Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)”

53 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 53 results

Not applicableStudy completedNCT03484780
What this trial is testing

VisONE Heart Failure Study: Pilot

Who this might be right for
Heart Failure With Reduced Ejection Fraction, HFrEF
VisCardia Inc. 15
Not applicableStudy completedNCT06486844
What this trial is testing

An Observational Study Called ROVER to Learn More About How Well Vericiguat Works in People Who Were Newly Treated With Vericiguat in Routine Medical Care in Germany

Who this might be right for
Chronic Heart Failure With Reduced Ejection Fraction
Bayer 500
Not applicableStudy completedNCT02570087
What this trial is testing

Benefits of CTO-PCI in Selected Cases With HFrEF (CTOHFrEF)

Who this might be right for
Chronic Total Occlusion Vessel
Hospital Clinic of Barcelona 39
Testing effectiveness (Phase 2)Active Not RecruitingNCT06369298
What this trial is testing

Study of JK07 in Patients With Chronic Heart Failure

Who this might be right for
Heart Failure With Reduced Ejection FractionHeart Failure With Preserved Ejection Fraction
Salubris Biotherapeutics Inc 282
Testing effectiveness (Phase 2)Study completedNCT06215911
What this trial is testing

Assess Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Reduced Ejection Fraction (Cycle-1-REF)

Who this might be right for
Heart FailureHeart Failure With Reduced Ejection FractionCardiovascular Diseases+1 more
Cardurion Pharmaceuticals, Inc. 557
Not applicableStudy completedNCT06363110
What this trial is testing

An Observational Study to Learn More About Vericiguat Treatment Patterns and Its Safety in People With Chronic Heart Failure With Reduced Ejection Fraction in Routine Medical Care in the United States

Who this might be right for
Chronic Heart Failure With Reduced Ejection Fraction
Bayer 1,400
Testing effectiveness (Phase 2)Study completedNCT06195930
What this trial is testing

Learn How Safe Starting Vericiguat at a Dose of 5 Milligrams is in Participants With Chronic Heart Failure With Reduced Ejection Fraction

Who this might be right for
Chronic Heart Failure With Reduced Ejection Fraction
Bayer 106
Post-approval studies (Phase 4)Looking for participantsNCT07405944
What this trial is testing

Vericiguat and Reverse Remodeling Indices in Heart Failure

Who this might be right for
Heart Failure With Reduced Ejection Fraction (HFrEF)Chronic Heart Failure
University Medical Centre Ljubljana 60
Post-approval studies (Phase 4)Ended earlyNCT05737186
What this trial is testing

SGLT2 Inhibitors and Treatment of Heart Failure in Severe Renal Insufficiency

Who this might be right for
Heart Failure With Reduced Ejection FractionRenal Insufficiency, Chronic
Peking University People's Hospital 11
Not applicableNot Yet RecruitingNCT07614295
What this trial is testing

Effects of Repletion of Sodium Chloride on Natriuresis, Blood Pressure, and Neurohormonal Activity in Patients With Chronic Heart Failure With Reduced Ejection Fraction

Who this might be right for
Chronic Heart Failure With Reduced Ejection Fraction
Wroclaw Medical University 30
Not applicableStudy completedNCT07527767
What this trial is testing

Secondary Use of PARALLEL-HF Data

Who this might be right for
Chronic Heart Failure and Reduced Ejection Fraction (HFrEF)
Novartis Pharmaceuticals 236
Large-scale testing (Phase 3)Study completedNCT05093933
What this trial is testing

Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-035)

Who this might be right for
Chronic Heart Failure With Reduced Ejection Fraction
Merck Sharp & Dohme LLC 6,106
Large-scale testing (Phase 3)Study completedNCT03448419
What this trial is testing

This Study Tests Empagliflozin in Patients With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF). The Study Looks at How Far Patients Can Walk in 6 Minutes and at Their Heart Failure Symptoms

Who this might be right for
Heart Failure
Boehringer Ingelheim 312
Not applicableActive Not RecruitingNCT06632483
What this trial is testing

An Observational Study to Learn More About How Safe Vericiguat is and How Well it Works in Indian People With Chronic Heart Failure With Reduced Ejection Fraction and Worsening Chronic Heart Failure Under Real World Conditions

Who this might be right for
Chronic Heart Failure With Reduced Ejection FractionWorsening Chronic Heart Failure
Bayer 604
Not applicableNot Yet RecruitingNCT07355088
What this trial is testing

Precision Subtyping and Prognostic Study of Heart Failure Based on Multi-Omics Integration and Clinical Indicators: A Prospective Single-Center Cohort Study

Who this might be right for
Chronic Heart FailureHeart Failure With Reduced Ejection Fraction (HFrEF)Heart Failure With Preserved Ejection Fraction (HFPEF)+1 more
Xinjiang Medical University 600
Post-approval studies (Phase 4)Not Yet RecruitingNCT07697833
What this trial is testing

Comparing the Efficacy and Safety of Vericiguat With Standard Medical Treatment in Heart Failure Patients

Who this might be right for
Heart Failure With Reduced Ejection Fraction (HFrEF)
National Institute of Cardiovascular Diseases, Pakistan 500
Testing effectiveness (Phase 2)Looking for participantsNCT07029503
What this trial is testing

Swedish Cardiac And Renal Failure Study-1

Who this might be right for
HFrEF - Heart Failure With Reduced Ejection FractionChronic Kidney Disease
Karolinska Institutet 40
Large-scale testing (Phase 3)Study completedNCT03036124
What this trial is testing

Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure

Who this might be right for
Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)
AstraZeneca 4,744
Post-approval studies (Phase 4)Looking for participantsNCT07259512
What this trial is testing

Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease Patients With Reduced Ejection Fraction Heart Failure

Who this might be right for
Chronic Kidney DiseaseHeart Failure With Reduced Ejection Fraction (HFrEF)
Evi Liliek Wulandari 80
Not applicableStudy completedNCT04793880
What this trial is testing

Cost and Shared Decision-Making for Heart Failure

Who this might be right for
Chronic Heart Failure
Emory University 247
Next Page