With Untreated C-Myc Rearrangement Positive High Grade B Cell Lymphoma or Diffuse Large B Cell Lymphoma

Who this might be right for
Diffuse Large B-Cell LymphomaHigh Grade B-Cell Lymphoma
OHSU Knight Cancer Institute 40
Testing effectiveness (Phase 2)Looking for participantsNCT06834373
What this trial is testing

Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy

Who this might be right for
Large B-Cell Lymphoma With IRF4 RearrangementRecurrent Aggressive B-Cell Non-Hodgkin LymphomaRecurrent ALK-Positive Large B-Cell Lymphoma+28 more
Mayo Clinic 41
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