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Results for “Chromosome Translocation”

50 trials

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Showing 20 of 50 results

Post-approval studies (Phase 4)Study completedNCT01061177
What this trial is testing

Nilotinib in Newly Diagnosed Adult Philadelphia Chromosome & /or BCR-ABL Positive Chronic Myeloid Leukaemia in Chronic Phase

Who this might be right for
CML in Chronic Phase
Novartis Pharmaceuticals 1,090
Large-scale testing (Phase 3)Study completedNCT01254188
What this trial is testing

Safety and Efficacy of Nilotinib in Newly Diagnosed Chronic Myeloid Leukemia Patients

Who this might be right for
Chronic Myeloid Leukemia
Novartis Pharmaceuticals 421
Not applicableStudy completedNCT01118507
What this trial is testing

Trisomy of Chromosome 21 Diagnosis by High Output Sequencing

Who this might be right for
Trisomy 21 - Translocation
Assistance Publique - Hôpitaux de Paris 976
Testing effectiveness (Phase 2)Study completedNCT00261846
What this trial is testing

Study Evaluating SKI-606 (Bosutinib) In Philadelphia Chromosome Positive Leukemias

Who this might be right for
Chronic Myeloid Leukemia
Pfizer 571
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07636564
What this trial is testing

Testing Blinatumomab With or Without Revumenib in Patients With B-cell Acute Lymphoblastic Leukemia With a Genetic Change Requiring More Treatment

Who this might be right for
Acute Leukemia of Ambiguous LineageB Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative+1 more
SWOG Cancer Research Network 90
Testing effectiveness (Phase 2)UnknownNCT03249870
What this trial is testing

Study of Inotuzumab Ozogamicin Combined to Chemotherapy in Older Patients With Philadelphia Chromosome-negative CD22+ B-cell Precursor ALL

Who this might be right for
Acute Lymphoblastic Leukemia (ALL) - Philadelphia Chromosome (Ph)-Negative CD22+ B-cell Precursor (BCP)
Versailles Hospital 130
Not applicableStudy completedNCT03509896
What this trial is testing

Study of Chinese Newly Diagnosed Participants With Philadelphia Chromosome-Positive (Ph+) Chronic Myeloid Leukemia in Chronic Phase (CML-CP)

Who this might be right for
Chronic Myeloid LeukemiaPhiladelphia ChromosomeChronic Myeloid Leukemia in Chronic Phase
Bristol-Myers Squibb 463
Not applicableStudy completedNCT05216068
What this trial is testing

Investigation and Diagnosis of the Chromosome Variation in Donated/abandoned Blastocyst

Who this might be right for
Chromosome TranslocationGenetic Disorders in PregnancyRecurrent Miscarriage
Chang Gung Memorial Hospital 57
Early research (Phase 1)Study completedNCT00428909
What this trial is testing

Effect of Imatinib Mesylate and the Pharmacokinetics of Acetaminophen/Paracetamol in Patients With Newly Diagnosed, Previously Untreated Chronic Myeloid Leukemia in Chronic Phase (CML-CP)

Who this might be right for
Chronic Myeloid Leukemia (CML)
Novartis Pharmaceuticals 12
Testing effectiveness (Phase 2)Looking for participantsNCT06220487
What this trial is testing

A Single-arm, Open-label Study of Olverembatinib, CD3/CD19 Bispecific T-cell Engager, and Chidamide in Patients With Newly Diagnosed Ph+ALL

Who this might be right for
Acute Lymphoblastic LeukemiaPhiladelphia ChromosomePhiladelphia-Positive ALL+2 more
Nanfang Hospital, Southern Medical University 67
Large-scale testing (Phase 3)Study completedNCT01511289
What this trial is testing

Radotinib Versus Imatinib in Newly Diagnosed Philadelphia Chromosome and Chronic Myeloid Leukemia Chronic Phase Patients

Who this might be right for
LeukemiaLeukemia, MyeloidLeukemia, Myelogenous, Chronic, BCR-ABL Positive+3 more
Il-Yang Pharm. Co., Ltd. 242
Early research (Phase 1)Study completedNCT03448393
What this trial is testing

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

Who this might be right for
Lymphoma, Non-HodgkinLeukemia, Lymphocytic, B CellB-Cell Lymphoma+7 more
National Cancer Institute (NCI) 54
Testing effectiveness (Phase 2)WithdrawnNCT04845035
What this trial is testing

Pediatric-Inspired Chemotherapy Plus Tyrosine Kinase Inhibitor in Adult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia
University of Michigan Rogel Cancer Center
Testing effectiveness (Phase 2)Study completedNCT01058434
What this trial is testing

Safety and Efficacy of TKI258 in Relapsed or Refractory Multiple Myeloma Patients, Who Are With or Without t(4;14) Chromosomal Translocation

Who this might be right for
Relapsed or Refractory Multiple Myeloma
Novartis Pharmaceuticals 43
Testing effectiveness (Phase 2)Study completedNCT05433532
What this trial is testing

Study of Azacitidine，Venetoclax，and Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP Patients

Who this might be right for
Philadelphia ChromosomeAcute Myeloid LeukemiaAcute Lymphoblastic Leukemia+2 more
The First Affiliated Hospital of Soochow University 20
Testing effectiveness (Phase 2)Study completedNCT01602952
What this trial is testing

Philadelphia Chromosome Positive CML Patients Without Optimal Response or Tolerance to Bcr-Abl TKI

Who this might be right for
LeukemiaLeukemia, MyeloidLeukemia, Myelogenous, Chronic, BCR-ABL Positive+2 more
Il-Yang Pharm. Co., Ltd. 85
Testing effectiveness (Phase 2)Study completedNCT00171249
What this trial is testing

An Extension Study to Determine the Safety and Anti-Leukemic Effects of Imatinib Mesylate in Adult Participants With Ph+ Leukemia

Who this might be right for
Philadelphia Positive Chronic Myeloid LeukemiaAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia
Novartis Pharmaceuticals 293
Very early researchStudy completedNCT01826708
What this trial is testing

Breakpoint Analysis of de Novo Apparently Balanced Chromosomal Translocations

Who this might be right for
Balanced Chromosomal Translocation
University Hospital, Montpellier 10
Testing effectiveness (Phase 2)Study completedNCT01745640
What this trial is testing

Pomalidomide and Dexamethasone Effects in Multiple Myeloma Patients With Del 17p or t (4;14)

Who this might be right for
Multiple Myeloma
University Hospital, Lille 63
Not applicableStudy completedNCT02451761
What this trial is testing

Apparently Balanced Chromosomal Translocation/ Next-generation Sequencing/ Intellectual Disability

Who this might be right for
Intellectual DisabilityCongenital Abnormalities
Hospices Civils de Lyon 55
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